ジヒドロミリセチン98％

ジヒドロミリセチンは、, also know as Ampelopsin, is a flavanonol, a type of flavonoid. It is found in the Ampelopsis species japonica, megalophylla, and grossedentata; Cercidiphyllum japonicum; Hovenia dulcis; Rhododendron cinnabarinum; some Pinus species; and some Cedrus species, as well as in Salix sachalinensis.

Hoveniaは御馳走熱、寄生虫感染、下剤として、および肝疾患の治療に漢方薬で使用され、二日酔いの治療などされていますdulcis。 方法は、大規模なスケールでそれからアンペロプシンを抽出するために開発されています。

In a trail of sixty patients with fatty liver disease dihydromyricetin improved glucose and lipid metabolism and exerted anti-inflammatory effects which were beneficial.Vine tea extract dihydromyricetin powder is extracted from the stems and leaves of Ampelopsis Grossedentata (commonly called vine tea). ジヒドロミリセチンは、 has antioxidant, alcohol anti-intoxicant, anti-inflammatory and anticancer properties, it is also helpful for scavenging free radicals, protecting liver function and regulating blood sugar and blood fat. Vine tea extract dihydromyricetin is mainly used in liver protection and alcohol anti-intoxicant supplements and skin care products.Vine tea, also be called as Cany tea or Ampelopsin.Dihydromyricetin is extracted from the young stem and leaf of Cany tea (Ampelopsin) Researches show than vine tea can relieve inflammatory, mixture cough and antitussives, it also has strong inhibitory effect to common bacteria can be found in food.Some of flavonoids, for example Ampelopsin and Dihydromyricetin, are main active ingredients in vine tea,which have almost same MIC and MBC comparing with berberine, and have high Free radical scavenging activity varies between 73.3~91.5 %. It can also reduce oxidative damage in the body, anti-aging, reduce the deformation and tissue necrosis of animal liver.Dihydromyricetin also have ability on lifting alcohol poisoning, prevent for AFL, inhibit the deterioration of liver cells, decrease the incidence of liver cancer. In these case Dihydromyricetin is consider as a good product for enhance activity of SOD, protecting liver and removing inebriation.
ジヒドロミリセチンの研究者は、鼻咽頭癌の抗白血病および医学の分野で画期的な成果を達成したときジヒドロミリセチンは現在、新薬のクラスとして臨床試験に入りました。

製品名：ジヒドロミリセチン 98%

仕様：98％HPLCによる

植物出典：ケンポナシ

CAS番号：200-001-8

植物部分は、使用される：バーク

カラー：特有の匂いと味と白の微粉末

GMOステータス：GMOフリー

パッキング：25kgsファイバードラムに

ストレージ：強い光から遠ざけること、涼しい、乾燥した場所に未開封の容器を保管してください

賞味期限：製造日から24ヶ月

Most people who drink alcohol know the pain of hangover: headache, dizziness, fatigue, nausea, stomach discomfort, sleepiness, sweating, thirst, and cognition.

Here is a dietary supplement that can greatly alleviate your hangover, not only let you feel the beauty of the wine, vodka, rum, and whiskey but not be afraid of the discomfort caused by excessive drinking.

This is Dihydromyricetin powder(DHM), a natural gift from the ancient oriental plant of vine tea.

What is dihydromyricetin (DHM)?

Dihydromyricetin, also known as snake glucose, is a particular flavonoid extracted from vine tea or Hovenia Dulcis.

DHM structural formula:

DHM’s physical and chemical properties:

White needle crystal, soluble in hot water, hot ethanol, and acetone, also soluble in ethanol and methanol, but rarely soluble in ethyl acetate, insoluble in chloroform, petroleum ether. Microherb studies have told that dihydromyricetin has excellent thermal stability, but irreversible oxidation occurs when dihydromyricetin is more than 100 °C. DHM is stable under neutral and acidic conditions.

These substances have many unique effects such as scavenging free radicals, anti-oxidation, anti-thrombosis, anti-tumor, anti-inflammatory, and so on. It is called unique because it has the following characteristics in addition to the general features of flavonoids:

1. The widespread flavonoids are insoluble in water, soluble in ethanol (alcohol), and DHM is readily soluble in hot water, which means that DHM in vine tea can be soaked out with boiling water and have more effective;
2. In addition to the action of general flavonoids, dihydromyricetin has the functions of relieving alcoholism, preventing alcoholic liver, and fatty liver, inhibiting the deterioration of liver cells, and reducing the incidence of liver cancer; it is a right product for protecting the liver and protecting liver and hangover.
3. Dihydromyricetin has a low molecular weight (320), which is easier to pass through the blood-brain barrier and has a fast onset.

