ʻO ka Covid-19, a i ʻole kapa ʻia ʻo 2019-nCoV a i ʻole SARS-CoV-2 virus, no ka ʻohana o Coronavirus. ʻOiai ʻo SARS-CoV-2 no ka β genus Coronavirus pili loa ia i ka MERS-CoV a me ka SARS-CoV - a ua hōʻike pū ʻia kekahi e hōʻike ana i nā ʻōuli ʻino o ka pulumonia i nā maʻi kūpuna i hala. ʻO ke ʻano kūpuna o ka makahiki 2019-nCoV i hōʻike ʻia a paʻi ʻia.
ʻO ka mea hou o kēia kānana o ka maʻi he nui ia o ka maopopo ʻole e pili ana i kāna ʻano, no laila, ua hikiwawe loa e hoʻoholo inā hiki i nā mea kanu lāʻau a i ʻole nā mea hoʻohui ke hāʻawi i ka hui kaiāulu e like me nā mea prophylactic a i ʻole nā mea kūpono i nā lāʻau anti-coronavirus e kūʻē iā Covid -19. Eia nō naʻe, ma muli o ke ʻano like o Covid-19 me nā virus ʻo SARS-CoV a me MERS-CoV i hōʻike mua ʻia, ua noiʻi mua ʻia e pili ana i nā mea kanu lāʻau, i hōʻoia ʻia e hana i nā hopena anti-coronavirus, he alakaʻi nui paha ia e loaʻa ai ka anti-coronavirus nā mea kanu lāʻau, i hiki ke hana kūʻē i ka maʻi maʻi SARS-CoV-2.
Ma hope o ka haki ʻana o SARS-CoV, i hōʻike mua ʻia i ka makahiki 2003 [iii], ua hoʻāʻo ikaika ka poʻe ʻepekema e hoʻohana i nā hui antiviral e kūʻē iā SARS-CoV. Ua alakaʻi kēia i kahi hui o ka poʻe loea ma Kina e nānā ma mua o 200 o nā mea kanu lāʻau lāʻau Kina no nā hana antiviral e kūʻē i kēia ʻino coronavirus.
Ma waena o kēia mau mea, ua hōʻike ʻia he ʻehā mau extract i ka hopena o ka hopena i ka hopena ikaika e kūʻē iā SARS-CoV - Lycoris radiata (Red Spider Lily), Pyrrosia lingua (a fern), Artemisia annua (Sweet wormwood) a me Lindera i hōʻuluʻulu ʻia (kahi lālā ulu ulu mau o ka ʻohana laurel ). ʻO nā hopena antiviral o kēia mau mea kaukaʻi hilinaʻi a kau ʻia mai nā hoʻohaʻahaʻa haʻahaʻa o ka extract i ke kiʻekiʻe, ʻokoʻa no kēlā me kēia lāʻau herbal. Ua hōʻike ʻo Lycoris radiata i ka hana anti-viral ikaika loa e kūʻē i ka maʻi virus. [Iv]
Ua kūlike kēia hopena me nā hui noiʻi ʻelua ʻē aʻe, i hōʻike ʻia i kahi mea paʻa i loko o nā aʻa ʻo Licorice, ʻo Glycyrrhizin, i hōʻoia ʻia e loaʻa kahi hana anti-SARS-CoV ma o ka pāpā ʻana i kāna hana hou. [V] [vi] I kekahi ke aʻo ʻana, hōʻike pū ʻo Glycyrrhizin i ka hana antiviral ke hoʻāʻo ʻia no kāna hopena vitro antiviral ma 10 mau ʻano kaʻawale o ka SARS coronavirus. ʻO Baicalin - kahi mea kanu o ka mea kanu Scuttelaria baicalensis (Skullcap) - ua hoʻāʻo ʻia hoʻi i kēia noi ʻana ma lalo o nā kūlana like a ua hōʻike pū ʻia ka hana antiviral e kūʻē i ka coronavirus SARS. [Vii] Ua hōʻike ʻia ʻo Baicalin e kāohi i ka hana hou ʻana o ka maʻi HIV. -1 virus i vitro i loko o nā haʻawina i hala. [Viii] [ix] Eia nō naʻe e hoʻomaopopo ʻia ʻaʻole i pili nā ʻike i loko o ka vitro me ka vivo clinical efficacy. ʻO kēia no ka mea ʻaʻole i hoʻokō ʻia ka hopena waha o kēia mau ʻākena i loko o ke kanaka i ka nui o ke koko e like me ka mea i hoʻāʻo ʻia i ka vitro.
