PRL-8-53, le nootropic entsha, eyaziwa ngegama lalo chemical Methyl 3- [2- [Gcoba i-Benzyl (methyl) amino] ETHYL] benzoate ibhekwa zokwenziwa nootropic. Lwakhiwe ngawo-1970 nguDkt Nikolaus Hansl at Creighton University e Nebraska. Kuye kwadingeka abanye izifundo womuntu eyabonisa izimpendulo ezinhle e umsebenzi engqondweni yethu. Olunye ucwaningo lwabonisa ukuthi enkompolo bangasiza ukubuyisa izinkumbulo elahlekile (hypermnesia).
Igama lomkhiqizo: PRL-8-53
Elinye igama: Methyl 3- (2- (benzylmethylamino) ETHYL) hydrochloride benzoate
3- (2-benzylmethylaminoethyl) benzoic acid methyl ester hydrochloride
3- (2- (Methyl (phenylmethyl) amino) ETHYL) benzoic acid methyl ester hydrochloride
Inombolo CAS: 51352-87-5
Yokuncwaninga izinsimbi kanye namakhemikhali: 98%
Ukubukeka: powder White
Kanjani PRL-8-53 Umsebenzi?
PRL-8-53 lisuselwa inhlanganisela benzoic acid phenylmethylamine. Isakhiwo amakhemikhali kwakhiwa kusukela inhlanganisela miphumela ezimbili compounds e ekhuthaza ezingaba uxhumana receptor cholinergic, kuhileleke nezinye izinkinga okuyinto e modulating inkumbulo nokufunda izinqubo ngaphakathi ebuchosheni. PRL-8-53 Kuyaziwa nokuthi potentiate (ukwandisa umphumela) Dopamine futhi kancane kuthiye serotonin receptor. UDkt Nikolaus Hansl wayekholelwa ukuthi le phrofayela umphumela kungenzeka ziholele shift of ibhalansi CNS neurotransmitter izinhlelo futhi kuholele ngcono ukusebenza bokusungula.
Sekube kuphela eyodwa ekuhloleni kwabantu emtholampilo preformed ukuba ahlole imiphumela yetinhlobo izidakamizwa futhi yabonisa ngcono inkumbulo ngamazwi, ezibukwayo ukubuyisa isikhathi nokulawula motor, ikakhulukazi labo abangaphezu kweminyaka engu-Abantu abadala 30. avame ukuba kuncike ngaphezulu yememori kanye nokwehla engqondweni yethu, ngakho-ke, inkumbulo futhi ngokomqondo ngcono Izithako bavame ukusebenza kangcono kuwo.
RPL-8-53 Imisebenzi:
Thuthukisa intelligence engqondo
Khuphula inkumbulo namakhono elincike
Thuthukisa amandla ubuchopho ukuxazulula izinkinga awuvikele iyiphi ikhemikhali noma ukulimala ngokomzimba
Thuthukisa ugqozi ezingeni
Ngcono ukulawula cortical / subcortical ubuchopho indlela
Thuthukisa Umbono sezinzwa
Isikali futhi side effects
Ulwazi lobunikazi etholakalayo PRL 8-53 kusikisela uhla 0.01-4mg / kg bodyweight. Nokho, njengoba okungukuthi uhla enkulu kakhulu, ububanzi okahle 0.05-1.2 mg / kg. Lokhu uhumusha 3.4mg-81.6mg umuntu 150 iphawundi futhi 4.55mg-109mg umuntu 200 iphawundi. Esikhathini Isivivinyo womuntu, ayinayo imiphumela eseceleni zalotshwa; Nokho, encishisiwe motor umsebenzi sifundzile amagundane kanye amagundane benikezwe ngemithamo enkulu PRL 8-53
