Dihydromyricetin 98%

Dihydromyricetin , also know as Ampelopsin, is a flavanonol, a type of flavonoid. It is found in the Ampelopsis species japonica, megalophylla, and grossedentata; Cercidiphyllum japonicum; Hovenia dulcis; Rhododendron cinnabarinum; some Pinus species; and some Cedrus species, as well as in Salix sachalinensis.

Hovenia dulcis twb tau muab siv nyob rau hauv tsoos suav tshuaj kho kub taub hau, cab kab mob no, raws li ib tug laxative, thiab ib tug kev kho mob ntawm daim siab kab mob, thiab raws li ib tug hangover kev kho mob. Txoj kev muaj tau tsim los extract ampelopsin los ntawm nws nyob rau loj dos.

In a trail of sixty patients with fatty liver disease dihydromyricetin improved glucose and lipid metabolism and exerted anti-inflammatory effects which were beneficial.Vine tea extract dihydromyricetin powder is extracted from the stems and leaves of Ampelopsis Grossedentata (commonly called vine tea). Dihydromyricetin has antioxidant, alcohol anti-intoxicant, anti-inflammatory and anticancer properties, it is also helpful for scavenging free radicals, protecting liver function and regulating blood sugar and blood fat. Vine tea extract dihydromyricetin is mainly used in liver protection and alcohol anti-intoxicant supplements and skin care products.Vine tea, also be called as Cany tea or Ampelopsin.Dihydromyricetin is extracted from the young stem and leaf of Cany tea (Ampelopsin) Researches show than vine tea can relieve inflammatory, mixture cough and antitussives, it also has strong inhibitory effect to common bacteria can be found in food.Some of flavonoids, for example Ampelopsin and Dihydromyricetin, are main active ingredients in vine tea,which have almost same MIC and MBC comparing with berberine, and have high Free radical scavenging activity varies between 73.3~91.5 %. It can also reduce oxidative damage in the body, anti-aging, reduce the deformation and tissue necrosis of animal liver.Dihydromyricetin also have ability on lifting alcohol poisoning, prevent for AFL, inhibit the deterioration of liver cells, decrease the incidence of liver cancer. In these case Dihydromyricetin is consider as a good product for enhance activity of SOD, protecting liver and removing inebriation.
Dihydromyricetin tam sim no nkag mus soj ntsuam raws li ib tug hauv chav kawm ntawv ntawm cov tshuaj tshiab thaum soj ntsuam ntawm Dihydromyricetin tiav ib tug loj txhob nyob rau hauv teb ntawm anti-leukemia thiab tshuaj ntawm Nasopharyngeal cancer.

Khoom npe: Dihydromyricetin  98%

specification:98% los ntawm HPLC

Botanic Source: Hovenia dulcis

CAS Tsis: 200-001-8

Tsob nroj Part Siv: Tawv

Xim: dawb cov hmoov zoo nrog cov yam ntxwv tsw thiab saj

GMO raws li txoj cai: GMO Dawb

Packing: in 25 kgs fiber drums

Cia: Khaws thawv uas tsis tau qheb nyob rau hauv txias, qhuav qhov chaw, Cia deb ntawm muaj zog teeb

Txee lub neej: 24 lub hlis ntawm hnub uas ntau lawm

Most people who drink alcohol know the pain of hangover: headache, dizziness, fatigue, nausea, stomach discomfort, sleepiness, sweating, thirst, and cognition.

Here is a dietary supplement that can greatly alleviate your hangover, not only let you feel the beauty of the wine, vodka, rum, and whiskey but not be afraid of the discomfort caused by excessive drinking.

This is Dihydromyricetin powder(DHM), a natural gift from the ancient oriental plant of vine tea.

What is dihydromyricetin (DHM)?

Dihydromyricetin, also known as snake glucose, is a particular flavonoid extracted from vine tea or Hovenia Dulcis.

DHM structural formula:

DHM’s physical and chemical properties:

White needle crystal, soluble in hot water, hot ethanol, and acetone, also soluble in ethanol and methanol, but rarely soluble in ethyl acetate, insoluble in chloroform, petroleum ether. Microherb studies have told that dihydromyricetin has excellent thermal stability, but irreversible oxidation occurs when dihydromyricetin is more than 100 °C. DHM is stable under neutral and acidic conditions.

These substances have many unique effects such as scavenging free radicals, anti-oxidation, anti-thrombosis, anti-tumor, anti-inflammatory, and so on. It is called unique because it has the following characteristics in addition to the general features of flavonoids:

1. The widespread flavonoids are insoluble in water, soluble in ethanol (alcohol), and DHM is readily soluble in hot water, which means that DHM in vine tea can be soaked out with boiling water and have more effective;
2. In addition to the action of general flavonoids, dihydromyricetin has the functions of relieving alcoholism, preventing alcoholic liver, and fatty liver, inhibiting the deterioration of liver cells, and reducing the incidence of liver cancer; it is a right product for protecting the liver and protecting liver and hangover.
3. Dihydromyricetin has a low molecular weight (320), which is easier to pass through the blood-brain barrier and has a fast onset.

