Product Name:YDL223C (HBT1) Powder

Other Name:HBT1,YDL223C

CAS No:489408-02-8

Specifications: 99.0%

Colour: Light yellow solid with characteristic odor and taste

GMO Status:GMO Free

Packing: in 25kgs fiber drums

Storage:Keep container unopened in cool, dry place,Keep away from strong light

Shelf Life:24 months from date of production

HBT1 is a molecule that can only bind to a specific site on the AMPA-R protein when glutamate is present, and this binding helps regulate the activity of the protein.  AMPA receptors are expressed throughout the central nervous system and play important roles in neuronal communication, sensory processing, learning, memory, and synaptic plasticity.  AMPA receptors are major contributors to excitatory neurotransmission, mediate rapid, rapidly desensitizing excitation at many synapses, and are involved in early responses to glutamate in synaptic regions.  AMPA receptors are often co-expressed with NMDA receptors at synapses, and together they promote synaptic plasticity processes involved in learning, memory, excitotoxicity, and neuroprotection. Brain-derived neurotrophic factor (BDNF) is a neurotrophic factor that plays an important role in the maintenance and expansion of neurons and has powerful and numerous effects on the proliferation, differentiation, survival and death of neuronal and non-neuronal cells. , a neurotransmitter modulator that contributes to neuronal plasticity in learning and memory. Therefore, it is essential for the health and well-being of the nervous system.

Functions:

1. Yeast genomic knockout strain
   2. Shmoo tip protein, substrate of Hub1p ubiquitin-like protein; mutants are defective for mating projection formation, thereby
   implicating Hbt1p in polarized cell morphogenesis; HBT1 has a paralog, YNL195C, that arose from the whole genome duplication
   3. Applied in pharmaceutical field.
   4. Enhance mental intelligence.
   5. Boost memory and leaning capabilities.
   6. Enhance motivation level.
   7. Enhance the control of cortical/subcortical brain mechanism.
   8. Improve sensory perception.
   9. Improve brain power to solve problems and protect it from any chemical or physical.

Applications:

HBT1 is a novel potent AMPA-R [alpha-amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid (AMPA) receptor] potentiator with lower agonistic effect compared with LY451395 and OXP1, it induces production of brain-derived neurotrophic factor (BDNF) and exhibits little agonistic effect in primary neurons. HBT1 binds to ligand-binding domain of AMPA-R in glutamate dependent manner