What is vine tea extract?

Vine tea, commonly known as berry tea, is a wild vine belonging to the genus Vitis. It is not only a pure natural green drink but also a tea with potent medicinal properties. It is rich in flavonoids, amino acids, vitamins, and essential trace elements. It has the functions of softening blood vessels, sterilizing and anti-inflammatory, and long-term drinking can eliminate sub-health of the human body. It has been a history of folk drinking for thousands of years, and it has been cultivated for hundreds of years. For thousands of years, it was the favorite of the aristocrats the princes, and it was also the heart of the field farmer.

According to nutrition and tea experts, vine tea is rich in phytonutrients. Among them, dihydromyricetin has outstanding heat-clearing and detoxification, dilating throat, anti-bacterial and anti-inflammatory, anti-influenza hepatitis B virus and assists the “three high” prevention and treatment of cardiovascular and cerebrovascular diseases.

Vine tea extract VS Hovenia Dulcis extract

Hovenia Dulcis is not the major source of dihydromyricetin since it’s low in content and high in cost. Vine tea is the best choice.

How does DHM relieve drunkenness and hangovers?

DHM can enhance your body’s natural ability to break down alcohol, so you won’t have morning- fog and sleepiness when you wake up.

What is the relationship between alcohol breakdown and your second-day sensation?

An institution named “The National Institute of Alcohol Abuse and Alcoholism” has a lot of questions entitled < Alcohol Metabolism: A Update>.

The study describes the primary process of alcohol breakdown. We are here to summarize the necessary parts for you.

Two enzymes—alcohol dehydrogenase (ADH) and acetaldehyde dehydrogenase( ALDH)—help your body break down alcohol.

When you first start drinking, ADH breaks down alcohol to acetaldehyde, a highly toxic and carcinogenic substance.

Next, ALDH further metabolizes acetaldehyde into an acidic by-product called acetate, which is then broken down into the water and safely discharged from your body.

So why do you feel so uncomfortable in the morning after drinking the night of wine?

When you drink more than the amount of liver that can be broken down, the toxins caused by these alcohols will pile up and put a lot of pressure on your body.

The longer these toxins are in your body, the worse you will feel the next day before metabolism and safe excretion.

In other words, prolonged toxic substances are exposed in your body and can increase the sequelae of drinking.

DHM comes to the rescue!

This powerful flavonoid helps protect the liver (and your feelings the next day) by speeding up the metabolism of alcohol.

How do we know?

Studies have shown that Vine tea extract DHM can increase the activity of ADH and ALDH in the liver, allowing the body to metabolize and excrete alcohol and toxins more quickly.

Then you wake up and feel refreshed and ready for a new day!

How do DHM and alcohol affect the brain?

Alcohol has a lot of effects on the brain.

The first break breaks the delicate balance between the two neurotransmitters:

gamma-aminobutyric acid (GABA) and glutamate.

TIPs:

What is GABA?

GABA is a naturally occurring non-protein amino acid that is an important inhibitory neurotransmitter in the mammalian central nervous system. It plays an essential role in the human cerebral cortex, hippocampus, thalamus, basal ganglia and cerebellum, and has a regulating effect on various functions of the body. That is to say, when the body’s GABA deficiency, it will produce anxiety, anxiety, fatigue, anxiety and other emotions.

As an inhibitory neurotransmitter, GABA can effectively inhibit the excessive secretion of excitatory neurotransmitters such as dopamine, leaving people in a state of relaxation, lowering blood pressure, slowing heartbeat, and calming mood.

In other words, GABA is a substance that relaxes people’s minds and bodies.

When alcohol binds to the GABA receptor, it activates the GABA receptor, causing a high degree of relaxation, reduced inhibition, ambiguity, and loss of motor control.

This behavior makes the brain think that there is more GABA in the system than usual.

Then your body tries to reduce the GABA content to restore balance.

But the next morning when alcohol leaves your order, you may experience a rebound effect that can cause anxiety, difficulty sleeping, and lack of concentration.

DHM ensures that alcohol affects the brain’s GABA receptors as little as possible, so this reaction does not occur and you won’t experience rebound or hangover symptoms the next day.

DHM can accelerate the decomposition of acetaldehyde and protect the liver.

Dihydromyricetin is also difficult to support the liver to break down toxic chemical acetaldehyde as soon as possible.

When you drink alcohol, the body breaks it down into smaller chemicals until all the by-products have entirely disappeared.