What is vine tea extract?

Vine tea, commonly known as berry tea, is a wild vine belonging to the genus Vitis. It is not only a pure natural green drink but also a tea with potent medicinal properties. It is rich in flavonoids, amino acids, vitamins, and essential trace elements. It has the functions of softening blood vessels, sterilizing and anti-inflammatory, and long-term drinking can eliminate sub-health of the human body. It has been a history of folk drinking for thousands of years, and it has been cultivated for hundreds of years. For thousands of years, it was the favorite of the aristocrats the princes, and it was also the heart of the field farmer.

According to nutrition and tea experts, vine tea is rich in phytonutrients. Among them, dihydromyricetin has outstanding heat-clearing and detoxification, dilating throat, anti-bacterial and anti-inflammatory, anti-influenza hepatitis B virus and assists the “three high” prevention and treatment of cardiovascular and cerebrovascular diseases.

Vine tea extract VS Hovenia Dulcis extract

Hovenia Dulcis is not the major source of dihydromyricetin since it’s low in content and high in cost. Vine tea is the best choice.

How does DHM relieve drunkenness and hangovers?

DHM can enhance your body’s natural ability to break down alcohol, so you won’t have morning- fog and sleepiness when you wake up.

What is the relationship between alcohol breakdown and your second-day sensation?

An institution named “The National Institute of Alcohol Abuse and Alcoholism” has a lot of questions entitled < Alcohol Metabolism: A Update>.

The study describes the primary process of alcohol breakdown. We are here to summarize the necessary parts for you.

Two enzymes—alcohol dehydrogenase (ADH) and acetaldehyde dehydrogenase( ALDH)—help your body break down alcohol.

When you first start drinking, ADH breaks down alcohol to acetaldehyde, a highly toxic and carcinogenic substance.

Next, ALDH further metabolizes acetaldehyde into an acidic by-product called acetate, which is then broken down into the water and safely discharged from your body.

So why do you feel so uncomfortable in the morning after drinking the night of wine?

When you drink more than the amount of liver that can be broken down, the toxins caused by these alcohols will pile up and put a lot of pressure on your body.

The longer these toxins are in your body, the worse you will feel the next day before metabolism and safe excretion.

In other words, prolonged toxic substances are exposed in your body and can increase the sequelae of drinking.

DHM comes to the rescue!

This powerful flavonoid helps protect the liver (and your feelings the next day) by speeding up the metabolism of alcohol.

How do we know?

Studies have shown that Vine tea extract DHM can increase the activity of ADH and ALDH in the liver, allowing the body to metabolize and excrete alcohol and toxins more quickly.

Then you wake up and feel refreshed and ready for a new day!

How do DHM and alcohol affect the brain?

Alcohol has a lot of effects on the brain.

The first break breaks the delicate balance between the two neurotransmitters:

gamma-aminobutyric acid (GABA) and glutamate.

TIPs:

What is GABA?

GABA is a naturally occurring non-protein amino acid that is an important inhibitory neurotransmitter in the mammalian central nervous system. It plays an essential role in the human cerebral cortex, hippocampus, thalamus, basal ganglia and cerebellum, and has a regulating effect on various functions of the body. That is to say, when the body’s GABA deficiency, it will produce anxiety, anxiety, fatigue, anxiety and other emotions.

As an inhibitory neurotransmitter, GABA can effectively inhibit the excessive secretion of excitatory neurotransmitters such as dopamine, leaving people in a state of relaxation, lowering blood pressure, slowing heartbeat, and calming mood.

In other words, GABA is a substance that relaxes people’s minds and bodies.

When alcohol binds to the GABA receptor, it activates the GABA receptor, causing a high degree of relaxation, reduced inhibition, ambiguity, and loss of motor control.

This behavior makes the brain think that there is more GABA in the system than usual.

Then your body tries to reduce the GABA content to restore balance.

But the next morning when alcohol leaves your order, you may experience a rebound effect that can cause anxiety, difficulty sleeping, and lack of concentration.

DHM ensures that alcohol affects the brain’s GABA receptors as little as possible, so this reaction does not occur and you won’t experience rebound or hangover symptoms the next day.

DHM can accelerate the decomposition of acetaldehyde and protect the liver.

Dihydromyricetin is also difficult to support the liver to break down toxic chemical acetaldehyde as soon as possible.

When you drink alcohol, the body breaks it down into smaller chemicals until all the by-products have entirely disappeared.

However, one of the compounds is called acetaldehyde, which is 20 times more toxic than alcohol.

High concentrations of acetaldehyde in your system may cause some uncomfortable symptoms and increase hangover symptoms the next day.

When your body is full of acetaldehyde, your liver can only remove it quickly. However, DHM can help your body break down acetaldehyde faster, so you can get back to regular faster.

When should I take it, before or after drinking?

When you take dihydromyricetin, it depends on the task you are trying to accomplish.

Thus, for example, the researchers found that taking a relatively large dose before drinking alcohol reduced the level of alcohol in the blood by 55%.

