CDP-CHOLINE

Short Description:

Name:CDP-CHOLINE,CITICOLINE
Chemical name:cytidine5’-diphosphatecholine
Molecular Formula:C14H26N4O11P2
CAS:987-78-0
Einecs NO:213-580-7
Formula Weight:488.33
Apearance: Off white powder.
Purity:98%
Citicoline (INN), also known as cytidine diphosphate-choline (CDP-Choline) or cytidine 5′-diphosphocholine is nootropic. It is an intermediate in the generation of phosphatidylcholine from choline.
Studies suggest that CDP-choline supplements increase dopamine receptor densities, and suggest that CDP-choline supplementation helps prevent memory impairment resulting from poor environmental conditions. Preliminary research has found that citicoline supplements help improve focus and mental energy and may possibly be useful in the treatment of attention deficit disorder.
Citicoline has also been shown to elevate ACTH independently from CRH levels and to amplify the release of other HPA axis hormones such as LH, FSH, GH and TSH in response to hypothalamic releasing factors. These effects on HPA hormone levels may be beneficial for some individuals but may have undesirable effects in those with medical conditions featuring ACTH or cortisol hypersecretion including PCOS, type II diabetes and major depressive disorder.


  • FOB Price: US $0.5 - 9,999 / KG
  • Min.Order Quantity: 1 KG
  • Supply Ability: 10000 KG/per Month
  • Port: SHANGHAI/BEIJING
  • Payment Terms: L/C,D/A,D/P,T/T
  • Product Detail

    Product Tags

    Name:CDP-CHOLINE,CITICOLINE
    Chemical name:cytidine5’-diphosphatecholine
    Molecular Formula:C14H26N4O11P2
    CAS:987-78-0
    Einecs NO:213-580-7
    Formula Weight:488.33
    Apearance: Off white powder.
    Purity:98%
    Citicoline (INN), also known as cytidine diphosphate-choline (CDP-Choline) or cytidine 5′-diphosphocholine is nootropic. It is an intermediate in the generation of phosphatidylcholine from choline.
    Studies suggest that CDP-choline supplements increase dopamine receptor densities, and suggest that CDP-choline supplementation helps prevent memory impairment resulting from poor environmental conditions. Preliminary research has found that citicoline supplements help improve focus and mental energy and may possibly be useful in the treatment of attention deficit disorder.
    Citicoline has also been shown to elevate ACTH independently from CRH levels and to amplify the release of other HPA axis hormones such as LH, FSH, GH and TSH in response to hypothalamic releasing factors. These effects on HPA hormone levels may be beneficial for some individuals but may have undesirable effects in those with medical conditions featuring ACTH or cortisol hypersecretion including PCOS, type II diabetes and major depressive disorder.

    Certificate of Analysis

    Product Information
    Product Name: Citicoline(CDP-Choline)
    CAS No.: 987-78-0
    Molecular formula: C14H26N4O11P2
    Batch No. TRB-CDP-20190620
    MFG Date: June 20,2019

     

    Item

    Specification Test Results
    Active Ingredeints
    Assay(%.On Dried Base) 98.0%~102.0% by HPLC 100.30%
    Physical Control
    Appearance Fine crystalline Powder Complies
    Color White to Off White

    Complies

    Identification NMR

    Complies

    PH 2.5~3.5

    3.3

    Loss on Drying 1.0% Max 0.041%
    Water                                1.0% Max 0.052%
    5’-CMP                              NMT1.0% 0.10%
    Chemical Control
    Heavy metals NMT10PPM

    Complies

    Arsenic(As2O3) NMT1PPM

    Complies

    Sulfate(SO4) NMT 0.020%

    Complies

    Iron(Fe) NMT10PPM

    Complies

    Chloride(Cl) NMT 0.020%

    Complies

    Solvent Residual Meeting EU/USP Standard

    Complies

    Microbiological Control
    Total Plate Count 10,00cfu/g Max

    Complies

    Yeast & Mold 100cfu/g Max

    Complies

    E.Coli Negative/10g

    Complies

    Salmonella sp. Negative/25g

    Complies

    Staph Aureus Negative/10g

    Complies

    Pseudomonas aeruginosa Negative/25g

    Complies

    Packing and Storage
    Packing Pack in paper-drums. 25Kg/Drum 1Kg per plastic bag
    Storage Store in a well-closed container away from moisture and direct sunlight.
    Shelf Life 2 years if sealed and stored properly.

    More information of TRB

    Regulation certification
    U.S.FDA,CEP,KOSHER HALAL GMP ISO Certificates
    Reliable Quality
    Nearly 20 years,export 40 countries and regions,more than 2000 batches produced by TRB have no any quality problems,unique purification process,impurity and purity control meet USP,EP and CP
    Comprehensive Quality System

     

    ▲Quality Assurance System

    ▲ Document control

    ▲ Validation System

    ▲ Training System

    ▲ Internal Audit Protocol

    ▲ Suppler Audit System

    ▲ Equipment Facilities System

    ▲ Material Control System

    ▲ Production Control System

    ▲ Packaging Labeling System

    ▲ Laboratory Control System

    ▲ Verification Validation System

    ▲ Regulatory Affairs System

    Control Whole Sources and Processes
    Strictly controlled all raw material,accessories and packaging materials.Preferred raw materials and accessories and packaging materials supplier with U.S. DMF number.Several raw material suppliers as supply assurance.
    Strong Cooperative Institutions to support
    Institute of botany/Institution of microbiology/Academy of Science and Technology/University

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