N-Methyl-DL-Aspartic Acid

Short Description:

N-Methyl-DL-Aspartic Acid (NMA) is a naturally occurring amino acid derivative in animals and is a homologue of L-Glutamic Acid, an important excitatory neurotransmitter in the mammalian central nervous system. It is noteworthy for its neurogenic properties, which means that it promotes the growth and development of brain cells. This amino acid derivative has a place in protein synthesis and neurotransmitters in the brain such as glutamate and aspartate. It is an amino acid derivative and excitatory neurotransmitter. Moderate amounts of NMDA can significantly promote the secretion of animal growth hormon(GH) and increase the level of GH in the blood. In addition, N-methyl-DL-aspartic acid can promote skeletal muscl*e growth*and increase muscle mass and strength.

N-Methyl-DL-Aspartic Acid (NMDA) is an amino acid derivative naturally occurring in animals, and is an important excitatory neurotransmitter L-glutamic acid homologue in the mammalian central nervous system.N-Methyl-DL-Aspartic Acid (NMA) is an amino acid derivative naturally occurring in animals and a homolog of L-glutamic acid, an important excitatory neurotransmitter in the mammalian central nervous system. It’s worth mentioning that it has neurogenic properties, which means it promotes the growth and development of brain cells. This amino acid derivative plays a crucial role in the synthesis of proteins and the regulation of neurotransmitters in the brain, such as glutamate and aspartate. It is an amino acid derivative and excitatory neurotransmitter. An appropriate amount of NMDA can affect the body’s endocrine system, especially significantly promote the secretion of animal growth hormone (GH), increasing the level of GH in the blood. In addition, N-methyl-DL-aspartic acid can promote skeletal muscle growth and increase muscle mass and strength. N-methyl-DL-aspartic acid can also improve immunity and enhance the body’s resistance and immune function.

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Product Detail

Product Tags

Product Name:N-Methyl-DL-Aspartic Acid

CAS No:17833-53-3

Other Name:N-methyl-D,L-aspartate;

N-methyl-D,L-aspartic acid;

L-Aspartic acid, N-methyl;

DL-Aspartic acid, N-methyl;

DL-2-METHYLAMINOSUCCINIC ACID;

Specifications: 98.0%

Colour: White powder with characteristic odor and taste

GMO Status:GMO Free

Packing: in 25kgs fiber drums

Storage:Keep container unopened in cool, dry place,Keep away from strong light

Shelf Life:24 months from date of production

N-Methyl-DL-Aspartic Acid (NMA) | NMDA Receptor Agonist for Neuroscience Research
Product Code: NMA-2025 | CAS: 17833-53-3 | Purity: ≥98%

Product Overview

N-Methyl-DL-Aspartic Acid (NMA), also known as DL-2-Methylaminosuccinic Acid, is a synthetic glutamate analogue and a potent NMDA receptor agonist. It is widely utilized in neurobiological research to study synaptic plasticity, neuronal excitotoxicity, and disease models such as neuropathic pain and retinal degeneration .

Key Features

High Purity: Rigorously tested via HPLC (≥98% purity) to ensure consistency in experimental outcomes.
Versatile Applications: Ideal for in vitro and in vivo studies, including fictive locomotion induction in spinal cord networks , maternal behavior neural circuitry analysis , and retinal damage modeling .
Global Standards Compliance: Sourced from ISO-certified facilities, with full traceability and MSDS documentation.

Applications in Research

Neuropharmacology:
- Elicits fictive locomotion in isolated spinal cords when co-applied with 5-HT (e.g., 10 µM NMA + 10 µM 5-HT) .
- Facilitates NMDA receptor activation in studies of excitotoxicity and neuroprotection .
Behavioral Neuroscience:
- Used in excitotoxic lesions (e.g., MPOA ablation) to investigate maternal behavior mechanisms .
Disease Modeling:
- Induces retinal cell degeneration in animal models for studying neurodegenerative disorders .

Technical Specifications

Parameter	Detail
Molecular Formula	C₅H₉NO₄
Molecular Weight	147.13 g/mol
Synonyms	DL-2-Methylaminosuccinic Acid, NMA
Storage	Store at -20°C in dry conditions
Packaging Options	10 mg, 50 mg, 100 mg (Customizable)

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