However, for most people, we recommend making it immediately after drinking, which is an excellent way to reduce the hangover symptoms that are usually felt the next day.

Taking DHM after drinking alcohol can also block the GABA rebound effect, regularly awakening you in the middle of the night, or anxious about you the next day.

So taking DHM immediately after drinking means that the adverse effects of alcohol will diminish.

Is dihydromyricetin effective and what is the best dosage?

Yes. There is sufficient scientific evidence to suggest that dihydromyricetin is effective in reducing the effects of poisoning and reducing hangovers and supporting the liver.

The real question is, what is the most suitable dose?

An alcohol extract of 125 mg/kg body weight has been used in capable rats, which translates to an estimated human dosage of 9-9.3 mg/lbs human weight,

equals to:

1, 400mg for a 150lb person

2, 800mg for a 200lb person

3, 1200mg for a 250lb people

These are the estimated human maximum doses based on rat studies.

However, the following factors should be considered when using the dosage:

The number of alcoholic beverages you have ever eaten

The alcohol content in the beverage is exhausted

How fast do you drink?

Have you ever eaten?

In reality, it also depends on what you want to achieve with DHM because the dose required to reduce poisoning is much higher than the dose after drinking to eliminate hangovers.

Supplements containing dihydromyricetin:

Tso cai:

1) tshem cov dawb radical nyob rau hauv lub cev thiab antioxidation: Lub hmab tshuaj yej extract yuav zoo theem cia rau hauv lipid peroxidation. Nws muaj peev xwm tiv thaiv kom txhob oxidative kev puas tsuaj ntawm antioxidase nyob rau hauv lub cev los ntawm cov dawb radical. Ces nws yuav ua tau kom lub oxidation kuj ntawm tus tib neeg lub cev;
2) cov tshuaj tua kab Action: Lub hmab tshuaj yej extract muaj lub muaj zog inhibitory kev txiav txim ntawm Staphylococcus aureus thiab Bacillus subtilis. Nws kuj muaj inhibitory kev txiav txim ntawm Aspergillus flavus, Aspergillus niger, penicillium thiab Alternaria. Dihydromyricetin muaj inhibitory kev txiav txim ntawm Staphylococcus aureus, Staphylococcus aureus (S. Aureus) thiab Pseudomonas aeruginosa.
3) Kev tiv thaiv hauv lub siab: Dihydromyricetin muaj lub muaj zog inhibitory kev txiav txim ntawm tus sawv ntawm ALT thiab AST nyob rau hauv cov ntshav ntshiab. Nws tau tsawg lub tag nrho bilirubin nyob rau hauv cov ntshav ntshiab. Yog li ntawd nws muaj lub muaj zog txiav txim oflowing lub aminotransferase thiab daj ntseg. Lub hmab tshuaj yej extract yuav tswj yus tus kheej lub siab fibrosis nyob rau hauv lub nas.
4) Txo cov theem ntawm cov ntshav qab zib thiab ntshav muaj roj: Dihydromyricetin yuav txo tau cov ntshav muaj roj ntau ntau nyob hauv nas. Nws muaj peev xwm txo tau cov kev puas tsuaj rau lub siab lub hlwb tshwm sim los ntawm cov ntshav muaj roj ntau ntau thiab txhim kho lub antioxidation muaj peev xwm. Nyob rau tib lub sij hawm, nws tau tsis muaj lub theem ntawm cov ntshav qab zib.
5) Anti o: Lub hmab tshuaj yej extract yuav zoo tswj yus tus kheej tus nas pinna o tshwm sim los ntawm xylene. Nws tseem yuav tswj yus tus kheej lub writhing teb nyob rau hauv lub nas tshwm sim los ntawm acetic acid.
6) Anti-mob: Lub hmab tshuaj yej extract muaj zoo tswj yus tus kheej mus cell loj hlob ntawm ib co mob hlwb.

Daim ntaub ntawv:

Tshuaj cov khoom:

Dihydromyricetin yog dav siv nyob rau hauv xws li anti-inflammatory, antitussive, expectorant, analgesic, antibacterial lam 1700ppm los yog ntau tshaj. Rau cov ntsiav tshuaj, tsiav tshuaj, granules, thiab lwm yam

Kev pab kho mob cov khoom:

Protect siab, hangover nyhuv. Leeb lub decomposition ntawm lub ethanol metabolite acetaldehyde. 100-800ppm

Ntshav qab zib txos, ntshav lipids 150-200ppm

Antioxidant, free radical qus 400ppm

DMY yuav ho inhibit qhov kev tsim ntawm MDA nyob rau hauv roj thiab Sibhawm, thiab nws muaj enhanced antioxidant kev ua si nrog kev coj dawb huv; nws muaj muaj zog antioxidant nyhuv rau cov tsiaj roj thiab zaub roj.

Ob peb raw khoom xa khoom raws li mov kev ruaj siab.Muaj zog Cooperative Institutions los pab txhawbLub koom haum ntawm botany / Institution ntawm microbiology / Academy of Science thiab Technology / University