Aha: Oke anwụrụ ọkụ na-ewepụta 98%Fisetinnke HPLC | Natural Antioxidant & mgbochi ịka nká Mmeju
Okwu:Fisetin98%, HPLC kwadoro, wepụ osisi anwụrụ ọkụ, Antioxidant eke, Mgbakwunye mgbochi ịka nká
1. Nchịkọta ngwaahịa
Mkpụrụ osisi anwụrụ ọkụ 98% Fisetin bụ ihe okike dị oke ọcha nke sitere na yaCotinus coggygria( Osisi anwụrụ ọkụ), ahaziri ka ọ bụrụ 98% Fisetin site na teknụzụ Liquid Chromatography (HPLC) dị elu. Fisetin (C₁₅H₁₀O₆) bụ flavonoid a ma ama maka ike antioxidant, mgbochi mkpali, na senolytic Njirimara, na-eme ka ọ bụrụ ihe a na-achọsi ike na nutraceuticals, ịchọ mma, na usoro ọgwụ.
2. Nkọwapụta isi
- Ihe na-arụ ọrụ: Fisetin ≥98% (HPLC)
- Nọmba CAS:528-48-3
- Ụdị mkpụrụ ndụ: C₁₅H₀O₆
- Ọdịdị: ntụ ntụ edo edo na-egbuke egbuke
- Solubility: Soluble na ethanol, DMSO; ubé soluble na mmiri
- Isi mmalite ihe ọkụkụ:Cotinus coggygriaepupụta na ị ga
- Asambodo: GMP, ISO 9001, COA (Asambodo Analysis) nyere
3. Usoro mmepụta & njikwa mma
3.1 Na-adịgide adịgide mmịpụta
Anyị na-eji mmịpụta CO₂ dị oke egwu iji hụ na enwere ikewapụ Fisetin na-enweghị ihe mgbaze, na-echekwa iguzosi ike n'ezi ihe bioactive ya.
3.2 HPLC ọcha & nkwenye
- Ọnọdụ Chromatographic:
- Ogidi: ZORBAX C18 (4.6×150 mm, 5 μm)
- Usoro mkpanaaka: gradient elution na 5% acetic acid (solvent A) na acetonitrile (solvent B)
- Nchọpụta: nnabata UV na 360 nm, oge njigide ≈11.6-12.6 min (dakọtara na ọkọlọtọ Fisetin)
- Mass Spectrometry (MS):
- Ụdị ion dị mma: m/z 287.05487 (C₁₅H₁₁O₆⁺)
- Ụdị Ion na-adịghị mma: m/z 285.03997 (C₁₅H₉O₆⁻)
- Ụdị nkewa: Ejikọtara ya na ezigbo ụkpụrụ Fisetin iji kwado nhazi molekụla.
3.3 Nkwenye nkwụsi ike
Fisetin na-enwe mmetụta maka ọkụ na okpomọkụ. A na-akwakọba ngwaahịa anyị na iko amber echedoro UV yana ndị na-eme ihe iji hụ na nkwụsi ike n'oge nchekwa na njem.
4. Ngwa & Uru
4.1 Mgbochi ịka nká & Senescence
Fisetin na-arụ ọrụ dị ka onye na-ahụ maka senolytic, na-ahọrọ nke ọma na-ewepụ mkpụrụ ndụ senescent jikọtara na ọrịa ndị metụtara afọ. Nnyocha na-egosi na ọ na-akwalite ogologo ndụ n'ụdị site na ịgbalite ụzọ SIRT1.
4.2 Nchekwa Neuro
Na-agafe ihe mgbochi ụbụrụ ọbara iji belata nrụgide oxidative, nwere ike ibelata ọganihu Alzheimer na Parkinson.
4.3 Mgbochi Ọrịa & Ọrịa Cancer
Na-agbanwe ụzọ NF-κB na COX-2, na-egbochi cytokines pro-inflammatory. Ihe omuma nke mbu na-egosi ntinye apoptosis n'ime sel cancer.
4.4 Cosmeceuticals
Usoro ihe ndị dị n'elu na-eme ka nhịahụ akpụkpọ ahụ dịkwuo mma ma belata mmebi nke UV kpatara site na nkwụsịtụ free radicals.
5. Nkwenye & Nchekwa
- Data toxicity: LD₅₀>2000 mg/kg (ọnụ, oke), nkewa dị ka anaghị egbu egbu.
- Nrube isi n'usoro: zutere ntuziaka USP, EP na FDA maka mgbakwunye nri.
- Allergen-free: Ndị na-abụghị GMO, gluten-free, na vegan-enyi na enyi.
6. Nkwakọ ngwaahịa & ịtụ
- Nha dị: 25kg / drum (oke), 1 n'arọ (nlere anya)
- MOQ: 1 n'arọ (nlekọta); 25 n'arọ maka nnukwu iwu.
- Mbupu zuru ụwa ọnụ: DHL/FedEx nwere nhọrọ yinye oyi maka mpaghara nwere mmetụta okpomọkụ.
7. Ajụjụ
Ajụjụ: Kedu ka esi enyocha ịdị ọcha?
A: Otu ọ bụla na-enweta ule abụọ site na HPLC na MS, yana COA nyere .
Ajụjụ: Fisetin nwere ike dochie quercetin?
A: Ọ bụ ezie na ha abụọ bụ flavonoids, fisetin na-egosipụta bioavailability dị elu na mmetụta senolytic.
Ajụjụ: Ndụ nchekwa?
A: 24 ọnwa mgbe echekwara na ≤25 ° C na akara, ìhè na-eguzogide arịa.
8. Gịnị mere Họrọ Anyị?
- Ọkachamara R&D: Ijikwa ụzọ biosynthesis (dịka ọmụmaatụ, P450 monooxygenase optimization) maka mkpụrụ dị elu.
- Nhazi: ịdị ọcha na-agbanwe agbanwe (50% ~ 98%) na ọrụ OEM dị.
- Njigide: mmịpụta mmiri ethanol dabara na ụkpụrụ kemịkalụ ndụ ndụ.
9. Ntụaka
- Mgbakọ nke ụzọ Biosynthetic Novel maka mmepụta Fisetin (2024).
- HPLC Analysis nke Flavonoids naSophora japonica(Yang et al., 2017).
- A. integrifoliaMwepụta profaịlụ (akwụkwọ ozi sayensị biomedical, 2020)
