Oleoylethanolamide(OEA)

Igama lomkhiqizo:  Oleoylethanolamide , N-Oleoylethanolamide , OEA
Okunye igama:  n- (2-hydroxyethyl) -9-Z-octadecenamide, ethanolamide N-oleoyl, Oleoyl monoethanolamide, 9-Octadecenamide, n- (2-hydroxyethyl) oleamide
CAS Ayikho:  111-58-0
Formular Yamamolekhula:  C ₂₀H ₃₉NO ₂
Yamamolekhula isisindo: 325,5
yokuncwaninga izinsimbi kanye namakhemikhali: 90%, 95%, 85% imiz
Ukubukeka: ukhilimu-anemibala powder

Oleoylethanolamide is something new to the nutritional market as a popular dietary supplement ingredient used in weight loss formulas. Many bodybuilding fans are discussing oleoylethanolamide on reddit and other social networking platforms.

Oleoylethanolamide kuyinto metabolite engokwemvelo oleic acid wenza emathunjini amancane ngaphakathi emzimbeni womuntu. It is ngokwemvelo occuring, kanye nochwepheshe basibiza ngokuthi "yisikhathi endogenous".

OEA is a natural regulator of appetite, weight and cholesterol. It is a natural metabolite that is made in small amounts in your small intestine. OEA helps regulate hunger, weight, body fat and cholesterol by binding to a receptor known as PPAR-Alpha (Peroxisome proliferator-activated receptor alpha). In essence, OEA increases the metabolism of body fat and tells your brain that you are full and it’s time to stop eating. OEA is also known to increase non-exercise related calorie expenditure.

Oleylethanolamide umlando

imisebenzi Oleoylethanolamide begazi Kwatholakala kudala njengoba engu-50 edlule. Ngaphambi 2001, kwakungekho ucwaningo kakhulu ku OEA. Nokho, ngalowo nyaka, abacwaningi-Spanish wadiliza lipid futhi wafundelwa obhakwe kanjani, lapho isetshenziswa kanye ukuthi lenzani. Bona ihlolwe umphumela OEA ebuchosheni (amagundane) ngokujova ke ngqo ventricles ingqondo. Bathola akunamthelela yokudla futhi waqinisekisa ukuthi OEA akaziphathi ubuchopho, kodwa kunalokho, kusungula isignali ahlukene esithinta indlala yokudla nokuziphatha.

Oleylethanolamide VS cannabinoid anandamide

Imiphumela OEA aqalwa wafunda ngoba abelana ukufana nomunye zamakhemikhali, a cannabinoid eyaziwa ngokuthi anandamide. Cannabinoids zihlobene isitshalo insangu, futhi anandamides ekhona isitshalo (nensangu) kungandisa ofisayo ukuba isidlo ngu nokucupha impendulo yokudla. Ngokusho Wikipedia, Oleoylethanolamide iyona Analogue monounsaturated we anandamide endocannabinoid. Nakuba OEA has a isakhiwo sazo sekhemikhali ethi ayifane naleyo anandamide, nemiphumela yayo yokudla nokuphathwa isisindo zihlukile. Ngokungafani anandamide, OEA izenzo ngokuzimela indlela cannabinoid, olawula umsebenzi PPAR-α ukuze sikhuthaze lipolysis.

Structures of various fatty-acid ethanolamides: oleoylethanolamide (OEA), palmitoylethanolamide (PEA) and anandamide (arachidonoylethanolamide, AEA). (Cima Science Co., Ltd is the only manufacturer of bulk raw materials of OEA, PEA and AEA in China, if you need sample and price quote, please drop us an email in the contact us page.)

OEA sibopha nge ziyezwana okusezingeni eliphezulu kuya peroxisome-proliferator-isebenze yokwamukela-a (PPAR-a), a yokwamukela enuzi ngokomthetho amahlangothi eziningana lipid umzimba.

imithombo yemvelo oleoylethanolamide

Oleoylethanolamide kuyinto metabolite engokwemvelo oleic acid. Ngakho-ke, ukudla containg oleic acid liwumthombo ngqo ka OEA.

Oleic acid amanoni oyinhloko zemifino amafutha ezifana omnqumo, canola nobhekilanga. Oleic acid kungabuye atholakala nut amafutha, inyama, yenkukhu, ushizi, njll

imithombo zokudla ocebile oleic acid zihlanganisa: Canola Oil, Olive Oil, Ukwatapheya Oil, Almond Oil, Ukwatapheya, High Oleic Safflower Oil

Ezinye amaqiniso mayelana Oleic Acid:

Omunye amafutha ezivamile e ubisi lwebele lomuntu

Utakhela 25% fat ubisi cow sika

Monounsaturated

Omega-9 okunamafutha acid

Chemical Ifomula C18H34O2 (CAS 112-80-1)

Ubloma triglyceride

Isetshenziswa izimonyo okusezingeni eliphezulu ontengo yakhe yayinqunyiwe njengoba amafutha okuthambisa ngempumelelo kakhulu

Found in ubisi fat, ushizi, amafutha omnqumo, amafutha grapeseed, amantongomane, ukwatapheya, amaqanda nenyama

Kwangathi ukubophezeleka iningi Izinzuzo zempilo zamafutha omnqumo!

