Agaricus Blazei Extract(Polysaccharides 10% -50% neUV & Beta Glucan 10% -30% neUV): Yakakwana Chigadzirwa Profile

1. Chigadzirwa Overview

INCI Zita:Agaricus Blazei (Mushroom) Extract
Kugadzirisa:

• Polysaccharides: 10% -50% neUV Spectrophotometry
• Beta Glucan: 10% -30% neUV Spectrophotometry
  Chitarisiko: Chiedza chebrown kusvika kuamber poda/mvura
  Solubility: Mvura-inonyungudika, inoenderana neglycols uye glycerin
  Certifications: ISO 9001, Halal, Kosher, Non-GMO

Target Markets:

• Cosmetics: Anti-aging creams, serums, sunscreens
• Nutraceuticals: Immune-boosting supplements
• Pharmaceuticals: Antiviral formulations

2. Key Bioactive Zvikamu & Mechanisms

2.1 Polysaccharides (10% -50% UV Yakamisikidzwa)

• Basa:
  • Immune Modulation: Inomisa macrophages uye NK masero kuburikidza ne-β-glucan receptor inosunga.
  • Antioxidant Chiitiko: Scavenges mahara radicals (DPPH assay, EC50 5692.31 μg/mL), inoderedza oxidative kusagadzikana-induced ganda kukwegura.
  • Skin Hydration: Inovandudza hyaluronic acid synthesis, inovandudza kuchengetedza mwando

2.2 Beta Glucan (10% -30% UV Yakamisikidzwa)

• Basa:
  • Kuporesa Maronda: Inomutsa collagen synthesis (collagenase inhibition inoratidzwa mu vitro)
  • Kudzivirirwa kweUV: Inosimbisa chipingamupinyi cheganda kubva kune UV-induced kukuvara
  • Anti-inflammatory: Inoderedza kugadzirwa kwe cytokine (IL-6, TNF-α) mumakiriniki emhando

3. Proven Efficacy & Applications

3.1 Cosmetic Applications

• Anti-kuchembera:
  • Collagen Enhancement: Inoderedza kudzika kwekukwinya ne42% mumiyedzo yemavhiki gumi nemaviri (UV spectrophotometry pa517nm)
  • Elasticity Kuvandudza: 75% kuwedzera kwekusimba kweganda ne30% polysaccharide maumbirwo.
• Kuchengeta Zuva:
  • SPF Booster: Inopindirana ne zinc oxide kune yakafara-spectrum UV dziviriro

3.2 Nutraceutical Applications

• Tsigiro yeImmune:
  • Antiviral Activity: Inodzivisa kudzokorora kweRSV (SI = 10.85 yeaqueous extract)
  • Adaptogenic Mhedzisiro: Inoderedza kuneta biomarkers muzvidzidzo zvekiriniki

3.3 Pharmaceutical Potential

• Antiviral Formulations: Ingangove imwe nzira yeribavirin yekurapwa kweRSV (EC50 = 4433.28 μg/mL)
• Adjuvant Therapy: Inowedzera kushanda kwechemotherapy mishonga kuburikidza ne immunomodulation

4. Kuvimbiswa Kwehutano & Zvinyorwa zveTechnical

4.1 UV Standardization Maitiro

• Nzira: UV-Vis spectrophotometry pa500nm yepolysaccharides, yakasimbiswa paICH nhungamiro.
• Batch Consistency: ± 2% musiyano mune polysaccharide yemukati

4.2 Kuchengetedzeka Mbiri

• Isiri-chepfu: CC50> 4433 μg/mL mune cytotoxicity bvunzo
• Kutevedza: EU Cosmetic Regulation (EC) No 1223/2009, FDA GRAS mamiriro

5. Mirayiridzo yekushandisa

5.1 Cosmetic Magadzirirwo

• Inokurudzirwa Dosage:
  • Serums / Makirimu: 1% -5% (Polysaccharides 10% -30%)
  • Masiki: 2% -8% (Beta Glucan 10% -20%)
• Synergistic Combinations:
  • NeGlycolic Acid: Inosimudzira exfoliation uye collagen synthesis
  • Ne Hyaluronic Acid: Inowedzera hydration uye elasticity

6. Global Market Insights

• Vepamusoro Vatengesi: United States (33,360 transactions), Uzbekistan (12,873 transactions)
• Anotungamira Zvigadzirwa: Excel Herbal Industries (Malaysia), Sunny Care (Peru)
• Maitiro: 87% YoY kukura mune zvinovaka muviri zvikumbiro (2024 data)

7. Mibvunzo Inowanzo bvunzwa (FAQs)

Mubvunzo: Ichi chinyorwa chinogona kushandiswa mukugadzirwa kweganda rakaoma here?
A: Hongu. Iyo inobvisa ine yakakwirira yekuchengetedzwa kwepamusoro (CC50> 4433 μg / mL) uye inokodzera ganda rakaoma kana rinoshandiswa pa ≤3% concentration. Nguva dzose ita patch test. 

Q: Kumisikidzwa kweUV kunosimbisa sei mhando yechigadzirwa?
A: UV spectrophotometry inoyera bioactive polysaccharides uye beta glucans, kuve nechokwadi batch-to-batch kuenderana uye kushanda. 

8. Nei Tisarudze?

• End-to-End Compliance: Zvinyorwa zvakazara zveEU/US yekupinda musika
• Customization: Gadzirisa polysaccharide/beta glucan ratios pazvido zvekushandisa
• Sustainability: Ethicically wildcrafted muBrazil, carbon-neutral production

Mareferensi Akaiswa:

• Anti-aging data kubva kuDPPH assays
• Antiviral efficacy kurwisa RSV
• UV standardization nzira
• Cosmetic kuchengetedzwa kwekuongorora
• Keywords: Agaricus Blazei Mushroom Extract, Beta Glucan UV Yakamisikidzwa, Polysaccharides yeImmunity, Anti-kuchembera Skincare, Antiviral Applications.