Product Name:Ginsenoside RG3 Powder
Botanical Source:Panax Ginseng C.A. Meyer
Part Used: Stem & Leaf
CAS NO.:14197-60-5
Color:Light yellow to yellowish brown powder
Specification:1%-10% Ginsenoside Rg3
Particle Size: 100% pass 80 mesh
GMO Status:GMO Free
Packing: in 25kgs fiber drums
Storage:Keep container unopened in cool, dry place,Keep away from strong light
Shelf Life:24 months from date of production
Product Overview
Ginsenoside Rg3 is a major active component of ginseng (Panax spp.) and is widely recognized for its diverse biological activities. It is a natural triterpenoid saponin with significant pharmacological potential, including anti-cancer, anti-inflammatory, and antioxidant properties .
As a key ingredient in ginseng, Ginsenoside Rg3 is primarily used in scientific research for its therapeutic applications in various fields such as cancer treatment, metabolic disorders, and neurodegenerative diseases. It is also employed in the development of pharmaceuticals and nutraceuticals due to its high purity and stability .
Key Features and Applications
- Anti-Cancer Activity
Ginsenoside Rg3 has been shown to inhibit tumor cell metastasis by blocking the adhesion and invasion of cancer cells. It also exhibits anti-angiogenesis activity, which is crucial in preventing the spread of tumors . - Metabolic Regulation
Studies have demonstrated that Ginsenoside Rg3 can improve insulin sensitivity and reduce hepatic steatosis in high-fat diet-induced obesity models. It modulates the STAT5-PPARγ pathway, which plays a key role in lipid metabolism and adipogenesis . - Neuroprotective Effects
Research indicates that Ginsenoside Rg3 can restore mitochondrial cardiolipin homeostasis, which is beneficial in the prevention and treatment of Parkinson’s disease . - Anti-Inflammatory and Antioxidant Properties
Ginsenoside Rg3 exhibits strong anti-inflammatory and antioxidant effects, making it a valuable candidate for the treatment of inflammatory and oxidative stress-related diseases .
Solubility and Stability
- Solubility:
- DMSO: ≥5 mM
- Ethanol: ≥10 mg/mL
- Water: Slightly soluble
- Stability:
- Ginsenoside Rg3 is stable under appropriate storage conditions. When stored at 2–8°C, it remains stable for up to 12 months .
- When dissolved in DMSO, it should be used immediately after dilution to maintain its potency .
Safety and Usage Notes
- Usage Restriction:
Ginsenoside Rg3 is strictly for research use only and is not intended for clinical medical applications or human consumption . - Handling Instructions:
- Always prepare and use solutions on the same day to avoid degradation.
- Allow the product to equilibrate to room temperature for at least 1 hour before use .
- Avoid repeated freezing and thawing of stock solutions to preserve product integrity .
Product Specifications
| Parameter | Specification |
|---|---|
| Product Name | Ginsenoside Rg3 |
| CAS Number | 14197-60-5 |
| Molecular Formula | C₄₂H₇₂O₁₃ |
| Molecular Weight | 785.01 |
| Purity | ≥98% (HPLC) |
| Appearance | White to off-white powder |
| Storage | 2–8°C (sealed, away from light); -80°C for 1 year in solution |
| Solubility | DMSO: ≥5 mM; Ethanol: ≥10 mg/mL |
| Source | Panax spp. |
| Usage | Research use only (not for diagnostic or clinical purposes) |
Conclusion
Ginsenoside Rg3 is a highly potent and versatile compound with a wide range of biological activities. Its unique chemical structure and diverse therapeutic applications make it a valuable tool in both basic and applied research. With proper handling and storage, Ginsenoside Rg3 can be effectively utilized in various scientific studies and drug development projects.