Amafomu gitar hero izakhiwo nezinye amaprotheni ubisi ukulwa amangqamuzana omdlavuza

Oleoylethanolamide Izinzuzo

Oleoylethanolamide (OEA) muhle ukunciphisa umzimba njengoba iphango nomthetholawulo isekela enempilo amazinga cholesterol abadala.

OEA njengoba iphango avala

Iphango ukucindezelwa iphuzu enkulu olulawulayo amandla (ukudla) eyanele, ukulawula esesuthi kubalulekile ngokulawula isisindo umzimba ube nempilo. Kanjani esesuthi OEA controlyour? Ungase uhlole indlela izenzo ngezansi.

OEA cholesterol

namafutha omnqumo enkulu ukudla, kusiza aphansi "okubi" LDL cholesterol kanye ukwandisa HDL "ezinhle". Kungani? Kufika 85% amafutha omnqumo oleic acid, kanye metabolite main okunempilo oleic acid OEA (Oleoylethanolamide yigama ephelele). Ngakho-ke, akukho kungabaza ukuthi OEA kusiza cholesterol healty.

Ezinye rereearch ebonisa ukuthi oleoylethanolamide kunemiphumela emihle ukukhathazeka, futhi imizila kakhudlwana futhi ubufakazi ezidingekayo ukusekela.

inqubo Oleoylethanolamide Manufacutring

The flow char of Oleoylethanolamide is below:

izinyathelo Genral kuyinto: reactiong → Ukuhlanzwa inqubo → Filtration → Phinda ziyoncibilika Ethanol → hydrogenation → Filtrate Sula Liquid → crystallization → Filtration → Testing → Packing → Umphumela Wokugcina

Mshini wezenzo ka oleoylethanolamide

Ukuyibeka kalula, oleoylethanolamide usebenza njengoba Regulator indlala. OEA uyakwazi ukulawula ukudla ukudla ngokutshela zobuchopho umzimba ugcwele, futhi akukho ukudla kudingeka okwengeziwe. Ungadli kancane nsuku zonke, futhi umzimba wakho kungenzeka yini ukhuluphele ngokuhamba kwesikhathi.

Izenzo anti-ukukhuluphala ka oleoylethanolamide (OEA) is njengoba kukhonjisiwe esithombeni. OEA is kuhlelwe umqondo futhi sahlela ku proximal emathunjini amancane kusukela yokudla-etholakala oleic acid, ezifana amafutha omnqumo. High-amafutha ekudleni singavimbela OEA ukukhiqizwa emathunjini. OEA kunciphisa ukudla ngokwenza kusebenze oxytocin homeostatic futhi histamine ubuchopho bengane busebenze ngendlela kanye hedonic Dopamine izindlela. Kunobufakazi bokuthi OEA ingaphinda attenuate cannabinoid hedonic yokwamukela 1 (CB1R) mkhosi, ukusebenza okuyinto lihlotshaniswa anda ukudla. OEA kunciphisa lipid ezokuthutha zibe adipocytes ukuze wehlise mass amafutha. elucidation Eminye yemiphumela OEA ku ukudla futhi lipid umzimba kuzokusiza ekutholweni izindlela bokuphila ukuthi kungenziwa okubhekiswe izinto zokufutha ukukhuluphala zokwelapha.

OEA isebenza uqalise into okuthiwa PPAR kanyekanye ramps akhuluphale-esivuthayo incipha isitoreji amafutha. Uma udla, amazinga OEA ukwandisa futhi ukudla incipha lapho izinzwa sezinzwa axhunywe ubuchopho bakho ukulitshela ukuthi nigcwele. PPAR-α iqembu yokwamukela ligand-isebenze enuzi abathintekayo ethi isakhi sofuzo of lipid umzimba energyhomeostasis izindlela.

OEA libonisa zonke izici belinganisa wesici satiety:

(1) It kuvimbela encela ngazo ngokuzifaka ngelula kweminyaka isidlo esilandelayo;

(2) zamagama zayo kulawulwa ukutholakala izakhi kanye

(3) Amazinga zayo ibhekane iyehla iyenyuka lomzimba.

Oleoylethanolamide side effects

ukuphepha Oleoylethanolamide kuyinto ekhathazayo kakhulu phakathi ibhekwa brand abafuna ukuba bazame lokhu isithako inoveli kwesisindo yabo amafomula.

Ngemva ukubuyekeza oluphelele zonke izincwadi etholakalayo kanye nedatha, US Food and Drug Administration (FDA) babengenalo ukukhathazeka mayelana nokuphepha OEA sika. RiduZone ungowokuqala uphawu oleoylethanolamide powder isithako kusukela 2015.