Ua hōʻike pū kekahi ʻo Lycorine i ka hana antiviral ikaika e kūʻē iā SARS-CoV.3 Ua hōʻike ʻia kekahi mau hōʻike i hala aku nei e like me ka nui o nā hana antiviral a Lycorine a ua hōʻike ʻia ua hōʻike ʻia kahi hana pāpā ma ka maʻi ʻo Herpes Simplex (ʻano I) [x] a me ka Poliomyelitis. virus pū kekahi. [xi]
"ʻO nā mea kanu ʻē aʻe i hōʻike ʻia e hōʻike ana i ka hana antiviral e kūʻē iā SARS-CoV ʻo Lonicera japonica (Japanese Honeysuckle) a me ka mea kanu Eucalyptus i ʻike nui ʻia, a me Panax ginseng (kahi aʻa) ma o kāna mea hana ʻo Ginsenoside-Rb1." [Xii]
Hōʻike nā hōʻike mai nā noiʻi i ʻōlelo ʻia ma luna aʻe a me nā noiʻi ʻē aʻe ma ka honua holoʻokoʻa i ka nui o nā mea kanu lāʻau i hōʻike i nā hana antiviral e kūʻē i nā coronaviruses [xiii] [xiv] a me kā lākou ʻano hana nui o ka hana me he mea lā ke kāohi ʻia o ka hoʻopili hou ʻana o viral. ua hoʻohana nui ʻia i nā lāʻau lapaʻau Kina no ka mālama ʻana i ka SARS ma nā hanana he nui. [xvi] Eia nō naʻe ʻaʻohe hōʻike nui e pili ana i ka pono olakino o kēia mau mea no nā mea maʻi ʻo Covid-19.
Hiki paha i nā mea kanu lāʻau ke lilo i moho no ka hoʻomohala ʻana i nā lāʻau antiviral hou no ka pale ʻana a mālama ʻana paha i ka SARS?
NĀ PALAPALA: Ua kākau ʻia kēia ʻatikala no ka ʻike wale nō a ʻaʻole ia i mea e pani i ka ʻōlelo aʻoaʻo olakino, ka hōʻailona a me ka lāʻau. Inā manaʻo ʻoe he mau hōʻailona paha kāu e pili ana i nā Covid-19 a i ʻole nā maʻi ʻē aʻe, e kāhea koke i kāu kauka.
[i] Zhou, P., Yang, X., Wang, X. et al., 2020. ʻO kahi maʻi kūpilikiʻi e pili ana i kahi coronavirus hou o ke kumu ʻōpeʻapeʻa paha. ʻAno 579, 270–273 (2020). https://doi.org/10.1038/s41586-020-2012-7
[ii] Andersen, KG, Rambaut, A., Lipkin, WI, Holmes, EC a me Garry, RF, 2020. Ke kumu pili o SARS-CoV-2. Lapaʻau Kūlohelohe, pp.1-3.
[iii] CDC SARS Pane kuhikuhi manawa. Loaʻa ma https://www.cdc.gov/about/history/sars/timeline.htm. Loaʻa ʻia
[iv] Li, SY, Chen, C., Zhang, HQ, Guo, HY, Wang, H., Wang, L., Zhang, X., Hua, SN, Yu, J., Xiao, PG and Li, RS, 2005. ʻIke ʻia o nā hui kūlohelohe me nā hana antiviral e kūʻē i ka coronavirus e pili ana iā SARS. Nānā Antiviral, 67 (1), pp.18-23.
[v] Cinatl, J., Morgenstem, B. a me Bauer, G., 2003. ʻO Glycyrrhizin, kahi ʻeleu hana o nā aʻa licorice a me ka replication o coronovirus e pili ana iā SARS. Lancet, 361 (9374), pp.2045-2046.
[vi] Hoever, G., Baltina, L., Michaelis, M., Kondratenko, R., Baltina, L., Tolstikov, GA, Doerr, HW a me Cinatl, J., 2005. Hana Antiviral o Glycyrrhizic Acid Derivatives e kūʻē iā ʻO SARS− Coronavirus. Ka puke pai o ke kelekema lāʻau, 48 (4), pp.1256-1259.
[vii] Chen, F., Chan, KH, Jiang, Y., Kao, RYT, Lu, HT, Fan, KW, Cheng, VCC, Tsui, WHW, Hung, IFN, Lee, TSW a me Guan, Y., 2004. I ka vitro susceptibility o 10 clinical isolates o ka SARS coronavirus i koho i nā antiviral compound. Ka Nūpepa o Virology Haumāna, 31 (1), pp.69-75.
[viii] Kitamura, K., Honda, M., Yoshizaki, H., Yamamoto, S., Nakane, H., Fukushima, M., Ono, K. and Tokunaga, T., 1998. Baicalin, an inhibitor of Hana HIV-1 i vitro. Nānā Antiviral, 37 (2), pp.131-140.
