Melatonin is an indoleamine neurohormone found across plants and animals, produced endogenously from serotonin (5-HT) and secreted in animals as a regulatory signal for synchronization of the circadian rhythm and the sleep-wake cycle. The melatonin receptor system, consisting of the MEL-1A-R, MEL-1B-R, and MT3 subtypes, demonstrates particular plasticity and modularity – antagonists such as Luzindole (sc-202700) and 2-Phenylmelatonin (sc-203466) show modification of systemic responses to the Melatonin signal without impeding activation of the receptors by Melatonin. Powerful antioxidant activity is associated with Melatonin, and it is known to provide protection to lipids, proteins, and DNA against oxidative damage. Several antioxidant enzymes are shown to be upregulated by Melatonin, including glutathione peroxidase, superoxide dismutases, and catalase. Melatonin also scavenges free radicals as a terminal antioxidant, reacting to generate stable end products and terminate radical chain reactions. Free movement through the blood-brain barrier positions Melatonin as a particularly significant endogenous antioxidant. Melatonin is a rat NOS1 (nNOS) inhibitor. Melatonin is an activator of MEL-1A-R and MEL-1B-R.
Ingoa Hua: Melatonin
CAS No: 73-31-4
Whakauru: Melatonin 99% i te HPLC
Tae: atu-ma ki te puehu kōwhai marama ki kakara āhuatanga, me te reka
Tūnga koiora kua: koiora kua Free
Tarapēke: i roto i te 25kgs pahu muka
Storage: Kia mau ipu āu i raumati, wahi maroke, Puritia atu i te marama kaha
Shelf Life: 24 marama i te rā o te hanga
taumahi:
-Helps whakahaere atu hormones me mau tonu ūngeri circadian o te tinana
-Melatonin āwhina hoki paura whakahaere i te wā
-Melatonin tauturu paura whakatau
-Melatonin paura he kaha pānga antioxidant
-Release o hormones whakaputa uri wahine
Taupānga:
Kei te fakanatula hua paura -Melatonin i roto i te tinana i roto i te whakautu ki te perception o te marama
i -Melatonin paura kua whakamahia ki te noho ohoroa, whawhai jet takamuri, tiaki ngā pūtau i te kino noa-tuwhena, i näianei i te pūnaha ārai mate, te ārai mate pukupuku, me te whakawhānui i te ora.
