I-Agaricus Blazei Extract(Polysaccharides 10% -50% by UV & Beta Glucan 10%-30% by UV): Iphrofayili Yomkhiqizo Ephelele

1. Uhlolojikelele lomkhiqizo

INCI Igama:I-Agaricus Blazei (Ikhowe) Ingcaphuno
Ukumisa:

• Ama-Polysaccharides: 10% -50% nge-UV Spectrophotometry
• I-Beta Glucan: 10% -30% nge-UV Spectrophotometry
  Ukubukeka: Okunsundu ngokukhanyayo ukuya kumpushana we-amber/uketshezi
  I-Solubility: Amanzi ancibilikayo, ahambisana nama-glycols ne-glycerin
  Izitifiketi: ISO 9001, Halal, Kosher, Non-GMO

Izimakethe eziqondiwe:

• Izimonyo: Okhilimu bokuguga, amaserum, okokuvikela ilanga
• I-Nutraceuticals: Izithako ezikhuthaza amasosha omzimba
• Imithi: Ukwakhiwa kwe-Antiviral

2. Izingxenye Ezibalulekile Ze-Bioactive & Izindlela

2.1 I-Polysaccharides (10% -50% UV Standardized)

• Umsebenzi:
  • Ukuguqulwa Kwamasosha omzimba: Yenza kusebenze ama-macrophage namaseli e-NK ngokubopha i-β-glucan receptor
  • Umsebenzi we-Antioxidant: Scavenges free radicals (DPPH assay, EC50 5692.31 μg/mL) , yehlisa ukuguga kwesikhumba okubangwa yi-oxidative
  • I-Skin Hydration: Ithuthukisa i-hyaluronic acid synthesis, ithuthukisa ukugcinwa komswakama

2.2 I-Beta Glucan (10% -30% UV Standardized)

• Umsebenzi:
  • Ukupholiswa Kwezilonda: Kuvuselela i-collagen synthesis (i-collagenase inhibition eboniswe ku-vitro)
  • Ukuvikelwa kwe-UV: Kuqinisa umgoqo wesikhumba emonakalweni owenziwe yi-UV
  • I-Anti-inflammatory: Yehlisa ukukhiqizwa kwe-cytokine (IL-6, TNF-α) kumamodeli omtholampilo

3. Ukusebenza Okuqinisekisiwe Nezicelo

3.1 Izicelo Zezimonyo

• I-Anti-Aging:
  • Ukuthuthukisa i-Collagen: Yehlisa ukujula kokushwabana ngo-42% ezivivinyweni zamaviki angu-12 (i-UV spectrophotometry ku-517nm)
  • Ukuthuthukiswa kwe-Elasticity: ukwanda ngo-75% kokuqina kwesikhumba ngama-30% e-polysaccharide formulations
• Ukunakekela Ilanga:
  • I-SPF Booster: Isebenzisana ne-zinc oxide ukuze kuvikelwe i-UV ebanzi

3.2 Izicelo Zokudla

• Ukwesekwa Kwamasosha omzimba:
  • Umsebenzi Wokuvimbela Amagciwane: Ivimbela ukuphindaphinda kwe-RSV (SI = 10.85 ngokukhishwa okumanzi)
  • Umphumela we-Adaptogenic: Yehlisa ama-biomarker wokukhathala ezifundweni zomtholampilo

3.3 Amandla Ezemithi

• Amafomu Alwa Namagciwane: Okunye okungase kube khona i-ribavirin yokwelashwa kwe-RSV (EC50 = 4433.28 μg/mL)
• I-Adjuvant Therapy: Ithuthukisa ukusebenza kwezidakamizwa ze-chemotherapy nge-immunomodulation

4. Ukuqinisekiswa Kwekhwalithi Nemininingwane Yezobuchwepheshe

4.1 Inqubo yokumiswa kwe-UV

• Indlela: I-spectrophotometry ye-UV-Vis ku-500nm yama-polysaccharides, aqinisekiswa ngokwemihlahlandlela ye-ICH
• Ukungaguquguquki kweqoqo: ±2% ukwehluka kokuqukethwe kwe-polysaccharide

4.2 Iphrofayili yezokuphepha

• Okungewona ubuthi: CC50 > 4433 μg/mL ekuhlolweni kwe-cytotoxicity
• Ukuthobela: I-EU Cosmetic Regulation (EC) No 1223/2009, isimo se-FDA GRAS

5. Iziqondiso Zokusetshenziswa

5.1 Amafomula Wezimonyo

• Umthamo onconyiwe:
  • AmaSerum/Amakhilimu: 1%-5% (Polysaccharides 10%-30%)
  • Imaski: 2% -8% (Beta Glucan 10% -20%)
• Inhlanganisela ye-Synergistic:
  • Nge-Glycolic Acid: Ithuthukisa i-exfoliation kanye nokuhlanganiswa kwe-collagen
  • Nge-Hyaluronic Acid: Ithuthukisa ukugeleza kwamanzi nokunwebeka

6. I-Global Market Insights

• Abathekelisi Abaphezulu: I-United States (33,360 transactions), Uzbekistan (12,873 transactions)
• Imikhiqizo ehamba phambili: I-Excel Herbal Industries (Malaysia), Sunny Care (Peru)
• Amathrendi: 87% Yokukhula kwe-YoY kuzinhlelo zokusebenza ze-nutraceutical (idatha ka-2024)

7. Imibuzo Evame Ukubuzwa (FAQs)

Q: Ingabe lokhu kukhishwe kungasetshenziswa ekwakhiweni kwesikhumba esibucayi?
A: Yebo. I-extract inephrofayili yokuphepha ephezulu (CC50> 4433 μg/mL) futhi ifanele isikhumba esibucayi uma isetshenziswa ekugxiliseni okungu-≤3%. Njalo yenza ukuhlolwa kwesichibi. 

Q: Ukumisa kwe-UV kuqinisekisa kanjani ikhwalithi yomkhiqizo?
A: I-spectrophotometry ye-UV ilinganisa ama-polysaccharides e-bioactive nama-beta glucan, iqinisekisa ukufana kwe-batch-to-batch nokusebenza ngempumelelo. 

8. Kungani Usikhethe?

• Ukuthobela Ukuphela Kuya Ekupheleni: Amadokhumenti aphelele okungena emakethe ye-EU/US
• Ukwenza ngokwezifiso: Lungisa izilinganiso ze-polysaccharide/beta glucan ngezidingo zohlelo lokusebenza ngalunye
• Ukusimama: Kuklanywe ngendlela efanele e-Brazil, ukukhiqizwa kwe-carbon-neutral

Izithenjwa zishumekiwe:

• Idatha yokunqanda ukuguga evela ekuhlolweni kwe-DPPH
• Ukusebenza kwe-Antiviral ngokumelene ne-RSV
• Izindlela zokumiswa kwe-UV
• Ukuhlolwa kokuphepha kwezimonyo
• Amagama angukhiye: I-Agaricus Blazei Mushroom Extract, i-Beta Glucan UV Standardized, i-Polysaccharides for Immunity, I-Anti-Aging Skincare, Izicelo Zokuvimbela Amagciwane