I-N-Methyl-DL-Aspartic Acid

Isithombe Esifakiwe se-N-Methyl-DL-Aspartic Acid
  • I-N-Methyl-DL-Aspartic Acid

Incazelo emfushane:

I-N-Methyl-DL-Aspartic Acid (NMA) itholakala ngokwemvelo ephuma ku-amino acid ezilwaneni futhi iyi-homologue ye-L-Glutamic Acid, i-neurotransmitter ebalulekile ethokozisayo ohlelweni lwezinzwa oluncelisayo olumaphakathi. Kuyaphawuleka ngezakhiwo zayo ze-neurogenic, okusho ukuthi ikhuthaza ukukhula nokuthuthukiswa kwamangqamuzana obuchopho. Lokhu okuphuma ku-amino acid kunendawo ku-protein synthesis kanye nama-neurotransmitters ebuchosheni njenge-glutamate ne-aspartate. Kuyi-neurotransmitter ephuma ku-amino acid kanye ne-excitatory. Amanani alinganiselwe we-NMDA angakhuthaza kakhulu ukukhishwa kwe-hormon yezilwane (GH) futhi andise izinga le-GH egazini. Ngaphezu kwalokho, i-N-methyl-DL-aspartic acid ingakhuthaza ukukhula kwemisipha yamathambo* futhi yandise imisipha namandla.

I-N-Methyl-DL-Aspartic Acid (NMDA) iphuma ku-amino acid eyenzeka ngokwemvelo ezilwaneni, futhi iyi-neurotransmitter ebalulekile ye-L-glutamic acid homologue ohlelweni lwezinzwa ezincelisayo. i-neurotransmitter ohlelweni lwezinzwa oluncelisayo. Kuhle ukusho ukuthi inezici ze-neurogenic, okusho ukuthi ikhuthaza ukukhula nokuthuthukiswa kwamangqamuzana obuchopho. Lokhu okuphuma ku-amino acid kudlala indima ebalulekile ekuhlanganiseni amaprotheni nasekulawuleni ama-neurotransmitters ebuchosheni, njenge-glutamate ne-aspartate. Kuyi-neurotransmitter ephuma ku-amino acid kanye ne-excitatory. Inani elifanele le-NMDA lingathinta uhlelo lwe-endocrine lomzimba, ikakhulukazi ukukhuthaza ukukhiqizwa kwe-hormone yokukhula kwezilwane (GH), okwandisa izinga le-GH egazini. Ngaphezu kwalokho, i-N-methyl-DL-aspartic acid ingakhuthaza ukukhula kwemisipha yamathambo futhi yandise imisipha namandla. I-N-methyl-DL-aspartic acid nayo ingathuthukisa ukungatheleleki komzimba futhi ithuthukise ukuphikiswa komzimba nokusebenza komzimba.

 


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    Imininingwane Yomkhiqizo

    Omaka bomkhiqizo

    Igama Lomkhiqizo:I-N-Methyl-DL-Aspartic Acid

    Inombolo ye-CAS:17833-53-3

    Elinye Igama:N-methyl-D,L-aspartate;

    I-N-methyl-D, L-aspartic acid;

    L-Aspartic acid, N-methyl;

    I-DL-Aspartic acid, i-N-methyl;

    I-DL-2-METHYLAMINOSUCCINIC ACID;

    Imininingwane: 98.0%

    Umbala: Impushana emhlophe enephunga nokunambitha

    Isimo se-GMO:GMO Mahhala

    Ukupakisha: ku-25kgs fiber drums

    Isitoreji: Gcina isitsha singavulwa endaweni epholile, eyomile, gwema ukukhanya okuqinile

    Impilo Yeshelufu: Izinyanga ezingama-24 kusukela ngosuku lokukhiqiza

     

    I-N-Methyl-DL-Aspartic Acid (NMA) |I-NMDAI-Receptor agonist yocwaningo lwe-Neuroscience
    Ikhodi Yomkhiqizo: NMA-2025 | I-CAS:17833-53-3| Ubumsulwa: ≥98%

    Uhlolojikelele Lomkhiqizo

    I-N-Methyl-DL-Aspartic Acid (NMA), eyaziwa nangokuthi i-DL-2-Methylaminosuccinic Acid, iyi-analogue yokwenziwa ye-glutamate kanye ne-agonist enamandla ye-NMDA yokwamukela. Isetshenziswa kabanzi ocwaningweni lwe-neurobiological ukutadisha ipulasitiki ye-synaptic, i-neuronal excitotoxicity, namamodeli wezifo afana nobuhlungu be-neuropathic kanye nokuwohloka kwe-retina.

    Izici Eziyinhloko

    • Ukuhlanzeka Okuphezulu: Kuhlolwe ngokuqinile nge-HPLC (≥98% ubumsulwa) ukuze kuqinisekiswe ukungaguquguquki emiphumeleni yokuhlola.
    • Izicelo Ezihlukahlukene: Ilungeleku-vitrofuthinge vivoizifundo, okuhlanganisa ukungeniswa kwe-locomotion okungelona iqiniso kumanethiwekhi omgogodla, ukuhlaziya ukuziphatha komama kwe-neural circuitry, kanye nokumodela kokulimala kwe-retina.
    • Ukuthobela Amazinga Omhlaba: Kutholwe ezikhungweni ezigunyazwe nge-ISO, ezinokulandeleka okugcwele kanye nemibhalo ye-MSDS.

    Izicelo Ocwaningweni

    1. I-Neuropharmacology:
      • Iletha ukuhamba okungelona iqiniso ezintanjeni zomgogodla ezingazodwa uma isetshenziswa ngokuhlanganyela ne-5-HT (isb, 10 µM NMA + 10 µM 5-HT) .
      • Yenza kusebenze i-NMDA receptor ezifundweni ze-excitotoxicity kanye neuroprotection.
    2. I-Behavioral Neuroscience:
      • Kusetshenziswa izilonda ze-excitotoxic (isb, ukukhishwa kwe-MPOA) ukuze kuphenywe izindlela zokuziphatha komama .
    3. Imodeli Yezifo:
      • Idala ukuwohloka kwamaseli e-retina kumamodeli ezilwane okutadisha ukuphazamiseka kwe-neurodegenerative.

    Imininingwane Yezobuchwepheshe

    Ipharamitha Imininingwane
    I-Molecular Formula C₅H₉NO₄
    Isisindo samangqamuzana 147.13 g/mol
    Omqondofana I-DL-2-Methylaminosuccinic Acid, NMA
    Isitoreji Gcina ku -20 ° C ezimweni ezomile
    Izinketho zokupakisha 10 mg, 50 mg, 100 mg (Okungenziwa ngokwezifiso)

    Kungani Khetha Thina?

    • Iminyaka Engu-15+ Yobungcweti: Njengomphakeli othembekile kumakhemikhali ocwaningo, sibeka phambili impendulo esheshayo nezixazululo eziklanyelwe amaklayenti ezemfundo nawezimboni.
    • Ukufinyeleleka: Izincazelo zomkhiqizo zakhiwe ngamagama angukhiye (I-agonist ye-NMDA, ikhemikhali yocwaningo lwe-neuroscience) ukuthuthukisa ukubonakala ku-Google nezizindalwazi zesayensi.

    Imikhiqizo Ehlobene

    • I-5-Hydroxytryptamine (5-HT): Ukusebenzisa i-Synergistic ne-NMA ezifundweni ze-locomotion.
    • I-Calcium 2AEP ne-Astaxanthin: Hlola iphothifoliyo yethu ehlanganisiwe ye-neuroprotective.
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