Product Name:Ginsenoside RG3 Powder
Botanical Source:Panax Ginseng C.A. Meyer
Part Used: Stem & Leaf
CAS NO.:14197-60-5
Color:Light yellow to yellowish brown powder
Specification:1%-10% Ginsenoside Rg3
Particle Size: 100% pass 80 mesh
GMO Status:GMO Free
Packing: in 25kgs fiber drums
Storage:Keep container unopened in cool, dry place,Keep away from strong light
Shelf Life:24 months from date of production
Ginsenoside Rg3 is a natural triterpenoid saponin derived from Panax ginseng (ginseng), a traditional herb widely used in both Eastern and Western medicine. It is known for its diverse biological activities and has been extensively studied in research related to neuroprotection, anti-inflammatory effects, and cancer prevention. This product is supplied as a white to off-white powder, with high purity and consistent quality, suitable for laboratory research and pharmaceutical development.
Key Features
- Chemical Name: (20R)-Ginsenoside Rg3
- CAS Number: 38243-03-7
- Molecular Formula: C₄₂H₇₂O₁₃
- Molecular Weight: 785.01 g/mol
- Purity: ≥98% (HPLC)
- Appearance: White to off-white powder
- Solubility: Sparingly soluble in water; soluble in DMSO, ethanol, and methanol
- Storage Conditions: Store at -20°C in a sealed container, away from light and moisture. For short-term storage, 2–8°C is acceptable.
- Shelf Life: ≥12 months when stored properly
Biological Activities and Applications
Ginsenoside Rg3 has been shown to possess a wide range of pharmacological activities, making it a valuable compound in biomedical research. Some of its key applications include:
- Neuroprotection: Ginsenoside Rg3 exerts neuroprotective effects on hippocampal neurons, potentially through the modulation of NMDA receptors and other signaling pathways .
- Anti-inflammatory and Antioxidant Effects: It inhibits JNK-mediated NF-κB activation and reduces oxidative stress in various models of ischemic injury and myocardial infarction .
- Cancer Prevention and Treatment: Studies have demonstrated that Ginsenoside Rg3 can inhibit tumor growth and promote apoptosis in cancer cells, particularly in glioblastoma and hepatocellular carcinoma . It may also enhance the efficacy of radiotherapy and chemotherapy .
- Metabolic Regulation: Ginsenoside Rg3 has been shown to improve glucose metabolism and reduce fasting blood glucose levels in diabetic mice, suggesting its potential in diabetes management .
- Cardiovascular Protection: It mitigates isoproterenol-induced myocardial injury and improves heart function through antioxidant mechanisms .
- Anti-cancer Nanoparticle Formulations: Ginsenoside Rg3-loaded nanoparticles (Rg3-NPs) have been developed to improve bioavailability and therapeutic effects in cancer treatment .
Usage and Handling
- Dissolution: Ginsenoside Rg3 is best dissolved in DMSO or other organic solvents for immediate use in experiments. For aqueous solutions, it can be diluted into PBS or isotonic saline, but not recommended for long-term storage .
- Storage: Always store the product at -20°C in a sealed container to maintain stability and prevent degradation. Avoid exposure to light and air.
- Safety: This product is for research use only and is not intended for human or animal consumption. Follow all safety guidelines when handling chemical compounds.
Packaging Options
We offer a variety of packaging sizes to meet different research needs:
- 5 mg, 10 mg, 20 mg, 50 mg, 100 mg, 1 g, 100 g
- Customized packaging available upon request
Quality Control and Compliance
- Purity Analysis: Performed using High-Performance Liquid Chromatography (HPLC) to ensure ≥98% purity.
- Certificate of Analysis (CoA): Provided with each batch to confirm product specifications and compliance with international standards.
- Regulatory Compliance: This product is compliant with FDA, EMA, and ICH guidelines for chemical reagents used in pharmaceutical research.
Keywords
- Ginsenoside Rg3 powder
- (20R)-Ginsenoside Rg3
- Natural triterpenoid saponin
- Ginseng extract
- Biological activity of Ginsenoside Rg3
- Cancer research
- Neuroprotection
- Anti-inflammatory
- Pharmaceutical grade
- HPLC purity
Conclusion
Ginsenoside Rg3 is a promising natural compound with broad applications in biomedical research. Its high purity, consistent quality, and well-documented biological activities make it an ideal choice for researchers in pharmacology, oncology, and neuroscience. By optimizing the product description with relevant keywords and emphasizing its scientific value, this product is well-positioned to attract a global audience, especially in the European and American markets.
