Inositol

Inositol (hexahydroxycyclohexane) is a widely distributed natural constituent of plant and animal tissues. The animal tissues richest in inositol are brain, heart, stomach, kidney, spleen, and liver, where it occurs free or as a component of phospholipids. Among plants, cereals are rich sources of inositol, particularly in the form of polyphosphoric acid esters, called phytic acids. Although there are several possible optically active and inactive isomers, considerations of inositol as a food additive refer specifically to optically inactive cis-1,2,3,5-trans-4,6-cyclohexanehexol, which is preferably designated myo-inositol. Pure inositol is a stable, white, sweet, crystalline compound. The Food Chemicals Codex specifies that it assay not less than 97.0 percent, melt between 224 and 227°, and contain not more than 3 ppm arsenic, 10 ppm lead, 20 ppm heavy metals (as Pb), 60 ppm sulfate, and 50 ppm chloride. Inositol was thought for a time to be a vitamin because experimental animals on a synthetic diet developed clinical signs that were corrected by inositol supplementation. However, no cofactor or catalytic function for inositol has been found; it can be synthesized and occurs in relatively high concentration in animal tissues. These factors argue against its classification as a vitamin. A dietary requirement in man has not been established.

Varenavn: Inositol

Specifikation: Min 97,0%

Kemiske egenskaber: Hvid krystal eller krystallinsk pulver, lugtfri og søde; Relativ densitet: 1,752 (vandfrit), 1,524 (dihydrat), smp 225 ~ 227 ℃ (vandfri), 218 ° C (dihydrat), kogepunkt 319 ° C. Opløst i vand (25 ° C, 14 g / 100 ml; 60 ° C, 28 g / 100 ml), tungt opløseligt i ethanol, eddikesyre, ethylenglycol og glycerol, uopløseligt i ether, acetone og chloroform. Stabilt i luften; Varmestabil, syre og base, men er hygroskopisk.

CAS: 87-89-8

Content Analysis: Afvej nøjagtigt 200 mg prøve (fortørret ved 105 ° C i 4 timer), og placere den i en 250 ml bægerglas. Tilføje 5 ml af en blanding mellem en svovlsyre (TS-241) afprøvning opløsning og 50 eddikesyreanhydrid, og derefter dække urglasset. Efter opvarmning på et dampbad i 20 minutter, afkøles på et isbad, tilsæt 100 ml vand, og kog 20min. Efter afkøling overføres prøven i en 250 ml skilletragt, idet en lille mængde vand. Successivt bruge 30, 25, 20, 15, 10 og 5 ml chloroform for at ekstrahere opløsningen i seks gange (første skylle bægerglasset). Alle chloroformekstrakten blev opsamlet i en anden 250m1 skilletragt. Vask den blandede ekstrakt med 10 ml vand. Sætte chloroformopløsningen gennem en tragt vat og overføre den til en 150 ml forud vejet soxhletkolben. Bruge 10 ml chloroform til vaske skilletragt og tragten, og inkorporeres i ekstraktet. Fordampe det til tørhed på et dampbad, og derefter overføre det i en ovn ved 105 ° C til tørring af 1 time. Cool det i en ekssikkator og vejer det. Bruge den opnåede mængde af seks inositol acetat ganges med 0,4167, nemlig den tilsvarende mængde af inositol (C6H12O6).

Fungere:

1. As food supplements, has a similar effect to vitamin B1. It can be used for infant foods and used in an amount of 210~250mg/kg; Used in drinking in an amount of 25~30mg/kg.
2. Inositol is an indispensible vitamin for lipid metabolism in the body. It can promote the absorption of hypolipidemic medicines and vitamins. Moreover, it can promote the cell growth and fat metabolism in liver and other tissues. It can be used for the adjuvant treatment of fatty liver, high cholesterol. It is widely used in food and feed additives, and is often added to fish, shrimp and livestock feed. The amount is 350-500mg/kg.
3. The product is one kind of the complex vitamin B, which can promote cell metabolism, improve the cell nutrient conditions, and can contribute to development, increase appetite, to recuperate. Moreover, it can prevent the accumulation of fat in the liver, and accelerate the process of removing excess fat in heart. It has a similar lipid-chemotactic action as choline, and therefore useful in the treatment of hepatic fatty excessive disease and cirrhosis of the liver disease. According to the “food fortifier use of health standards (1993)” (Issued by the Ministry of Health of China), it can be used for infant food and fortified beverages at an amount of 380-790mg/kg. It is a vitamin class medicines and lipid-lowering drug which promote the fat metabolism of liver and other tissues, and be useful for the adjuvant treatment of fatty liver and high cholesterol. It is widely used in additives of food and beverage.
4. Inositol is widely used in pharmaceutical, chemical, food, etc. It has a good effect on treating diseases such as liver cirrhosis. It can also used for advanced cosmetic raw materials, with high economic value.
5. It can be used as a biochemical reagent and also for the pharmaceutical and organic synthesis; It can lower the level cholesterol and have sedative effect.