Apigenin Powder 98%

Short Description:

Apigenin Powder 98% is a highly concentrated, plant-based flavonoid extracted from sources like chamomile, parsley, and celery. Known for its powerful antioxidant and anti-inflammatory properties, Apigenin has gained significant attention in the health and wellness community. With a purity of 98%, our Apigenin Powder offers a premium, bioavailable form of this beneficial compound, making it an ideal choice for those seeking natural solutions to support overall health.Apigenin (CAS 520-36-5), a natural flavonoid with the molecular formula C₁₅H₁₀O₅, is a potent bioactive compound derived from plants such as chamomile, parsley, and celery . This 98% pure powder, verified by HPLC analysis , is a crystalline solid with a pale yellow appearance, offering exceptional stability when stored at -20°C . Its broad-spectrum biological activities make it a cornerstone in advanced biomedical and nutraceutical research.

FOB Price: US 5 - 2000 / KG

Min.Order Quantity: 1 KG

Supply Ability: 10000 KG/per Month

Port: Shanghai /Beijing

Payment Terms: L/C,D/A,D/P,T/T,O/A

Shipping Terms: By sea/By Air/By Courier

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Product Detail

Product Tags

Product Name: Apigenin Powder
Purity: ≥98%
CAS Number: 520-36-5
Molecular Formula: C₁₅H₁₀O₅
Molecular Weight: 270.24 g/mol
Appearance: Light yellow to yellow fine powder
Source: Naturally extracted from plants such as chamomile, celery, parsley, and citrus fruits
Solubility: Soluble in DMSO (54 mg/mL), insoluble in water and ethanol
Density: 1.55 g/cm³
Loss on Drying: ≤1%
Storage Conditions: Store at room temperature, protected from light and moisture. For long-term storage, keep at -20°C.
Shelf Life: 24 months from the date of production

Key Features and Biological Activities

Apigenin is a naturally occurring flavonoid compound with a wide range of biological activities, including:

Antioxidant Properties: Apigenin effectively scavenges free radicals, reducing oxidative stress and protecting cells from damage .
Anti-inflammatory Effects: It inhibits the production and release of inflammatory mediators, making it useful in the treatment of inflammatory diseases .
Anticancer Activity: Apigenin has demonstrated significant anti-carcinogenic properties, inhibiting the proliferation of cancer cells and inducing apoptosis. It is particularly effective against melanoma, colon cancer, and breast cancer .
MAP Kinase Inhibitor: It acts as a competitive inhibitor of CYP2C9 and has been shown to inhibit the MAP kinase pathway, which is involved in cell proliferation and survival .
Anxiolytic and Sedative Effects: As a ligand for central benzodiazepine receptors, apigenin exhibits anxiolytic and mild sedative effects .
Non-toxic and Non-mutagenic: Compared to other flavonoids like quercetin and kaempferol, apigenin is less toxic and non-mutagenic, making it a safer option for research and therapeutic applications .

Applications

Apigenin is widely used in various fields due to its diverse biological activities:

Pharmaceutical Research: Apigenin is a valuable tool in the development of chemopreventive and chemotherapeutic agents for cancer. It is used in studies on cancer cell proliferation, metastasis, and apoptosis .
Nutraceutical and Dietary Supplements: As a natural antioxidant, apigenin is added to food and beverage products to enhance their nutritional value and support immune function .
Cosmetics: Due to its antioxidant and anti-inflammatory properties, apigenin is used in skincare products to reduce skin inflammation, improve skin quality, and protect against UVB radiation .
Weight Management: Apigenin is also used in weight management products, where it may help regulate metabolism and reduce oxidative stress .

Safety and Handling

Precautions for Cell Culture: Use DMSO as a solvent with a final concentration <0.3% for cell culture applications. Avoid using non-sterile products without pre-treatment to remove pyrogens and bacteria .
Animal Studies: For animal studies, use DMSO with a final concentration <5% and consider adding solubilizers like Tween, CMC-NA, or glycerol .
Storage and Handling: Store the product in a cool, dry place, away from moisture and light. For long-term storage, keep at -20°C. Avoid inhalation, skin, and eye contact. In case of exposure, rinse immediately and seek medical advice .

Quality Assurance

Certifications: The product is certified with a Certificate of Analysis (COA), Good Manufacturing Practice (GMP), and ISO standards .
Testing Methods: The purity is confirmed by HPLC and UV-Vis spectrophotometry .
Third-Party Testing: The product is tested by internationally authorized third-party laboratories to ensure compliance with international quality standards .

Conclusion

Apigenin Powder 98% is a high-purity flavonoid compound with a wide range of biological activities, including antioxidant, anti-inflammatory, and anticancer properties. Its safety profile, combined with its diverse applications in pharmaceutical, nutraceutical, and cosmetic industries, makes it a valuable compound for research and development. Whether used in cancer prevention, skincare, or dietary supplements, apigenin offers a natural and effective solution for various health and wellness needs.