Oleoylethanolamide kuyinto metabolite ka oleic acid, oyingxenye ukudla okunempilo nsuku zonke. Kuphephile uzame OEA amaphilisi, futhi akukho nemiphumela enqabayo abikwe.

imiphumela abikwe.

izilingo womuntu Oleoylethanolamide

Kokunye ukuhlola, amahlanu (n = 50) Izikhonzi womuntu abanesifiso ukuncipha bayalwa ukuba athathe OEA izikhathi 2-3 / ngosuku, imizuzu 15-30 ngaphambi kokudla amasonto 4-12. Izihloko kufakwe nalabo ababengazange esetshenziswa isisindo imikhiqizo ukulahlekelwa ngaphambi, nalabo izigameko ezingezinhle ezavela neminye imikhiqizo kwesisindo, labo ukulahleka kabani isisindo plateaued kwamanye ejenti kwesisindo ezifana phentermine, labo abazama ukwenza izinguquko ekuphileni isitayela (control ingxenye nokuvivinya umzimba njalo ), nalabo ngenkuthalo ziphathwa izimo zezokwelapha kuhlanganise kahle glucose ukubekezelelana, dyslipidemia, umfutho ophezulu wegazi kanye izifo zenhliziyo nemithambo yegazi.

Ocwaningweni yesibili, 4 izifundo ezinesisindo lolusisekelo 229, 242, 375 kanye 193 lbs ngokulandelana, bayalelwe ukuthatha amaphilisi Oleoylethanolamide (owodwa capsule equkethe 200mg 90% OEA). Izihloko wathatha 4 amaphilisi (1 capsule imizuzu 15-30 ngaphambi kokudla futhi yibo okwakufanele bathathe i capsule extra ngaphambi ukudla kwabo elikhulu ngosuku) nsuku zonke izinsuku ezingu-28. Isihloko sokugcina wayeke zabhekana ethangeni band ukubekwa. Izihloko bayalelwe ukwenza akukho izinguquko yokudla nokuvivinya umzimba wabo imikhuba.

Ezenye

Esifundweni sokuqala, izihloko elahlekile okuyisilinganiso sabangu-1-2 lbs / ngeviki. Bekungekho miphumela emibi ngaphandle yesinye isiguli uhlangabezana isicanucanu lezivakashi ukuthi yaxazululwa esikhathini esingaphansi kwesonto. Esifundweni yesibili, 3 aphume 4 izifundo kubika kwesisindo (3, 7, 15 no-0 lbs ngokulandelana). Zonke izifundo 4 labika 10-15% ukwehla ngobukhulu ingxenye, isikhathi eside ngezikhathi inter-ukudla, futhi ayinayo imiphumela eseceleni.

Uma unesithakazelo izincwadi ezengeziwe novivinyo womuntu OEA, sicela uvakashele Downloadable-PDF link.

Oleoylethanolamide Isikali

Kukhona elinganiselwe ulwazi locwaningo ku wamanje OEA zinsiza kubantu, futhi ngenkathi uthathwa njengoba ephephile, kungekho umthamo Kunconywa. Nokho, kukhona ezinye Izithako emakethe, futhi ungahle uthole ezinye wenzele inkomba yakho.

I nokushintsha kokudla nokufakwa ngelilanga RiduZone (uphawu OEA / Oleoylethanolamide 90%) is 200mg (1capsule nge OEA kuphela kuwo). Uma ezihlangene kanye nezinye izithako kwesisindo, le nokushintsha kokudla nokufakwa nsuku ibonakala kancane, uthi 100mg noma 150mg. Somesupplements

Kunconywa ukuthatha oleoylethanolamide Izithako imizuzu engu-30 ngaphambi kokudla kwasekuseni kanye dinner, uyozizwa egcwele ngezikhathi zokudla futhi ngenxa yalokho cishe ziyodla kancane.

izincwadi Ucwaningo oleoylethanolamide

Oleoylethanolamide: umdlali omusha olawula amandla umzimba. Indima e ukudla

Oleoylethanolamide kwandisa uwukubonakaliswa PPAR-Α futhi kunciphisa isifiso esisindo kubantu okhuluphele: A ocwaningweni lwezempilo

Brain molecule futhi Iphango: The Case of Oleoylethanolamide

Oleylethanolamide ulawula yokudla nomzimba isisindo ngokusebenzisa kusebenze yokwamukela yenuzi PPAR-a

Ukwenza kusebenze TRPV1 yi satiety Factor Oleoylethanolamide

Regulation ukudla by oleoylethanolamide

Mshini oleoylethanolamide ku okunamafutha acid abatholako e emathunjini amancane emva ukudla nomzimba isisindo ukunciphisa

Oleoylethanolamide: Indima lipid bioactive amidein modulating ukudla ukuziphatha

Oleoylethanolamide: A sizana amafutha ekulweni ukukhuluphala

Oleoylethanolamide: A Novel Abazama Alternative kwemithi ukuze Cannabinoid abamelene ngokuba Ukulawula Iphango