Product Name: L-Theanine
CAS No.: 3081-61-6
Molecular Formula: C7H14N2O3
Molecular Weight: 174.2 g/mol
Appearance: White crystalline or crystalline powder
Solubility: Water-soluble (up to 150 mg/mL)
Purity: ≥98%
Physical and Chemical Properties
L-Theanine is a unique amino acid primarily found in green tea leaves. It is a non-proteinogenic amino acid and is responsible for the umami (savory) flavor of green tea. It is water-soluble and has a slightly sweet taste. It is also known for its ability to cross the blood-brain barrier and influence neurotransmitter activity .
Health Benefits and Applications
L-Theanine is widely recognized for its numerous health benefits, including:
- Stress Reduction and Relaxation
L-Theanine promotes a sense of calmness and reduces stress by increasing alpha brain waves and inhibiting the effects of excitatory brain chemicals like glutamate. Clinical studies have shown that L-Theanine supplementation can reduce subjective stress and lower salivary cortisol levels . It is also effective in improving sleep quality and reducing symptoms of anxiety and depression . - Cognitive Enhancement
When combined with caffeine, L-Theanine enhances focus, attention, and working memory. It is commonly used in functional beverages and supplements to improve cognitive performance . - Neuroprotective Effects
L-Theanine has been shown to protect neurons from oxidative stress and dopamine-induced neurotoxicity. It increases glutathione (GSH) levels in astrocytes, which helps protect dopaminergic neurons . - Cardiovascular Health
L-Theanine may help lower blood pressure and reduce the risk of cardiovascular disease . - Immune System Support
It strengthens the immune system and has anti-inflammatory and antimicrobial properties . - Anti-Tumor and Anti-Cancer Effects
L-Theanine can inhibit tumor cell growth by competing with glutamine for metabolic pathways and enhancing the effectiveness of anti-tumor drugs .
Usage and Dosage
- Recommended Dosage: 200–800 mg per day
- Forms: Available as a powder, capsules, or in functional beverages
- Applications: Used in dietary supplements, functional beverages, and research reagents
Safety and Regulatory Status
- GRAS Status: L-Theanine is generally recognized as safe (GRAS) by the U.S. Food and Drug Administration (FDA) .
- Adverse Effects: Generally well-tolerated, with no significant side effects reported at recommended doses .
- Precautions: Not for human use as a drug or household medicine; for research purposes only .
Storage and Handling
- Storage Conditions: Store at room temperature, away from light and moisture, in a sealed container .
- Handling: Avoid inhalation of dust; wear protective gloves and goggles when handling .
Product Specifications
- Product Number: MB3341, GK28, T106216, etc.
- Packaging: Available in 25g, 100g, or custom sizes
- Quality Standard: ≥98% purity
- Testing Methods: HPLC, UV-Vis, and other analytical techniques
Conclusion
L-Theanine is a versatile and beneficial compound with a wide range of health-promoting properties. Its natural origin, safety profile, and effectiveness in reducing stress, enhancing cognition, and supporting overall well-being make it a popular choice in both the food and pharmaceutical industries. Whether used in supplements, functional beverages, or research, L-Theanine continues to be a valuable component in promoting human health and wellness
