10-Deacetylbaccatin III (10-DAB)

10-Deacetylbaccatin III (10-DAB) Featured Image
  • 10-Deacetylbaccatin III (10-DAB)

Lus piav qhia luv luv:

10-Deacetylbaccatin III (C29H36O10) yog ib qho bioactive diterpenoid ib txwm muab rho tawm los ntawm cov koob thiab cov tawv ntoo.Taxusntoo (yew ntoo). Raws li ib tug tseem ceeb precursor nyob rau hauv lub semi-synthesis ntawm paclitaxel, docetaxel, thiab lwm yam taxane-based chemotherapeutic agents, 10-DAB yog dav siv nyob rau hauv kws tshuaj R & D thiab oncology tshuaj ntau lawm.

10-Deacetylbaccatin III, tseem hu ua 10-DAB lossis 10-DAB III, yog ib qho kev sib raug zoo ntawm cov organic tebchaw cais tawm ntawm cov koob qhuav thiab cov ceg me ntawm cov ntoo European (Taxus baccata). pacitaxel (taxol); kabazitaxel. 10-10-deacetylbaccatin III tau pom tias xaiv inhibit qhov kev loj hlob ntawm L. DONOVANI intracellular amastigotes hauv J774 murine macrophages hauv vitro ntawm nanomolar concentrations nrog IC (50) tus nqi ntawm 70 nM.


  • FOB Nqe:US 5 - 2000 / KG
  • Min. Order Quantity:1 KG
  • Muaj peev xwm muab khoom:10000 KG / Ib Hlis
  • Chaw nres nkoj:Shanghai / Beijing
  • Cov nqe lus them nqi:L / C, D / A, D / P, T / T, O / A
  • Cov ntsiab lus shipping:Los ntawm hiav txwv / Los ntawm Cua / Los ntawm Courier
  • E-mail:: info@trbextract.com
    • Download tau li PDF

    Product Detail

    Khoom cim npe

    Lub npe tshuaj: 10-Deacetylbaccatin III

    CAS Nr .:

    32981-86-5
    Synonyms:

    10-Desacetylbaccatin III; 10β-Deacetylbaccatin III; (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-(Acetyloxy)-12-(benzoyloxy)-1,2a,3,4,4a,6,9,10,11,12,12a,12b-dod ecahydro-4,6,9,11-tetrahydroxy-4a,8,13,13-tetramethyl-7,11-methano-5H-cyclodeca[3,4]benz[1,2-b]oxet-5-ib; 7,11-Methano-5H-cyclodeca[3,4]benz[1,2-b]oxet-5-ib, 12b-(acetyloxy)-12-(benzoyloxy)-1,2a,3,4,4a,6,9,10,11,12,12a,12b-dodecahydro-4,6,9,11-tetrahydroxy-4a,8,13,13-tetramethyl-, (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS); (Docetaxel USP impurity);10-Deacetylbaccatin III; 10-Deacetyl baccatin; (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS) -1,2a,3,4,4a,6,9,10,11,12,12a, 12b-Dodecahydro-4,6,9,11,12,12b-hexahydroxy-4a,8,13,13-tetramethyl-7,11-methano-5H-cyclodeca[3,4]benz[1,2-b]oxet-5-one 12b-acetate, 12-benzate (USP);
    Molecular form: C29H36O10
    Qhov tsos: Dawb Khoom
    Mol. Qhov hnyav: 544.6 ib
    Cia: 2-8 ° C Lub tub yees

    Subtitle: Plant-Derived API Intermediate, CAS32981-86-5| GMP Certified, COA muab

    10-Deacetylbaccatin III yog dab tsi (10-DAB)?

    10-Deacetylbaccatin III (C29H36O10) yog ib qho bioactive diterpenoid ib txwm muab rho tawm los ntawm cov koob thiab cov tawv ntoo.Taxusntoo (yew ntoo). Raws li ib tug tseem ceeb precursor nyob rau hauv lub semi-synthesis ntawm paclitaxel, docetaxel, thiab lwm yam taxane-based chemotherapeutic agents, 10-DAB yog dav siv nyob rau hauv kws tshuaj R & D thiab oncology tshuaj ntau lawm.