However, one of the compounds is called acetaldehyde, which is 20 times more toxic than alcohol.

High concentrations of acetaldehyde in your system may cause some uncomfortable symptoms and increase hangover symptoms the next day.

When your body is full of acetaldehyde, your liver can only remove it quickly. However, DHM can help your body break down acetaldehyde faster, so you can get back to regular faster.

When should I take it, before or after drinking?

When you take dihydromyricetin, it depends on the task you are trying to accomplish.

Thus, for example, the researchers found that taking a relatively large dose before drinking alcohol reduced the level of alcohol in the blood by 55%.

However, for most people, we recommend making it immediately after drinking, which is an excellent way to reduce the hangover symptoms that are usually felt the next day.

Taking DHM after drinking alcohol can also block the GABA rebound effect, regularly awakening you in the middle of the night, or anxious about you the next day.

So taking DHM immediately after drinking means that the adverse effects of alcohol will diminish.

Is dihydromyricetin effective and what is the best dosage?

Yes. There is sufficient scientific evidence to suggest that dihydromyricetin is effective in reducing the effects of poisoning and reducing hangovers and supporting the liver.

The real question is, what is the most suitable dose?

An alcohol extract of 125 mg/kg body weight has been used in capable rats, which translates to an estimated human dosage of 9-9.3 mg/lbs human weight,

equals to:

1, 400mg for a 150lb person

2, 800mg for a 200lb person

3, 1200mg for a 250lb people

These are the estimated human maximum doses based on rat studies.

However, the following factors should be considered when using the dosage:

The number of alcoholic beverages you have ever eaten

The alcohol content in the beverage is exhausted

How fast do you drink?

Have you ever eaten?

In reality, it also depends on what you want to achieve with DHM because the dose required to reduce poisoning is much higher than the dose after drinking to eliminate hangovers.

Supplements containing dihydromyricetin:

関数：

1）体と抗酸化中のフリーラジカルを消去：脂質過酸化ダウンつる茶抽出物ができる効果的にレベル。 これは、フリーラジカルによって引き起こされる体内のantioxidaseの酸化的損傷を防止することができます。 それは人体の耐酸化性を向上させることができます。
2）抗生物質処置：つるの茶抽出物は、黄色ブドウ球菌と枯草菌の強力な抑制作用を有します。 また、アスペルギルス・フラバス、アスペルギルス・ニガー、ペニシリウムとルナリアの阻害作用を有します。 ジヒドロミリセチンは、黄色ブドウ球菌、黄色ブドウ球菌（Staphylococcus aureus）（S。アウレウス）および緑膿菌の阻害作用を有しています。
3）肝臓の保護：ジヒドロミリセチンは、血清中のALTおよびASTの上昇の強力な抑制作用を有します。 これは、血清中の総ビリルビンが低いことができます。 だから、アミノトランスフェラーゼと黄疸をoflowing強い作用を有します。 つるの茶抽出物は、ラットにおける肝線維化を抑制することができます。
4）血糖および血中脂肪のレベルを下げる：ジヒドロミリセチンは、マウスにおける血中脂肪レベルを低減することができます。 これは、高い血中脂肪レベルによって引き起こされる肝細胞へのダメージを減少させ、抗酸化能力を向上させることができます。 同時に、高血糖のレベルが低いことができます。
5）抗炎症：つるの茶抽出物を効果的にキシレンによって引き起こされる腫れマウス耳介を抑制することができます。 それはまた、酢酸によって引き起こされるマウスにおけるライジング反応を抑制することができます。
6）抗腫瘍：ブドウ茶抽出物は、効果的ないくつかの腫瘍細胞の細胞増殖を抑制しています。

アプリケーション：

医学の製品：

ジヒドロミリセチンが広く、抗炎症剤、鎮咳剤、去痰剤、鎮痛剤、抗菌性薬用1700ppm以上のように使用されます。 等、錠剤、カプセル剤、顆粒剤、用

ヘルスケア製品：

プロテクト肝臓、二日酔いの効果。 エタノール代謝物のアセトアルデヒドの分解を促進します。 100-800ppm

血糖低下、血中脂質150-200ppm

酸化防止剤、フリーラジカル捕捉400ppmの

DMYは大幅に油脂におけるMDAの形成を阻害することができ、それは純度の抗酸化活性が増強されています。 それは、動物油および植物油に強い抗酸化作用を持っています。

供給保証などのいくつかの原料サプライヤー。サポートへの強い協同機関科学の微生物学/アカデミーと技術/大学の植物学研究所/機関