Product Name: Icaritin
English Name: Icaritin
Latin Name: Epimedium brevicornu Maxim.
CAS Number: 118525-40-9
Molecular Formula: C₂₁H₂₀O₆
Molecular Weight: 368.38
Purity: ≥98% (HPLC)
Appearance: Light yellow powder
Solubility: Soluble in methanol, ethanol, DMSO, and other organic solvents; insoluble in chloroform, ether, and benzene.
Storage Conditions:
- Powder: -20°C for 3 years
- In solvent: -80°C for 1 year
Product Overview
Icaritin is a natural flavonoid compound derived from the dried leaves of Epimedium brevicornu Maxim., a traditional Chinese medicinal herb commonly known as “horny goat weed.” It is widely recognized for its diverse biological activities, including anti-inflammatory, immunomodulatory, and anti-cancer properties. Icaritin is a key component in the development of modern pharmaceuticals and nutraceuticals, particularly in the fields of oncology, men’s health, and bone health .
Key Features and Advantages
- High Purity and Quality Control
Icaritin is produced using a robust extraction and purification process, ensuring a purity of ≥98% as verified by High-Performance Liquid Chromatography (HPLC). The product is free from impurities and contaminants, meeting strict pharmaceutical and research-grade standards . - Diverse Biological Activities
- Anti-Cancer Effects: Icaritin has been shown to inhibit the growth of various cancer cells, including hepatocellular carcinoma (HCC), prostate cancer, and multiple myeloma. It exerts its anti-tumor activity by inducing cell cycle arrest, apoptosis, and the inhibition of key signaling pathways such as IL-6/JAK2/STAT3 .

- Immune Regulation: Icaritin modulates immune-related signaling pathways, enhancing immune function and exhibiting anti-inflammatory properties .
- Cardiovascular and Hormonal Effects: It has been reported to improve cardiovascular function and exhibit hormone-regulating activity, making it beneficial for men’s health and sexual wellness .
- Neuroprotection and Bone Health: Icaritin has neuroprotective effects against beta-amyloid-induced neurotoxicity and is used in the prevention and treatment of osteoporosis .
- Anti-Cancer Effects: Icaritin has been shown to inhibit the growth of various cancer cells, including hepatocellular carcinoma (HCC), prostate cancer, and multiple myeloma. It exerts its anti-tumor activity by inducing cell cycle arrest, apoptosis, and the inhibition of key signaling pathways such as IL-6/JAK2/STAT3 .
- Modern Applications and Research
Icaritin is an innovative small molecule immunomodulatory ingredient developed through modern biotechnology. It has been conditionally approved by the State Drug Administration (NMPA) for the marketing of Acoradin (Epimedium Soft Capsules) in 2022 . Additionally, it is being explored for its potential in Alzheimer’s disease, anti-fatigue, anti-depression, and in vitro anti-SIV/HIV applications . - Comprehensive Support and Services
Our company provides value-added services such as document support, payment negotiation, and market trend analysis to help customers understand the latest product trends and industry developments . We also offer direct factory supply to ensure maximum cost-effectiveness and quality .
Safety and Dosage
According to the 2015 Chinese Pharmacopoeia, the safe daily dosage for adults is no more than 100 mg per day. Icaritin is generally well-tolerated, with minimal side effects reported in clinical studies .
Applications
- Pharmaceutical Research: Icaritin is used in the development of novel therapeutics for cancer, immunology, and neurodegenerative diseases.
- Nutraceuticals and Dietary Supplements: It is incorporated into products for kidney tonification, sexual enhancement, and bone health.
- Cosmetics and Personal Care: Due to its hormone-regulating and anti-inflammatory properties, Icaritin is used in formulations for men’s health and skincare.
- Biomedical Research: It is widely used in in vitro and in vivo studies to investigate its effects on cell proliferation, apoptosis, and signaling pathways
Conclusion
Icaritin is a versatile and highly potent compound with a wide range of applications in both traditional and modern medicine. Its high purity, diverse biological activities, and extensive research support make it a valuable ingredient for pharmaceutical, nutraceutical, and biomedical industries. With our commitment to quality, innovation, and customer service, we are dedicated to providing the best possible solutions for Icaritin-related products and services.