    Ntsiab Specifications & Features

    • Purity: ≥98% (HPLC-UV validated, COA muaj)
    • Cov tsos mob: Dawb mus rau dawb crystalline hmoov
    • Solubility: Soluble hauv methanol, ethanol, DMSO; me ntsis soluble hauv dej
    • Cia: ruaj khov ntawm -20 ° C nyob rau hauv airtight ntim, tiv thaiv los ntawm lub teeb
    • Nroj tsuag Source: Sustainably harvestedTaxus wallichiana(Himalayan yees)

    Applications of 10-DAB

    1. Anticancer Tshuaj Synthesis
      • Qhov nruab nrab tseem ceeb rau kev tsim khoom ib nrab ntawm paclitaxel (Taxol®) thiab docetaxel (Taxotere®).
      • Siv nyob rau hauv R & D rau cov tshiab taxane derivatives tsom rau cov tshuaj tiv thaiv kab mob qog noj ntshav.
    2. Kev tshawb fawb biochemical
      • Kawm txog tubulin polymerization mechanisms thiab apoptosis induction.
      • Cov qauv siv rau kev tshuaj ntsuam chemistry thiab kev tswj kom zoo.
    3. Natural Product Extraction
      • High-yield extraction txheej txheem raws li ntsuab chemistry qauv.

    Vim li cas Source 10-DAB los ntawm peb?

    ✅ Certified Quality:

    • Batch-specific Certificate of Analysis (COA) nrog HPLC, MS, NMR cov ntaub ntawv.
    • Ua raws li USP, EP, thiab ICH Q7 GMP cov lus qhia.

    ✅ Sustainable Sourcing:

    • Ethically sau los ntawm cultivated Taxus plantations (CITES Appendix II raws).

    ✅ Ntiaj teb no Logistics:

    • Seamless txias-chain shipping rau teb chaws USA, EU, thiab APAC cheeb tsam.
    • Customizable ntim (1g rau 1kg, amber iav vials nrog desiccant).

    Kev them nyiaj yug & Cov ntaub ntawv

    • Dawb MSDS (Cov Ntaub Ntawv Kev Nyab Xeeb Cov Ntaub Ntawv) thiab cov ntaub ntawv ruaj ntseg thaum thov.
    • Kev cai synthesis thiab bulk pricing muaj rau OEM cov neeg koom tes.
    • Kev txhawb nqa kev tswj hwm tshwj xeeb rau IND / NDA xa ntawv.

    Kev Nyab Xeeb & Kev Ua Raws Cai

    • CAS Nr .: 32981-86-5
    • Hazard Codes: Kov nrog PPE ( hnab looj tes, tsom iav) - tsis muaj kev phom sij rau kev tshaj lij.
    • Regulatory Status: REACH sau npe; DMF muaj rau cov neeg siv tshuaj.

    FAQs for 10-DAB

    Q: 10-DAB puas tuaj yeem siv ncaj qha hauv kev tshawb fawb kab lis kev cai ntawm tes?
    A: Tsis yog. Nws yuav tsum tau hloov kho tshuaj (xws li, sab-chain ntxiv) los ua bioactive taxanes.

    Q: Lub sijhawm ua haujlwm rau 500g xaj yog dab tsi?
    A: Lub sij hawm tsim khoom txheem: 2-3 lub lis piam. Express shipping muaj.

    Q: Koj puas muab taxane synthesis raws tu qauv?
    A: Yog! Technical whitepapers muaj rau cov neeg tau txais kev pab.

    Nqe lus piav qhia:
    Tau qhov twg los 98% HPLC-qib 10-Deacetylbaccatin III (CAS 32981-86-5) - GMP-certified Taxus extract rau paclitaxel synthesis. Kev txiav txim ntau, COA / MSDS, thiab kev tswj hwm kev txhawb nqa suav nrog.

    1. Ntsiab lus:
      • Primary: “10-Deacetylbaccatin III tsum”, “High purity 10-DAB”, “Paclitaxel precursor”
      • Long-tail: “CAS 32981-86-5 price”, “Taxus extract for cancer research”, “GMP 10-DAB”
    2. Ntsiab lus:
      • "Taxane intermediate", "semi-synthetic paclitaxel", "C29H36O10", "yew ntoo compound"
  • Yav dhau los:
  • Tom ntej:

    • QHOV CHAW UA HAUJ LWM