Trigonelline HClke alkaloid ea tlhaho e nkiloeng peong ea fenugreek, linaoa tsa kofi, le litlama tsa meriana, e tsebahalang ka karolo ea eona e habeli molemong oa bophelo bo botle ba metabolism le methapo. Joalo ka mofuta oa methylated oa nicotinic acid, e netefalitsoe ka mahlale ho fetola litsela tsa lipontšo tsa cellular tse amanang le tekanyo ea tsoekere ea mali, neuroprotection, le bophelo bo bolelele. Phofo ena e phahameng ea bohloeki e sebelisoa haholo ho li-supplement tsa lijo, li-nootropic formulations, le mekhoa e mecha ea lijo.
TrigonelineHCl Powder: Selelekela se tsitsitseng sa NAD+ bakeng sa Mosebetsi o Ntlafetseng oa mesifa le bophelo bo bolelele.
(CAS:6138-41-6| Foromo ea molek'hule: C7H7NO2·HCl)
Kakaretso ea Sehlahisoa
Trigonelline HCl Powder, alkaloid ea tlhaho e tsoang limela tse kang peo ea fenugreek (Trigonella foenum-graecum) le linaoa tsa kofi, ke selelekela sa NAD + se tsitsitseng haholo. E bapala karolo ea bohlokoa ho loants'eng ho theoha ha mesifa e amanang le lilemo (sarcopenia), ho ntlafatsa ts'ebetso ea mitochondrial, le ho khothaletsa bophelo bo bolelele ba lisele ka NAD+ biosynthesis.
Melemo ea Bohlokoa
- NAD+ Boosting & Anti-botsofali
Trigonelline e phahamisa maemo a intracellular NAD+ ka nepo, e leng coenzyme e hlokahalang bakeng sa karabelo ea metabolic e fetang 500, ho kenyelletsa tlhahiso ea matla ea mitochondrial, tokiso ea DNA, le phokotso ea ho ruruha. Ho tsitsa ha eona ho feta li-precursor tse ling tsa NAD+ joalo ka NMN le NR, e etsa hore e be e loketseng bakeng sa tlatsetso ea nako e telele. - Bophelo bo Botle ba Mesifa le Thibelo ea Sarcopenia
Lithuto tsa tleliniki li amahanya maemo a phahameng a serum trigonelline ho ntlafatsa boima ba mesifa, matla a ho tšoara, le lebelo la ho tsamaea - matšoao a bohlokoa a bophelo bo botle ba mesifa. E hanyetsana le sarcopenia ka ho matlafatsa tšebetso ea lisele tsa sathelaete le ho fokotsa khatello ea oxidative mesifa ea botsofali. - Tšehetso ea Metabolic & Neuroprotective
Trigonelline e bonts'a thepa ea hypoglycemic, hypolipidemic, le neuroprotective. E thusa ho laola tsoekere ea mali, e fokotsa tšenyo ea oxidative, 'me e ka fokotsa likotsi tsa neurodegenerative. - Antioxidant & Anti-Inflammatory Effects
Ka ho fokotsa li-radicals tsa mahala le ho fetola litsela tsa ho ruruha, trigonelline e sireletsa khahlanong le tšenyo ea lisele le ho tšehetsa matla ka kakaretso.
Mokhoa oa Ts'ebetso
- NAD+ Synthesis: Joalo ka vithamine B3 metabolite, trigonelline e fetoha NAD+ ka tsela ea salvage, e khutlisetsa matla a cellular le botsitso.
- Ntlafatso ea Mitochondrial: E ntlafatsa katleho ea mitochondrial ka ho laola liprotheine tsa phefumoloho ea oxidative le ho fokotsa khatello ea oxidative.
- Tsosoloso ea Mesifa: E khothalletsa protheine synthesis le satellite cell activation, ea bohlokoa bakeng sa ho boloka mesifa e boima.
Netefatso ea Mahlale
- Phuputso ea 2024 e bonts'itse hore tlatsetso ea trigonelline e ekelitse maemo a NAD+ ka 30% meleng ea mesifa, e tsamaellanang le lebelo le ntlafetseng la ho tsamaea le matla a ho tšoara ho batho ba tsofetseng.
- Liteko tsa pele ho likhoto tsa lefu la tsoekere li bonts'itse trigonelline e fokolitse tsoekere ea mali ka 25% le ho ruruha ha liphio, ho totobatsa melemo ea eona ea metabolic.
- Tlhahlobo ea HPLC e tiisa bohloeki bo phahameng (≥98%) le ho qhibiliha metsing, ho netefatsa hore bioavailability e nepahetseng .
Tšebeliso le Tekanyetso
- Mokhoa o khothalletsoang: 250-500 mg ka letsatsi, o qhibilihisoa ka metsing kapa o kopantsoe le smoothies.
- Tšireletseho: Ha e na chefo ho litekanyetso tsa kliniki; e lumellana le litekanyetso tsa GMP. Qoba nakong ea bokhachane kapa haeba alejiki ho limela tsa linaoa.
Netefaletso ea boleng
- Nomoro ea CAS: 6138-41-6 | Bohloeki: ≥98% (HPLC-e netefalitsoe)
- Litifikeiti: E entsoe ka tlas'a litataiso tsa ISO, ka tlhahlobo ea motho oa boraro bakeng sa litšepe tse boima le litšila tse nyane.
Ke Hobane'ng ha U Re Khetha?
Joalo ka morekisi ea etelletseng pele oa lisebelisoa tsa bophelo bo bolelele (mohlala, NMN, NAD+ booster), re netefatsa phofo ea trigonelline HCl ea maemo a holimo e nang le likhetho tse ngata tse ikhethileng. Selekane le rona ho ntlafatsa litlolo tsa hau tsa tlatsetso le ho hlokomela 'maraka o ntseng o hola o thibelang botsofali.
Mantsoe a sehlooho
NAD + selelekela, tlatsetso ea ts'ebetso ea mesifa, phofo e thibelang botsofali, Trigonelline HCl CAS 6138-41-6, kalafo ea sarcopenia, tlhahiso ea fenugreek, tšehetso ea mitochondrial
