Product Name:7,8-Dihydroxyflavone

CAS No:38183-03-87

Other Name:7,8-DIHYDROXYFLAVONE;7,8-dihydroxy-2-phenyl-4-benzopyrone;

DIHYDROXYFLAVONE, 7,8-(RG);7,8-Dihydroxyflavone hydrate;

7,8-dihydroxy-2-phenyl-1-benzopyran-4-one,,8-Dihydroxyflavone (7,8-DHF)

Specifications: 98.0%

Colour: Yellow powder with characteristic odor and taste

GMO Status:GMO Free

Packing: in 25kgs fiber drums

Storage:Keep container unopened in cool, dry place,Keep away from strong light

Shelf Life:24 months from date of production

7,8-Dihydroxyflavone, also known as 7,8-DHF, is a naturally occurring flavonoid found in a variety of plants, including Tridacna tridacna. Known for its antioxidant and neurotrophic properties, one of the most interesting aspects of 7,8-dihydroxyflavone is its potential to support brain health and enhance cognitive function.

7,8-Dihydroxyflavone (7,8-DHF) is a potent and selective TrkB receptor agonist (Kd≈320 nM). TrkB receptor is the main signal receptor of brain-derived neurotrophic factor. 7,8-Dihydroxyflavone (7,8-DHF) is a potential nootropic that may improve overall brain health, mood, and cognitive function. It may also be of benefit for several neurodegenerative and neurodevelopmental disorders, as well as obesity and elevated blood pressure

7,8-Dihydroxyflavone, also known as 7,8-DHF, is a naturally occurring flavonoid found in a variety of plants, including Tridacna tridacna. Known for its antioxidant and neurotrophic properties, one of the most interesting aspects of 7,8-dihydroxyflavone is its potential to support brain health and enhance cognitive function. Research shows that this compound acts as a potent neurotrophin, stimulating the growth and survival of neurons in the brain. Studies in laboratory animals have shown that 7,8-DHF significantly improves memory and learning abilities. By promoting the formation of new synaptic connections and enhancing communication between brain cells, this compound promises to unlock our cognitive potential. Additionally, 7,8-dihydroxyflavone interacts with the brain’s serotonin receptors, which are involved in mood regulation. By modulating these receptors, it may be able to reduce symptoms of anxiety and depression.

Function of 7,8-Dihydroxyflavone
1) Improve Memory and Learning
2) Promote Brain Repair
7,8-DHF promoted the repair of damaged neurons .
3) Be Neuroprotective
4) Has Antioxidant Effects
5) Has Anti-Inflammatory Effects
7,8-DHF decreases the release of inflammatory factors in brain cells by blocking NF-κB .
6) 7,8-DHF has a strong therapeutic effect on Alzheimer’s disease, and can inhibit obesity by activating muscle TrkB..

Application of 7,8-Dihydroxyflavone
7,8-Dihydroxyflavone (7,8-DHF) is a naturally occurring flavone found in Godmania aesculifolia, Tridax procumbens, and primula tree leaves. It has been found to act as a potent and selective small-molecule agonist of the tropomyosin receptor kinase B (TrkB) (Kd ≈ 320 nM), the main signaling receptor of the neurotrophin brain-derived neurotrophic factor (BDNF). 7,8-DHF is both orally bioavailable and able to penetrate the blood-brain barrier. A prodrug of 7,8-DHF with greatly improved potency and pharmacokinetics, R7, is under development for the treatment of Alzheimer’s disease…