S-Adenosyl methionine is a common cosubstrate involved in methyl group transfers, transsulfuration, and aminopropylation. Although these anabolic reactions occur throughout the body, most SAM-e is produced and consumed in the liver. More than 40 methyl transfers from SAM-e are known, to various substrates such as nucleic acids, proteins, lipids and secondary metabolites. It is made from adenosine triphosphate (ATP) and methionine by methionine adenosyltransferase. SAM was first discovered by Giulio Cantoni in 1952.
In bacteria, SAM-e is bound by the SAM riboswitch, which regulates genes involved in methionine or cysteine biosynthesis. In eukaryotic cells, SAM-e serves as a regulator of a variety of processes including DNA, tRNA, and rRNA methylation; immune response; amino acid metabolism; transsulfuration; and more. In plants, SAM-e is crucial to the biosynthesis of ethylene, an important plant hormone and signaling molecule.
Product Name:S-Adenosyl-L-methionine(SAMe)
CAS No:29908-03-0
Molecular Formula: C15H22N6O5S
Molar mass: 398.44 g·mol−1
Specification:98% by HPLC
Appearance:White Powder with characteristic odor and taste
GMO Status:GMO Free
Packing: in 25kgs fiber drums
Storage:Keep container unopened in cool, dry place,Keep away from strong light
Shelf Life:24 months from date of production
Function:
–SAMe is a good nutrition for the liver,can prevent alcohol, drugs and the liver-cell injury;
–SAMe has remarkable preventive effects on chronic active hepatitis, and other factors caused liver injury,heart disease, cancer and so on.
–SAMe has been found to be as effective as pharmaceutical treatments for arthritis and major depression as well.
Application:
–As Food and beverage ingredients.
–As Healthy Products ingredients.
–As Nutrition Supplements ingredients.
–As Pharmaceutical Industry & General Drugs ingredients.
–As a health food and cosmetic ingredients
