Product Name: Calcium Alpha-Ketoglutarate Monohydrate
CAS Number: 71686-01-6 or 402726-78-7
Chemical Formula: C₅H₄CaO₅·H₂O or C₅H₆CaO₆
Molecular Weight: 184.16 g/mol (CAS 71686-01-6) or 202.18 g/mol (CAS 402726-78-7)
Appearance: White powder
Purity: 98% or higher
Storage Conditions: Store in a cool, dry place, away from direct sunlight. For long-term storage, keep at -20°C for powder or -80°C for solutions.
Shelf Life: 2 years when stored properly .
Product Description
Calcium Alpha-Ketoglutarate Monohydrate is a calcium salt form of α-ketoglutarate, a key intermediate in the tricarboxylic acid (TCA) cycle, also known as the Krebs cycle. This compound plays a vital role in cellular energy production and metabolism. It is widely used in research and development for its potential benefits in enhancing cellular repair, detoxification, and metabolic function .
Calcium Alpha-Ketoglutarate Monohydrate is the calcium salt form of α-ketoglutarate, a key intermediate in the tricarboxylic acid (TCA) cycle, which is essential for energy production in cellular metabolism. It is widely used in research and development for its potential role in enhancing cellular energy metabolism, supporting detoxification, and promoting cellular health .
This compound is also known as Calcium 2-oxoglutarate Monohydrate or Alpha-Ketoglutarate Calcium Monohydrate. It is commonly used in scientific studies related to metabolic disorders, aging, and muscle health. Some studies suggest that Calcium Alpha-Ketoglutarate may help prevent muscle mass loss and support healthy aging by optimizing energy metabolism
Key Features:
- High Purity: Available in 98% or higher purity, suitable for research and pharmaceutical applications.
- Versatile Applications: Used in research for studying metabolic pathways, cellular energy production, and anti-aging effects.
- Safety: Non-toxic and safe for use in laboratory settings.
- Customization Options: Available in various packaging sizes (e.g., 1 kg, 25 kg) and can be customized for specific research needs .
Applications
Research Use:
- Metabolic Studies: Calcium Alpha-Ketoglutarate Monohydrate is used in studies related to energy metabolism, oxidative stress, and cellular health.
- Anti-Aging Research: It has been shown to support healthy aging by promoting cellular energy production and reducing oxidative damage .
- Muscle Health: Some studies suggest that it may help maintain muscle mass and support muscle growth by optimizing energy metabolism .
Industrial Use:
- Pharmaceutical Industry: Used as a precursor in the synthesis of various pharmaceutical compounds.
- Food and Supplement Industry: Used in the formulation of dietary supplements and functional foods .
Synthesis and Manufacturing
The manufacturing process involves the synthesis of α-ketoglutarate through oxidative deamination of glutamate, followed by reaction with a calcium source to form the calcium salt. The product is then purified using techniques such as crystallization, filtration, and drying to ensure high purity and quality .
Regulatory and Safety Information
- Regulatory Status: This product is intended for research use only and is not approved for human consumption or clinical use.
- Handling Precautions: Handle with care to avoid inhalation or skin contact. Store in a well-ventilated area.
- Environmental Impact: The product is non-toxic and environmentally friendly when disposed of properly .
Conclusion
Calcium Alpha-Ketoglutarate Monohydrate is a valuable compound for researchers and industries involved in metabolic studies, pharmaceutical development, and functional food formulation. Its high purity, safety, and versatility make it a preferred choice for a wide range of applications.
