Wahi a Wikipedia, ʻo ka inoa IUPAC o ka piperlongumine ʻo 1-[(2E) -3-(3,4,5-Trimethoxyphenyl) prop-2-enoyl] -5,6-dihydropyridin-2(1H)-one, a me kekahi. makemake nā pūnaewele e hoʻohana i ka 5,6-dihydro-1-[(2E) -1-oxo-3-(3,4,5-trimethoxyphenyl) -2-propenyl] -2 (1H) -pyridinone.
He lōʻihi loa ka inoa kemika piha o ka piperlongumine a ʻaʻole hiki i nā kānaka ke hoʻomanaʻo, no laila hoʻohana nā mea noiʻi i ka piplartine a i ʻole ka piperlongumine i ka hapa nui o nā palapala ʻepekema.A ʻo 20069-09-4 kāna helu helu CAS.
Inoa mea kūʻai:Piperlongumine pauda
Inoa ʻē aʻe: Piplartin,Piperlongumineextract, Piplartine, 5,6-Dihydro-1-[(2E)-1-oxo-3-(3,4,5-trimethoxyphenyl)-2-propen-1-yl]-2(1H)-pyridinone,PPLGM , ʻO ka pauka pippali, ʻO Piper Longum extract
CAS Nhelu: 20069-09-4
Puna Hua:Piper Longum Linn
ʻIke: 98% min
Laʻana manuahi: Loaʻa
Nānā: ʻO ka pauka kristal keʻokeʻo
Pono: Anti-cancer, anti-aging, senolytic
Ke ola papa: 2 makahiki
PiperlongumineLoaʻa ka nui ma Piper longum, kahi mea kanu no ka ʻAsia Hema.ʻO India a me Kina nā ʻāina nui ʻelua e kūʻai aku ana i nā pauka Piper longum a me nā mea hoʻohui ma Amazon a me nā pūnaewele e-commerce ʻē aʻe.
ʻIke ʻia ʻo Piper longum he pepa lōʻihi a i ʻole pippali ma India.Aia ka Piper longum i nā alkaloids, amides, Lignans, Esters, nā aila volatile, etc.
Ua hoʻohana ʻia ka hua Piper longum i ka ʻōnaehana Ayurvedic o ka lāʻau lapaʻau a me nā lāʻau lapaʻau Kuʻuna Kina no ka manawa lōʻihi loa.
Piperlongumine kiko'ī
ʻAʻohe pauka piperlongumine nui ma ka mākeke.ʻO ka hapa nui o nā mea hoʻolako he hui reagent, a no ka noiʻi wale nō kā lākou huahana.Eia kekahi, ʻo kā lākou nui he 10mg wale nō i 500mg i loko o kahi hue liʻiliʻi loa.
Aia nā ʻāpana o ka lāʻau piper longum, me nā kikoʻī kaulana e like me 4:1, 10:1, 20:1, etc.
ʻO nā huahana lāʻau India i loaʻa i ka piperlongumine ka hapa nui o ka ratio extract.Ehia mau pipelongumines i loko?ʻAʻohe mea ʻike.Hiki ke ana 'ia ka piperlongumine ma'amau mai ka piper longumine.
ʻO ka kikoʻī he 98% min.
Inā he nīnau kāu, e ʻoluʻolu e hoʻokaʻaʻike mai iā mākou no nā kikoʻī hou aku.
Piperlongumine solubility
ʻAʻole hiki ke hoʻoheheʻe ʻia ka Piperlongumine i ka wai.No laila, inā makemake ʻoe e hoʻohana piha i ka piperlongumine supplements, pono ʻoe e hana i ka piperlongumine ma nā ʻano o nā capsules ma kahi o nā piperlongumine papa a i ʻole nā pauka.
Hiki ke hoʻoheheʻe ʻia ka Piperlongumine i nā mea hoʻoheheʻe kūlohelohe e like me ka ethanol, DMSO, a me dimethylformamide (DMF).
Mechanism of Action of Piperlongumine
Pono o Piperlongumine
Ma ke ʻano he lāʻau lapaʻau maʻamau i hoʻohana ʻia ma Kina a me India, ua hōʻike ʻia ka mea kanu piper longum he tonic hanu, a maikaʻi hoʻi no ka ʻai ʻana maikaʻi a me ka ʻōnaehana pale.
No ka piperlongumine pono'ī, ʻo ka anti-cancer a me ka anti-aging nā mea nui ʻelua.
ʻO Piperlongumine no ka anti-aging (senolytic)
ʻO Piperlongumine kahi mea hana senolytic hou.Inā makemake ʻoe e ʻike pehea e hana ai ka piperlongumine no ka anti-aging, pono ʻoe e ʻike mua i nā cell senescent.
He kuleana koʻikoʻi nā cell Senescent i nā maʻi pili makahiki.Hiki iā mākou ke ʻōlelo ʻo ke kumu o ka ʻelemakule nā cell senescent.
A laila pehea e hoʻoponopono ai i kēia mau maʻi?ʻO ke ala maʻalahi loa ka pepehi ʻana i kēia mau cell senescent!ʻO nā pūnaewele Senescent he mau mea momona momona e hōʻiliʻili me ka makahiki ma nā ʻiʻo a me nā ʻāpana o kou kino.Hoʻokomo ʻo Piperlongumine i ka apoptosis i nā cell senescent a pepehi iā lākou ma o kahi mīkini kūʻokoʻa ROS.
Hiki i ka Piperlongumine ke hoʻolohi i ka hoʻokumu ʻana o nā cell senescent, koho i ka luku ʻana i nā cell senescent a hoʻōla i kou olakino.Hana maikaʻi ia me nā mea ʻē aʻe anti-aging, e like me pterostilbene, resveratrol, fisetin, etc.
nā hoʻokolohua hoʻokolohua pipelongumine
Ua aʻo nui ʻia ʻo Piperlongumine i ka mālama ʻana i ka maʻi kanesa e piʻi ana i nā hoʻokolohua lapaʻau.Mai ka hōʻike mua e pili ana i kona hoʻohana ʻana i ka noiʻi maʻi maʻi (ma 2011) ma kahi o 80 mau pepa i paʻi ʻia ma lalo o 10 mau makahiki, akā aia nō kahi āpau.ʻAʻohe haʻawina metabolism o ka piperlongumine i loko o ke kino kanaka.
Nā hopena ʻaoʻao o Piperlongumine
ʻAʻole hōʻike ʻia nā hopena ʻino.
