10-Deacetylbaccatin III (10-DAB)

Maelezo Fupi:

10-Deacetylbaccatins ni mfululizo wa asili zinazohusiana kwa karibumisombo ya kikabonikutengwa na mti wa yew (GeneraKodi)10-Deacetylbaccatin III ni mtangulizi wa dawa ya kuzuia saratanidocetaxel(Taxotere).

10-deacetylbaccatin III 10-O-acetyltransferaseinabadilisha 10-deacetylbaccatin kuwabaccatin III:

 

10-Deacetylbaccatin III, pia inajulikana kama 10-DAB au 10-DAB III, ni misombo ya kikaboni ya asili inayohusiana kwa karibu iliyotengwa na sindano zilizokaushwa na matawi madogo ya mti wa yew wa Ulaya (Taxus baccata).10-Deacetylbaccatin III ni kitangulizi cha dawa ya kuzuia saratani docetaxel (Taxotere).pacitaxel (taxol);cabazitaxel.10-10-deacetylbaccatin III ilipatikana kwa kuchagua kuzuia ukuaji wa L. DONOVANI amastigoti ndani ya seli ndani ya J774 murine macrophages in vitro katika viwango vya nanomolar na thamani ya IC (50) ya 70 nM.


  • Bei ya FOB:US $ 0.5 - 2000 / KG
  • Kiasi kidogo cha Agizo:Kilo 1
  • Uwezo wa Ugavi:10000 KG / kwa Mwezi
  • Bandari:SHANGHAI/BEIJING
  • Masharti ya Malipo:L/C,D/A,D/P,T/T
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  • Maelezo ya Bidhaa

    Lebo za Bidhaa

    Jina la kemikali: 10-Deacetylbaccatin III

    Nambari ya CAS:

    32981-86-5

    Visawe:

    10-Desacetylbaccatin III;10β-Deacetylbaccatin III;(2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-(Acetyloxy)-12-(benzoyloxy)-1,2a,3,4,4a,6,9,10,11, 12,12a,12b-dodecahydro-4,6,9,11-tetrahydroxy-4a,8,13,13-tetramethyl-7,11-methano-5H-cyclodeca[3,4]benz[1,2-b] ng'ombe-5-moja;7,11-Methano-5H-cyclodeca[3,4]benz[1,2-b]oxet-5-one, 12b-(acetyloxy)-12-(benzoyloxy)-1,2a,3,4,4a, 6,9,10,11,12,12a,12b-dodecahydro-4,6,9,11-tetrahydroxy-4a,8,13,13-tetramethyl-, (2aR,4S,4aS,6R,9S,11S, 12S,12aR,12bS)-;(Docetaxel USP Uchafu);10-Deacetylbaccatin III;10-Deacetyl baccatin;(2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-1,2a,3,4,4a,6,9,10,11,12,12a, 12b-Dodecahydro-4,6, 9,11,12,12b-hexahydroxy-4a,8,13,13-tetramethyl-7,11-methano-5H-cyclodeca[3,4]benz[1,2-b]oxet-5-moja 12b-acetate , 12-benzoate (USP);

    Fomu ya Molekuli: C29H36O10
    Mwonekano: Nyeupe Imara
    Mol.Uzito: 544.6
    Hifadhi: Jokofu 2-8°C

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