Diosmetin 98%

Short Description:

Diosmetin, CAS 520-34-3, is the aglycone of the flavonoid glycoside diosmin which occurs naturally in citrus fruits. In citrus, there are already many active ingredients commercially available as bulk raw powders, such as hesperidin, diosmin, hesperitin, synephrine, neohesperidin, naringin, methyl hesperidin, methyl hesperidin chalcone, naringin dihydrochalcone, and citrus bioflavonoid, etc. However, diosmetin may be the least popular one among them. All these flavones are generally regarded as safe (GRAS) and used in dietary supplemets formulas, but diosmetin is too new to get noticed.Scientifically known as 3′, 5, 7-trihydroxy-4′-methoxyflavone-7-ramnoglucoside, diosmetin is an O-methylated flavone recognized for its tumor-suppressing capabilities. Pharmacologically, diosmetin is reported to exhibit anticancer, antimicrobial, antioxidant, oestrogenic and anti-inflamatory activities.


  • FOB Price: US $0.5 - 9,999 / KG
  • Min.Order Quantity: 1 KG
  • Supply Ability: 10000 KG/per Month
  • Port: SHANGHAI/BEIJING
  • Payment Terms: L/C,D/A,D/P,T/T
  • Product Detail

    Product Tags

    Diosmetin, CAS 520-34-3, is the aglycone of the flavonoid glycoside diosmin which occurs naturally in citrus fruits. In citrus, there are already many active ingredients commercially available as bulk raw powders, such as hesperidin, diosmin, hesperitin, synephrine, neohesperidin, naringin, methyl hesperidin, methyl hesperidin chalcone, naringin dihydrochalcone, and citrus bioflavonoid, etc. However, diosmetin may be the least popular one among them. All these flavones are generally regarded as safe (GRAS) and used in dietary supplemets formulas, but diosmetin is too new to get noticed.Scientifically known as 3′, 5, 7-trihydroxy-4′-methoxyflavone-7-ramnoglucoside, diosmetin is an O-methylated flavone recognized for its tumor-suppressing capabilities. Pharmacologically, diosmetin is reported to exhibit anticancer, antimicrobial, antioxidant, oestrogenic and anti-inflamatory activities.

    Product Name:Diosmetin 98%

    Botanical Source:Citrus aurantium L , Lemon extract

    CAS No:520-34-3

    Plant Part Used:Fruit

    Ingredient: Thymoquinone

    Assay: Diosmetin  98% 99% by HPLC

    Colour:Yellow brown to Brown fine powder with characteristic odor and taste

    GMO Status:GMO Free

    Packing: in 25kgs fiber drums

    Storage:Keep container unopened in cool, dry place,Keep away from strong light

    Shelf Life:24 months from date of production

     

    Diosmetin benefits

    Diosmetin is the active metabolite of diosmin, and they share similar molecular structures. Diosmin is rapidly hydrolyzed to diosmetin in the intestine with the help of intestinal microflora enzymes. In this sense, the major benefits of diosmin is also diosmetin’s heathy benefits, such as treat chronic venous insufficiency, hemorrhoids, lymphedema, and varicose veins, etc., and diosmetin is for more efficient and better than diosmin and micronized diosmin.

     

    Healthy Veins and Legs

    As a more efficient diosmin form, diosmetin is a bioflavonoid that is able to reduce the visible signs of varicose and spider veins, as well as alleviate occasional swelling in the legs and ankles known as “heavy legs”.

    Diosmetin also enhances the overall health and tone of small veins & capillaries, especially in the legs.

    Anti-caner

    Diosmetin functions as a human CYP1A enzyme activity inhibitor. Diosmetin inhibits carcinogen activation by inhibiting the CYP1A1 enzyme. Diosmetin has anti-mutagenic and anti-allergic characteristics in vitro, and inhibits tumor growth and protect tumor-induced apoptosis in vivo.

    Diosmetin may be also beneficial to treat various inflammations and viral infections. In addition, luteolin and diosmin/diosmetin as novel STAT3 inhibitors for treating autism.

    Side effects of diosmetin

    For the time being, no supplements containing diosmetin is on the market. No negative effects are reported.

    Diosmetin Dosage

    No recommended daily dosage for diosmetin at present. No supplements or medicines containing diosmetin are available. Diosmetin is used for reference standards, pharmacological research, food research, cosmetic research, synthetic precursor compounds, intermediates and fine chemicals; it is not popular as an ingredient in food supplements and beverages. However, many of our clients in the United States and the Europe are buying disometin powder from us for their novel supplements already.

    More information of TRB

    Regulation certification
    U.S.FDA,CEP,KOSHER HALAL GMP ISO Certificates
    Reliable Quality
    Nearly 20 years,export 40 countries and regions,more than 2000 batches produced by TRB have no any quality problems,unique purification process,impurity and purity control meet USP,EP and CP
    Comprehensive Quality System

     

    ▲Quality Assurance System

    ▲ Document control

    ▲ Validation System

    ▲ Training System

    ▲ Internal Audit Protocol

    ▲ Suppler Audit System

    ▲ Equipment Facilities System

    ▲ Material Control System

    ▲ Production Control System

    ▲ Packaging Labeling System

    ▲ Laboratory Control System

    ▲ Verification Validation System

    ▲ Regulatory Affairs System

    Control Whole Sources and Processes
    Strictly controlled all raw material,accessories and packaging materials.Preferred raw materials and accessories and packaging materials supplier with U.S. DMF number.Several raw material suppliers as supply assurance.
    Strong Cooperative Institutions to support
    Institute of botany/Institution of microbiology/Academy of Science and Technology/University

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