Naringenin na isakhiwo amathambo a flavanone ezintathu amaqela hydroxy kwi-4, 5, kunye carbons 7. Ifumaneka zombini kwi aglycol ifomu, naringenin, or in its glycosidic ifomu, naringin , leyo kongezwe disaccharide neohesperidose esiqhotyoshelweyo nge glycosidic zoqhakamshelwano kwi carbon 7.Like uninzi flavanones, naringenin na iziko eyodwa chiral kwi carbon 2, oko kukhokelele enantiomeric iintlobo ezimbaxa. Le enantiomers zifumaneka ezahlukeneyo ngawona kuzo imithombo yendalo. Racemization of S (-) - naringenin kuye kwabonakala ukuba zenzeke ngokukhawuleza. Naringenin kuye kwabonakala ukuba zimelane enatiomerization phezu pH 9-11.
Ngokwahlukana uhlahlelo enantiomers sele ekhangelwe nkalwana iminyaka engaphezu kwama-20, ngokuyintloko nge high-yokusebenza chromatography ulwelo kwi zigaba zokubhala chiral polysaccharide-impiriyali. Kukho ubungqina obubonisa stereospecific pharmacokinetics kunye pharmacodynamics profiles, leyo kuye kwandululwa ukuba ingcaciso ezininzi in naringenin ingxelo bioactivity.
Naringenin kunye glycoside yayo iye yafunyanwa ezahlukeneyo imifuno kunye neziqhamo , kubandakanywa grapefruit , bergamot , -orenji ezimuncu , cherry apile , iitumato , ikoko , oregano yamaGrike , zetyeleba amanzi , drynaria ngokunjalo iimbotyi .Ratios of naringenin ukuya naringin liyahluka phakathi imithombo, njengoko kwenza zilinganiso enantiomeric.
Pure Natural Naringenin
CAS #: 480-41-1
[Igama IsiNgesi]: Naringenin
[Specification]: 98%
[iipropati Product]: off-powder emhlophe
[Test indlela]: solibalo
[Ifomula]: C15H12O5
[CAS.NO]: 480-41-1
[ubunzima eziphilayo]: 272,25 g • Mol-1
onyibilikayo Point & Ukunyibilika: mp251 ° C, enyibilikayo ngotywala, iEtere kunye benzene. phantse ezingenakunyibilika ngamanzi.
Igama Product: Naringenin 9 8%
Ingcaciso: 98% ngo solibalo
Igama Product: Naringenin
souurce Botanical: zesitrasi grandis Osbeck (L.)
CAS NO.480-41-1
Inkangeleko: White okanye off ngumgubo ezimhlophe
YeMfuzo Ubume: yeMfuzo Free
Ukupakisha: ngo 25kgs imigqomo ifayibha
Storage: Gcina isikhongozeli bengawatyi apha, kwindawo eyomileyo epholileyo, Gcina kude wokukhanya onamandla
Ubude bethuba Life: iinyanga ezingama-24 ukususela kumhla yemveliso
1. Naringenin uye anticancer ukusebenza, inokubulala iiseli zomhlaza ezahlukeneyo.
2. Naringenin ngandlela yokhuselo kwi focal palsy ischemia reperfusion kumabuzi, yaye uyakwazi zingangqamana kunye ngokudla yayo olusebenzayo radicals simahla. Naringenin kakhulu zasinciphisa isiqulatho amanzi yobuchopho, kunciphise umthamo iqhosha yobuchopho ye ikhweyitha ingqondo kakuhle, bazifinyeza inqanaba Mda kwaphucula umsebenzi olu obuchopho. Le ibonisa Naringenin ayikwazi ngandlela yokhuselo kwi ikhweyitha ebuchotsheni.
3. Naringenin uyakwazi kakhulu ukwehlisa yoxinaniso plasma cholesterol kunye nomxholo cholesterol hepatic.
4. Naringenin iye yabonisa ukuba ukunciphisa hepatitis C imveliso igciwane hepatocytes ezosulelekileyo (iiseli kwesibindi) ku
inkcubeko cell. Oku kubonakala ukuba lesibini ukuya Narigenin ukukwazi zinqanda secretion of lipoprotein loxinano aphantsi gqitha iiseli.
5.Naringenin ngandlela bioactive kwimpilo yabantu njengoko antioidant, scavenger ezamahala ezinkulu, antisepsis, anti-ukudumba, umsebenzi antispasmodic.
isicelo
Disease 1.Alzheimer kaThixo
Naringenin kuqatyeliswa uphando njengonyango enokwenzeka for Disease i-Alzheimer. Naringenin iye yabonisa ukuba ulole nokunciphisa amyloid kunye otau iiproteni isifundo usebenzisa imodeli mouse ye Disease i-Alzheimer.
2.Antibacterial, nokubola, kwaye antiviral
Kukho ubungqina neziphumo antibacterial kwi H. pylori. Naringenin iye yabonisa ukuba ukunciphisa hepatitis C imveliso igciwane hepatocytes ezosulelekileyo (iiseli kwesibindi) kwinkcubeko cell. Oku kubonakala ukuba lesibini ngokwawakhe naringenin ukuba zinqanda secretion of lipoprotein kakhulu-esezantsi ezinoxinano yi iiseli. Imiphumo antiviral of naringenin okwangoku phantsi kophando clinical. Iingxelo neziphumo antiviral kwi zepoliyo HSV-1 HSV-2 kuye kwenziwa, nangona phindana iintsholongwane khange elinganeno.
3. Antioxidant
Naringenin kuye kwabonakala ukuba iipropati antioxidant ebalulekileyo.
Naringenin iye yabonisa ukuba ukunciphisa umonakalo oxidative ukuya DNA in vitro kunye nezifundo zezilwanyana.
|
Ulwazi ngaphezulu TRB |
||
| sokuqinisekisa Regulation | ||
| USFDA, ¸cep, HALAL zaseKosher GMP ISO Iziqinisekiso | ||
| Quality ezinokuthenjwa | ||
| Phantse 20 iminyaka, kumanye amazwe 40 kunye nemimandla, ngaphezulu kwama-2000 iibhetshi eziveliswe TRB ukuba akukho naziphi na iingxaki umgangatho, inkqubo zokuhlanjululwa unique, ukungcola kunye nolawulo ntumbuluko ukuhlangana USP, EP kunye CP | ||
| Quality System Comprehensive | ||
|
|
▲ System Quality Assurance |
√ |
| ▲ ukulawula Document |
√ |
|
| ▲ Ukuqinisekisa System |
√ |
|
| ▲ System Training |
√ |
|
| ▲ Protocol Internal Audit |
√ |
|
| ▲ Suppler Audit System |
√ |
|
| ▲ Equipment Facilities System |
√ |
|
| ▲ Material Control System |
√ |
|
| ▲ Production Control System |
√ |
|
| ▲ Packaging Ukuphawula System |
√ |
|
| ▲ Laboratory Control System |
√ |
|
| ▲ Ukuqinisekisa Ulwenziwo System |
√ |
|
| ▲ Regulatory Affairs System |
√ |
|
| ULawulo Wonke Imithombo neenkqubo | ||
| kulawulwe zonke izinto ekrwada, izincedisi kunye nokupakishwa materials.Preferred ekrwada izixhobo kunye nezincedisi kunye nezinto zokubopha umthengisi kunye US DMF number.Several abathengisi izinto zokwenza imveliso njengoko nesiqinisekiso sonikezelo. | ||
| Amaziko Strong Cooperative ukuxhasa | ||
| Institute of Botany / Institution of eziphilayo / Academy of Science and Technology / University | ||
