|Product Name||Thymol Bulk Powder|
|Other Name||5-methyl-2-isopropylphenol; Thyme camphor; M-thymol; P-cymen-3-ol; 3-hydroxy p-isopropyl toluene; Thyme brain; 2-Hydroxy-1-isopropyl-4-methylbenzene;|
|Latin Name||Thymus vulgaris L., Lamiaceae|
|Molecular Weight||150.2 g/mol|
|Boiling Point||49~51 °C|
|Benefits||Flavoring agent, Antioxidant,Antibacterial, Antifungal, Antiseptic|
What is thymol?
Thymol is found in thyme oil, a natural monoterpenoid phenol derivative of p-Cymene, isomeric with carvacrol. Its structure is similar to carvol, and it has hydroxyl groups at different positions of the phenol ring, one of the most important dietary components in thyme species. Thymol powder was usually extracted from Thymus vulgaris (common thyme), ajwain, and various other plants as a white crystalline substance with a pleasant aromatic odor and strong antiseptic properties.
Thymol Natural Sources
Thyme is a medicinal plant with a variety of therapeutic properties. This plant originating in the Mediterranean region is usually used as a cooking herb with a long medicinal history. Thyme is one of the main components of thyme essential oil(Thymus vulgaris L., Lamiaceae), accounting for about 50%~75% according to the quality of different raw materials.
Of course, thyme can also be found in other plants, like Ocimum gratissimum、Origanum vulgare、Lippia multiflora、Centipeda minima、Satureja hortensis, and Nigella sativa seeds.
Thymol Powder Manufacturing Process
In the past, the commercial source of thymol was extracted from thyme. However, the low yield, high cost, and high environmental pressure of thymol removed led to the increased market price of thyme, limiting commercial development and market space.
Therefore, Cima Science solves the above problems using synthesis. The synthesis method is mainly Fourier alkylation: thyme is produced under pressure using m-cresol, chloropropane, and other isopropyl substances, propylene or isopropanol as raw materials.
Thymol is a versatile compound that has a wide range of applications. It is used in food and daily chemical products, such as mouthwashes and dental gels. Thymol can also be used as an antibacterial agent, helping to prevent the spread of bacteria in the mouth. In addition, it can be used to coat food products, acting as an antimicrobial agent to inhibit bacterial growth. Furthermore, thymol is also used as a dietary supplement due to its antioxidant and anti-inflammatory properties. All of these examples highlight the versatility of thymol, making it an extremely popular ingredient in many products on the market today.
Thymol is a natural monoterpene phenol derivative, a kind of cymene C10H14O. It is isomeric with carvol and exists in thyme oil. It is extracted from thyme and other plants as a white crystalline substance and has a pleasant aromatic smell and strong antiseptic properties. Thymol separated from the essential oil always has the flavor of carvol, which is described as a more dry medicinal phenol tar flavor than thymol itself. Thymol also provides the unique and rich taste of cooking vanilla thyme.
Thymol can interfere with extracellular and intracellular virus levels when entering a host and has demonstrated antiviral activities against influenza, HSV-1, HSV-2, and HIV-1. Drug resistance limits the ability to combat viral diseases globally. Thymol’s anti-biofilm effect helps to reduce this challenge.
Cryptococcus fungi cause a systemic fungal disease known as cryptococcosis, which can affect the respiratory and nervous systems. Thymol has been shown to have strong antifungal capabilities, inhibiting biofilm formations and damaging Cryptococcus cell membrane structure leading to cell death. Dipalmitoyl phosphatidylcholine (DPPC) reduction of cell membrane elasticity further contributes to the effectiveness of thymol against Cryptococcus.
Other pharmacological effects
Thymol is a powerful antioxidant, with anti-proliferation and pro-apoptosis properties on various cancer cells, as well as anti-inflammatory, anti-injury, anti-asthma, expectorant, antiseptic, immune regulation, anti-spasmodic and hyperlipidemia effects.
Thymol Side Effects
Thymol has been used in many products and applications over the years, and with the addition of government licensing regulations it remains a safe ingredient to use. There have been no reported side effects from using thymol in food products.
The Chinese government has set out clear dosage regulations for the use of thymol in food products. For chewing gum, up to 100 mg/kg can be used; for cold drinks, 44 mg/kg; for soft drinks, between 2.5 and 11 mg/kg; for candy, 9.4 mg/kg; and for baked goods, between 5.0 and 6.5 mg/kg. There is no clear dose limit set out for its use in other application fields.