Product Name: Psoralea Corylifolia Extract 90%-99% Bakuchiol (HPLC Verified)
Latin Name: Psoralea corylifolia L.
Extraction Part: Seeds
CAS Number: 10309-37-2
Molecular Formula: C₁₈H₂₄O
Molecular Weight: 256.38 g/mol)
Product Description: Psoralea Corylifolia Extract
Product Name: Psoralea Corylifolia Extract
Alternative Name: Psoralea corylifolia Seed Extract / Bakuchiol Extract
Product Overview:
Psoralea Corylifolia (Psoralea corylifolia L.), commonly known as Bakuchiol, is a traditional medicinal plant native to Asia, particularly India and China. It belongs to the Fabaceae (Leguminosae) family and is widely used in both traditional and modern medicine for its diverse bioactive properties. The extract is derived from the dried mature fruits of P. corylifolia and is rich in compounds such as bakuchiol, corylin, isopsoralen, and psoralen, which contribute to its therapeutic effects.
Key Features and Applications
1. Biological and Medicinal Properties
- Antioxidant Activity:
Psoralea Corylifolia Extract is a potent antioxidant, capable of scavenging free radicals and protecting cells from oxidative stress . - Anti-inflammatory and Antimicrobial Effects:
The extract exhibits strong anti-inflammatory properties and has been shown to inhibit the growth of various oral pathogens, including Streptococcus mutans and Porphyromonas gingivalis . - Vasodilatory Effects:
Studies have demonstrated that the extract induces vasodilation in rat arteries through both endothelium-dependent and endothelium-independent mechanisms, involving the inhibition of TRPC3 channels and the elaboration of prostaglandins . - Bone Health and Osteoporosis Prevention:
The extract promotes bone formation and increases bone mineral density, making it a potential candidate for the prevention and treatment of osteoporosis . - Anti-cancer Potential:
Several compounds isolated from P. corylifolia, including bakuchiol, isobavachalcone, and psoralen, have shown anti-cancer activity by inhibiting tumor cell proliferation, inducing apoptosis, and suppressing metastasis . - Skin Health and Anti-aging:
The extract is also used in cosmetic formulations for its anti-aging properties, particularly in the treatment of wrinkles, skin sagging, and vitiligo. It enhances melanin production and supports skin regeneration .
Product Specifications
| Parameter | Specification |
|---|---|
| Source | Dried mature fruits of Psoralea corylifolia L. |
| Active Compound | Bakuchiol (≥ 1.0% or 3.0%, depending on formulation) |
| Purity | ≥ 98% (as per HPLC analysis) |
| Physical Form | Powder or Oil (e.g., PhytoRetinol™-3 and PhytoRetinol™-P1) |
| Solvents Used | Methanol, Ethyl Acetate, DMSO, Chloroform, etc. |
| Storage Conditions | 2–8°C, protected from light and air; refrigerated or frozen for long-term storage |
| Shelf Life | 2 years from manufacturing date (for oil-based products) |
Product Standards and Safety
- Quality Control:
The product is rigorously tested for purity, heavy metals, microbial load, and contaminants. For example, PhytoRetinol™-3 contains ≥ 3.0% bakuchiol and has a maximum acid value of 10 . - Safety and Toxicity:
The extract is generally considered safe for external use, with low cytotoxicity at concentrations up to 10 μM. However, oral use should be guided by a healthcare professional . - Regulatory Compliance:
The product meets FDA, ECOCERT, and ISO 9001:2015 standards for quality and safety .
Applications and Uses
- Pharmaceuticals:
Used in the development of anti-cancer drugs, anti-inflammatory agents, and bone-protective formulations . - Cosmetics and Skincare:
Incorporated into anti-aging serums, vitiligo treatments, and skin-repairing creams for its antioxidant, anti-inflammatory, and melanin-boosting properties . - Food and Functional Ingredients:
The PhytoRetinol™ series is formulated as a food-grade extract with anti-aging and skin-repairing benefits .
Conclusion
Psoralea Corylifolia Extract is a versatile and scientifically supported botanical compound with a wide range of medical, cosmetic, and functional applications. Its rich composition of bioactive compounds makes it a valuable ingredient in both traditional and modern medicine. Whether used for bone health, skin rejuvenation, or anti-cancer therapy, this extract offers a natural and effective solution backed by extensive research and clinical studies.
