Product Name:Fisetin
- Active Ingredient: Fisetin ≥98% (HPLC)
- CAS No.: 528-48-3
- Molecular Formula: C₁₅H₁₀O₆
- Appearance: Bright yellow powder
- Solubility: Soluble in ethanol, DMSO; slightly soluble in water
- Plant Source: Cotinus coggygria leaves and stems
- Certifications: GMP, ISO 9001, COA (Certificate of Analysis) provided
Fisetin is a natural flavonoid compound derived from various fruits and vegetables, including strawberries, apples, and onions. It is a yellow or light yellow powder with a high purity level (≥98%) and is widely recognized for its potent antioxidant, anti-inflammatory, and neuroprotective properties. Fisetin is also known for its potential anticancer and anti-aging effects, making it a valuable ingredient in health supplements, functional foods, and cosmetics .
Chemical Properties
- Molecular Formula: C₁₅H₁₀O₆
- Molecular Weight: 286.24
- CAS Number: 528-48-3
- Appearance: Light yellow to yellow powder
- Solubility: Soluble in ethanol, acetone, and acetic acid; slightly soluble in water and DMSO
- Storage: Store at 2–8°C in sealed, light-protected conditions to maintain stability and purity .
Biological Activities
Fisetin exhibits a wide range of biological activities, including:
- Antioxidant: Fisetin scavenges free radicals and reduces oxidative stress, protecting cells from damage .
- Anti-inflammatory: It inhibits the production of pro-inflammatory cytokines such as TNF-α, IL-1β, and IL-6, reducing inflammation in various conditions .
- Neuroprotective: Fisetin supports brain health by protecting neurons from oxidative damage and promoting synaptic plasticity, which may enhance memory and cognitive function .
- Anticancer: Fisetin induces apoptosis in cancer cells, inhibits tumor growth, and disrupts signaling pathways such as PI3K/AKT/mTOR, which are involved in cancer progression .
- Anti-aging: Fisetin activates sirtuins, which are associated with longevity and cellular health, and may help delay aging-related diseases .
- Metabolic Regulation: It may assist in weight loss by blocking the activation of the mTOR protein, which is linked to fat accumulation .
Applications
Fisetin is applicable in various fields, including:
- Health Supplements: Enhances cognitive function, reduces inflammation, and supports overall well-being .
- Functional Foods: Incorporated into biscuits, beverages, and other food products to provide health benefits .
- Cosmetics: Used in skincare products for its anti-aging, whitening, and skin cell-activating properties .
- Pharmaceuticals: Research is ongoing to develop Fisetin-based formulations for the treatment of chronic diseases, including cancer, diabetes, and neurodegenerative disorders .
Quality and Safety
- Purity: Fisetin is typically tested using HPLC to ensure a purity of ≥98% .
- Certifications: Products are produced under GMP (Good Manufacturing Practices) and may be ISO or FDA certified, ensuring compliance with international standards .
- Toxicity: Animal studies have shown that Fisetin is generally safe, with no significant side effects observed in most cases .
- Allergies: Fisetin is considered allergen-free and is suitable for use in a wide range of products .
Packaging and Delivery
- Packaging: Available in 5g units, vacuum-sealed bags, and bulk containers (e.g., 25kg drums).
- Shipping: Delivered via express, air, or sea freight, with options for customized packaging and labeling .
- Lead Time: Orders are typically shipped within 3–10 days, depending on the quantity and production schedule .
Conclusion
Fisetin Powder is a high-quality, natural compound with a wide range of health benefits, supported by extensive scientific research. Its unique combination of antioxidant, anti-inflammatory, and neuroprotective properties makes it a valuable ingredient in both dietary supplements and functional products. With proper storage and handling, Fisetin can be effectively utilized to promote health, enhance cognitive function, and support long-term well-being
