Ampelopsis Cantoniensis Extract | 30% Dihydromyricetin (DHM) + Myricetin by HPLC
Clinically Validated Liver Protector & Metabolic Regulator
HPLC-Quantified Synergy for Alcohol Metabolism, Detoxification & Mitochondrial Support
Dual-Active Power: Science-Backed Mechanisms
1. Dihydromyricetin (DHM):
- Alcohol Metabolism: Accelerates ethanol breakdown via ADH/ALDH* enzyme activation
- Hepatoprotection: Reduces oxidative stress in liver cells (Nrf2 pathway activation)
- Mitochondrial Optimization: Enhances cellular energy (AMPK/PGC-1α modulation)
2. Myricetin:
- Advanced Glycation End (AGE) Inhibitor: Protects against metabolic aging
- Neuroguard: Crosses BBB to combat neuroinflammation (TNF-α/IL-6 reduction)*
- Sirtuin Activation: Promotes longevity pathways
Synergy Effect: 30% combined potency ensures 3.2x greater bioavailability vs. isolated DHM (J. Ethnopharmacol, 2023)
Why HPLC Quantification Matters
| Parameter | Generic Extract | Our HPLC Standardized Extract |
|---|---|---|
| Active Concentration | 5-15% (Unverified) | Guaranteed 30% DHM+Myricetin |
| Batch Consistency | ±40% Variability | <5% Deviation (ISO 17025) |
| Heavy Metal Control | Often Unmonitored | <1 ppm Lead/Cadmium |
| Clinical Relevance | Insufficient Dosing | Human-Effective Dosage (300mg/day) |
Technical Specifications
| Parameter | Specification |
|---|---|
| Source | Ampelopsis cantoniensis (Leaves), Wildcrafted S. China |
| Active Ratio | 20% Dihydromyricetin + 10% Myricetin (HPLC) |
| Appearance | Pale Yellow Fine Powder |
| Solubility | Water & Ethanol Soluble (Nanoemulsion Tech Available) |
| Identification | HPLC-DAD/UV, Confirmed by Reference Standards |
| Residual Solvents | Meets ICH Q3C Guidelines |
| Microbiology | Total Plate Count < 500 CFU/g |
| Aflatoxins | < 2 ppb (HPLC-FLD) |
Certifications & Compliance
- cGMP (21 CFR 111/117)
- ISO 22000 Certified Facility
- Vegan & Non-GMO
- Heavy Metal Compliance: EU 1881/2006, Prop 65
- GRAS Self-Affirmed Dossier
- FDA Dietary Ingredient Master File (In Progress)
Target Applications
- Liver Health Supplements: Alcohol detox formulas, hangover prevention*
- Metabolic Wellness: Blood sugar/triglyceride management complexes
- Anti-Aging Nutraceuticals: AGE inhibitor & mitochondrial support
- Sports Nutrition: Post-exercise recovery blends
- Functional Beverages: Alcohol-counteracting drink additives
*Combine with NAC & Milk Thistle for amplified detox effects
Differentiation Drivers
✅ Wildcrafted Sourcing: Optimal flavonoid profile vs. cultivated varieties
✅ Dual-Phase Extraction: Subcritical H2O → Ethanol-Free Purification
✅ 3rd-Party Bioactivity Testing: In vitro hepatocyte protection data included
✅ Stability: 36-month shelf life (accelerated testing at 40°C/75% RH)
Keywords
*Ampelopsis Cantoniensis Extract, Dihydromyricetin HPLC, DHM 30%, Myricetin Extract, Alcohol Metabolism Supplement, Hangover Prevention Ingredient, Liver Detox Botanicals, Natural AMPK Activator, Mitochondrial Support Supplement, DHM + Myricetin Synergy, Anti-AGE Natural Compound, Hepatoprotective Extract, Ethanol Breakdown Support, cGMP Botanical Extract, Clinical-Grade Dihydromyricetin, Metabolic Regulator Ingredient, NAD+ Booster Natural, Heavy Metal-Free DHM*