[ix] Li, BQ, Fu, T., Dongyan, Y., Mikovits, JA, Ruscetti, FW a me Wang, JM, 2000. Hoʻopili ka Flavonoid baicalin i ka maʻi HIV-1 ma ke kiʻekiʻe o ke komo ʻana o ka maʻi viral. Nā kamaʻilio noiʻi biochemical a me biophysical, 276 (2), pp.534-538.
[x] Renard-Nozaki, J., Kim, T., Imakura, Y., Kihara, M. a me Kobayashi, S., 1989. Ka hopena o nā alkaloids i hoʻokaʻawale ʻia mai Amaryllidaceae ma ka maʻi herpes simplex. ʻImi i ka virology, 140, pp.115-128.
[xi] Ieven, M., Vlietinick, AJ, Berghe, DV, Totte, J., Dommisse, R., Esmans, E. a me Alderweireldt, F., 1982. Kanu antiviral mea kanu. III. Hoʻokaʻawale o nā alkaloids mai Clivia miniata Regel (Amaryl-lidaceae). Ka Nūpepa o nā Huahana Kūlohelohe, 45 (5), pp.564-573.
[xii] Wu, CY, Jan, JT, Ma, SH, Kuo, CJ, Juan, HF, Cheng, YSE, Hsu, HH, Huang, HC, Wu, D., Brik, A. and Liang, FS, 2004 . Nā mole liʻiliʻi e kuhikuhi ana i ka maʻi hanu koʻikoʻi o ka coronavirus kanaka. Nā hana o ka National Academy of Science, 101 (27), pp.10012-10017.
[xiii] Wen, CC, Kuo, YH, Jan, JT, Liang, PH, Wang, SY, Liu, HG, Lee, CK, Chang, ST, Kuo, CJ, Lee, SS and Hou, CC, 2007. kikoʻī nā terpenoids a me nā lignoids i nā hana antiviral ikaika e kūʻē i ka coronavirus respiratory respiratory koʻikoʻi. Ka puke pai o ke kelekema lāʻau, 50 (17), pp.4087-4095.
[xiv] McCutcheon, AR, Roberts, TE, Gibbons, E., Ellis, SM, Babiuk, LA, Hancock, REW and Towers, GHN, 1995. Nānā Antiviral o nā mea kanu lāʻau British Columbian. Ka Nūpepa o Ethnopharmacology, 49 (2), pp.101-110.
[xv] Jassim, SAA a me Naji, MA, 2003. Nā mea hana antiviral novel: kahi kuanaʻike mea kanu lāʻau. Ka puke pai o microbiology noi, 95 (3), pp.412-427.
[xvi] Luo, H., Tang, QL, Shang, YX, Liang, SB, Yang, M., Robinson, N. and Liu, JP, 2020. Hiki ke hoʻohana ʻia ka lāʻau Kina no ka pale ʻana i nā maʻi virus corona 2019 (COVID -19)? He loiloi i nā moʻolelo kahiko, nā hōʻike noiʻi a me nā papahana pale i kēia manawa. Ka Nūpepa Kina o ka Medicine Integrative, pp.1-8.
E like me ka hana maʻamau me ka ʻaneʻane o nā pūnaewele ʻoihana, hoʻohana kā mākou pūnaewele i nā kuki, nā faila liʻiliʻi i hoʻoiho ʻia i kāu hāmeʻa, e hoʻomaikaʻi i kāu ʻike.
Hōʻike kēia palapala i ka ʻike a lākou e hōʻiliʻili ai, pehea mākou e hoʻohana ai a no ke aha mākou e mālama ai i kēia mau kuki i kekahi manawa. E māhele pū mākou pehea e hiki ai iā ʻoe ke pale aku i kēia mau kuki mai ka mālama ʻia ʻana akā e hoʻoliʻiliʻi paha kēia a i ʻole 'haki' i kekahi mau mea o nā pono pūnaewele.
Hoʻohana mākou i nā kuki no nā kumu like ʻole i hōʻike ʻia ma lalo. Minamina, i ka hapanui o nā hihia ʻaʻohe koho maʻamau ʻoihana no ka hōʻino ʻana i nā kuki me ka ʻole o ka hoʻopau ʻole i nā hana a me nā hiʻohiʻona a lākou e hoʻohui ai i ka pūnaewele. Paipai ʻia ʻoe e haʻalele i nā kuki āpau inā ʻaʻole ʻoe e maopopo inā pono ʻoe iā lākou ʻaʻole paha, inā e hoʻohana ʻia lākou e hāʻawi i kahi lawelawe āu e hoʻohana ai.
