Lebitso la Sehlahisoa:RU58841
Lebitso le Leng:4- [3- (4-Hydroxybutyl) -4,4-dimethyl-2,Nomoro ea CAS:154992-24-2
Litlhaloso: 99.0%
'Mala: Phofo e tšoeu e nang le monko le tatso e ikhethang
Boemo ba GMO:GMO Mahala
Ho paka: ka meqomo ea fiber ea 25kgs
Polokelo: Boloka setshelo se sa buloa sebakeng se phodileng, se omileng, Qoba hole le leseli le matla
Shelf Life: Likhoeli tse 24 ho tloha ka letsatsi la tlhahiso
RU58841: Li-Topical Anti-Androgen bakeng sa Lipatlisiso tsa tahlehelo ea Moriri
Non-Steroidal DHT Blocker e nang le Action Localized
Kakaretso ea Sehlahisoa
RU58841 (CAS:154992-24-2), eo hape e tsejoang e le PSK-3841 kapa HMR-3841, ke motsoako o seng oa steroidal oa anti-androgen o qalileng ho etsoa lilemong tsa bo-1990 ke bo-rasaense ba Mafora. Joalo ka mohanyetsi oa li-androgen receptor oa tlholisano, e tlama ho li-receptor tsa follicle ea moriri, e thibela dihydrotestosterone (DHT) ho baka alopecia ea androgenetic (ho lahleheloa ke moriri oa mohlala) ntle le ho fetola maemo a lihomone tsa systemic.
Likarolo tsa Bohlokoa:
- Mechanism: E qothisana lehlokoa le DHT ho li-scalp receptors, ho thibela follicle miniaturization.
- Ketso ea Sebaka: E sebetsa ka holimo ntle le ho fokotsa serum DHT kapa testosterone.
- Katleho: Liteko tsa meriana ho li-primates li bontšitse 103% ea ho hōla ha moriri khahlanong le 88% ka finasteride.
- Bohloeki: ≥99% phofo e tšoeu, e qhibilihang ka har'a lijari tsa ethanol/propylene glycol.
Semelo sa Saense
- Liteko tsa Clinical
- Liteko tsa Phase II tsa Prostrakan (2005) li bontšitse RU58841's ho lekana / bophahamo ho feta finasteride likhoeling tsa 6.
- Li-stumptail macaques, 5% RU58841 tharollo e ile ea feta finasteride ea molomo, e se nang mokhoa oa ho fokotsa DHT.
- Liteko tsa batho li ile tsa khaotsoa ka lebaka la mabaka a sa hlakang (chelete, polokeho, kapa litaba tsa litokelo tsa molao).
- Boemo ba Polokeho
- Litla-morao tse tlalehiloeng: Ho teneha ha lehae, erythema, le litlamorao tse sa tloaelehang tsa sistimi (mohlala, liphetoho tsa libido).
- Tlhokomeliso: Ha e amoheloe ke FDA; lintlha tse fokolang tsa nako e telele tsa polokeho ea batho tse fumanehang .
Litaelo tsa Tšebeliso
Boitokisetso:
- Kopanya 30-100mg RU58841 phofo le 70% ethanol + 30% propylene glycol (mohlala, 0.7ml ethanol + 0.3ml PG ka tharollo ea 1ml) .
Kopo:
- Hloekisa le ho omisa letlalo la hlooho ka botlalo.
- Tšela mokelikeli oa 1ml letsatsi le letsatsi (haholo-holo bosiu) libakeng tse amehileng.
- Qoba ho sebelisoa ka nako e le 'ngoe le lihlahisoa tse nang le oli ho matlafatsa ho monya.
Polokelo:
- Boloka phofo ho -20 ° C; tharollo e lokiselitsoeng e tsitsitse matsatsi a 30 mocheso oa kamore .
Melemo Ho Feta Mekhoa e Meng
| Sebopeho | RU58841 | Finasteride / Minoxidil |
|---|---|---|
| Sebaka sa Ts'ebetso | Sebaka sa lehae (se hlooho feela) | Phokotso ea tsamaiso ea DHT |
| Tšusumetso ea Hormonal | Ha ho serum DHT/T phetoho | E fokotsa DHT ka 70% |
| Tumello ea FDA | Motsoako oa lipatlisiso | OTC e amohetsoeng ke FDA |
| Tekano ho Tšoaneleha | E sebetsa ho banna le basali | Haholo-holo bakeng sa banna |
Theko & Compliance
- Boemo ba Molao: E khethiloe e le k'hemik'hale ea lipatlisiso; eseng bakeng sa tšebeliso ea batho/phoofolo .
- Bafani: E fumaneha ka barekisi ba khethehileng (mohlala, Anageninc, Lyphar Biotech) ka thomello ea libaka.
- Boitlhotlhollo: Ikopanye le litsebi tsa tlhokomelo ea bophelo pele u li sebelisa. Ho latela melao ea lehae ke tlamo .
Mantsoe a sehlooho
- "DHT blocker ea sehlooho bakeng sa tahlehelo ea moriri"
- "RU58841 vs liphetho tsa finasteride"
- "Non-hormonal anti-androgen solution"
- "Motsoako oa lipatlisiso oa PSK-3841"
- Mokhoa oa ho kopanya RU58841 bakeng sa kholo ea moriri