Hiki iā ʻoe ke pale i ka hoʻonohonoho ʻana o nā kuki ma o ka hoʻoponopono ʻana i nā hoʻonohonoho ma kāu polokalamu kele pūnaewele (ʻike i kāu koho "Kōkua" i kāu polokalamu kele pūnaewele pehea e hana ai i kēia). E makaʻala i ka hiki ʻole i nā kuki ke hoʻololi i ka hana o kēia a me nā pūnaewele ʻē aʻe āu e kipa aku ai. No laila, paipai ʻia ʻaʻole ʻoe e hoʻopio i nā kuki.
I kekahi mau hihia kūikawā hoʻohana mākou i nā kuki i hāʻawi ʻia e nā ʻaoʻao ʻekolu i hilinaʻi ʻia. Hoʻohana kā mākou pūnaewele i ka [Google Analytics] ʻo ia kekahi o nā hōʻoia aniani ākea ākea a hilinaʻi ʻia ma ka pūnaewele no ke kōkua ʻana iā mākou e hoʻomaopopo pehea e hoʻohana ai i ka pūnaewele a me nā ala e hiki ai iā mākou ke hoʻomaikaʻi i kāu ʻike. Hiki i kēia mau kuki ke nānā i nā mea e like me ka lōʻihi o kāu lilo ma ka pūnaewele a me nā ʻaoʻao āu e kipa aku ai i hiki iā mākou ke hoʻomau i ka hana ʻana i ka ʻike i loko. No ka ʻike hou aku e pili ana i nā kuki Google Analytics, e ʻike i ka ʻaoʻao ʻaoʻao Google Analytics.
ʻO Google Analytics kahi hoʻopihapiha hoʻopuka a Google e kōkua ai i kā mākou pūnaewele e hoʻomaopopo i ka pili ʻana o ka poʻe kipa me kā lākou waiwai. Hiki iā ia ke hoʻohana i kahi set o nā kuki e hōʻiliʻili i ka ʻike a hōʻike i nā helu helu hoʻohana pūnaewele me ka ʻole o ka ʻike pilikino ʻana i kēlā me kēia mea kipa iā Google. ʻO ka kuki nui i hoʻohana ʻia e Google Analytics ʻo ia ka cookie '__ga'.
Ma waho aʻe o ka hōʻike ʻana i nā helu helu hoʻohana pūnaewele, hiki ke hoʻohana ʻia ʻo Google Analytics, me kekahi o nā kuki hoʻolaha, e kōkua e hōʻike i nā hoʻolaha kūpono aʻe ma nā waiwai Google (e like me Google Search) a ma o ka pūnaewele a me ke ana ʻana i nā pilina me nā hoʻolaha a Google .
Hoʻohana o nā IP Addresses. ʻO kahi helu IP kahi helu helu e hōʻike ana i kāu hāmeʻa ma ka Pūnaewele. Hiki iā mākou ke hoʻohana i kāu IP a me kāu ʻano polokalamu kele pūnaewele e kōkua i ke kālailai ʻana i nā lauana hoʻohana a ʻike i nā pilikia ma kēia pūnaewele a hoʻomaikaʻi i ka lawelawe a mākou e hāʻawi aku ai iā ʻoe. Akā me ka ʻole o ka ʻike hou aʻe ʻaʻole e hōʻike kāu IP address iā ʻoe ma ke ʻano he hoʻokahi kanaka.
Kāu Koho. Ke hiki aku ʻoe i kēia pūnaewele, hoʻouna ʻia kā mākou mau kuki i kāu pūnaewele pūnaewele a mālama ʻia i kāu polokalamu. Ma ka hoʻohana ʻana i kā mākou pūnaewele, ʻae ʻoe i ka hoʻohana ʻana o nā kuki a me nā ʻenehana like.
Lana ka manaʻo i ka ʻikepili ma luna aʻe i wehewehe i nā mea nāu. E like me ka mea i ʻōlelo ʻia ma mua, inā ʻaʻole ʻoe e ʻike inā makemake ʻoe e ʻae i nā kuki ʻaʻole ʻole, ʻoi aku ka maikaʻi o ka waiho ʻana o nā kuki i hiki ke hui pū me kekahi o nā hiʻohiʻona āu e hoʻohana ai ma kā mākou pūnaewele. Eia nō naʻe, inā ʻoe e ʻimi nei i ka ʻike hou aku, a laila e ʻoluʻolu e kāhea iā mākou ma o ka leka uila ma [ka pale ʻana o ka leka uila]
Pono e ʻae ʻia ka cookie pono i nā manawa āpau i hiki ai iā mākou ke mālama i kāu mau makemake no nā hoʻonohonoho kuki.
Inā hōʻole ʻoe i kēia kuki, ʻaʻole hiki iā mākou ke mālama i kāu mau makemake. ʻO ka manaʻo kēia i kēlā me kēia manawa āu e kipa ai i kēia pūnaewele pono ʻoe e hoʻohana a hoʻopau hou paha i nā kuki.
Ka manawa o ka manawa: Apr-10-2020