Mosi oa Sefate sa Mosi

Sehlooho: Extract ea Premium Smoke Tree 98%Fisetinka HPLC | Tlhaho ea Antioxidant & Anti-Aging Supplement
Mantsoe a sehlooho:Fisetin98%, HPLC E netefalitsoe, Motsoako oa Sefate sa Mosi, Antioxidant ea Tlhaho, Tlatsetso e Khahlanong le Botsofali

1. Tlhaloso ea Sehlahisoa

Smoke Tree Extract 98% Fisetin ke motsoako oa tlhaho oa bohloeki bo phahameng o nkiloeng hoCotinus coggygria(Sefate sa Mosi), se emetsoe ho 98% Fisetin ka theknoloji e tsoetseng pele ea High-Performance Liquid Chromatography (HPLC). Fisetin (C₁₅H₁₀O₆) ke flavonoid e tsebahalang ka thepa ea eona e matla ea antioxidant, anti-inflammatory le senolytic, e etsang hore e be motsoako o batloang ka morao ho li-nutraceuticals, litlolo le metsoako ea meriana.

2. Litlhaloso Tse Bohlokoa

• Motsoako o sebetsang: Fisetin ≥98% (HPLC)
• Nomoro ea CAS:528-48-3
• Foromo ea Limolek'hule: C₁₅H₁₀O₆
• Ponahalo: Phofo e mosehla e khanyang
• Solubility: Ho qhibiliha ka ethanol, DMSO; e qhibilihang hanyane ka metsing
• Mohloli oa Semela:Cotinus coggygriamakhasi le kutu
• Litifikeiti: GMP, ISO 9001, COA (Setifikeiti sa Tlhahlobo) e fanoe

3. Mokhoa oa Tlhahiso & Taolo ea Boleng

3.1 Moetso o tsitsitseng

Re sebelisa tlhahiso ea CO₂ ea supercritical ho netefatsa ho itšehla thajana ha Fisetin, ho boloka botsitso ba bioactive.

3.2 Tlhoekiso le Netefatso ea HPLC

• Maemo a Chromatographic:
  • Kholomo: ZORBAX C18 (4.6×150 mm, 5 μm)
  • Mobile Phase: Gradient elution with 5% acetic acid (Solvent A) le acetonitrile (Solvent B)
  • Ho lemoha: Monyetla oa UV ho 360 nm, nako ea ho boloka ≈11.6-12.6 min (e lumellanang le Fisetin standard)
• Mass Spectrometry (MS):
  • Positive Ion Mode: m/z 287.05487 (C₁₅H₁₁O₆⁺)
  • Mokhoa o Mobe oa Ion: m/z 285.03997 (C₁₅H₉O₆⁻)
  • Mekhoa ea ho arohana: E tsamaellana le litekanyetso tsa 'nete tsa Fisetin ho netefatsa sebopeho sa limolek'hule.

3.3 Tiisetso ea Botsitso

Fisetin e na le kutloelo-bohloko ho khanya le mocheso. Sehlahisoa sa rona se phuthetsoe ka khalase ea amber e sirelelitsoeng ka UV e nang le li-desiccants ho netefatsa botsitso nakong ea polokelo le lipalangoang.

4. Likopo & Melemo

4.1 Khahlanong le Botsofali & Senescence

Fisetin e sebetsa e le moemeli oa senolytic, ka khetho e felisang lisele tsa senescent tse amanang le mafu a amanang le lilemo. Boithuto bo bonts'a hore e ntlafatsa nako ea bophelo mefuteng ka ho kenya tšebetsong litsela tsa SIRT1.

4.2 Tšireletso ea methapo

E tšela mokoallo oa mali le boko ho fokotsa khatello ea oxidative, e leng monyetla oa ho fokotsa tsoelo-pele ea Alzheimer's le Parkinson.

4.3 Lipatlisiso tse khahlanong le ho ruruha le tsa Kankere

E fetola litsela tsa NF-κB le COX-2, e thibelang li-cytokine tsa pro-inflammatory. Lintlha tsa preclinical li fana ka maikutlo a ho kenella ha apoptosis liseleng tsa mofetše.

4.4 Litlolo

Metsoako ea lihlooho e ntlafatsa ho tsitsa ha letlalo le ho fokotsa tšenyo e bakoang ke UV ka ho fokotsa li-radicals tsa mahala.

5. Tumellano le Polokeho

• Lintlha tsa Chefo: LD₅₀>2000 mg/kg (ka molomo, rat), e khetholloang e se chefo.
• Tumellano ea Taolo: E Kopana le litataiso tsa USP, EP, le FDA bakeng sa litlatsetso tsa lijo.
• Ha e na Allergen: Ha e na GMO, ha e na gluten, ebile ha e na li-vegan.

6. Packaging & Ordering

• Bongata bo fumanehang: 25 kg / moropa (boholo), 1 kg (sample)
• MOQ: 1 kg (disampole); 25 kg bakeng sa litaelo tse ngata.
• Global Shipping: DHL/FedEx e nang le likhetho tsa ketane e batang bakeng sa libaka tse se nang mocheso.

7. Lipotso-potso

P: Bohloeki bo netefatsoa joang?
K: Sehlopha se seng le se seng se etsa liteko tse peli ka HPLC le MS, 'me COA e fanoe.

P: Na fisetin e ka nkela quercetin sebaka?
A: Le ha ka bobeli e le li-flavonoids, fisetin e bonts'a bioavailability e phahameng le litlamorao tsa senolytic.

P: Bophelo ba Shelf?
A: Likhoeli tsa 24 ha li bolokiloe ≤25 ° C ka lijaneng tse tiisitsoeng, tse sa keneleng khanya.

8. Ke Hobane'ng ha U Re Khetha?

• Tsebo ea R&D: Ho sebelisa litsela tsa biosynthesis (mohlala, P450 monooxygenase optimization) bakeng sa chai e ngata.
• Boikemisetso: Bohloeki bo ka fetolehang (50% ~ 98%) le lits'ebeletso tsa OEM lia fumaneha.
• Sustainability: Ho ntšoa ha metsi a ethanol ho lumellana le melao-motheo ea k'hemistri e tala.

9. Litšupiso

1. Kopano ea Novel Biosynthetic Pathway for Fisetin Production (2024) .
2. Tlhahlobo ea HPLC ea Flavonoids kaSophora japonica(Yang et al., 2017).
3. A. integrifoliaTlhahisoleseding e Ncha (Lingoloa tsa Saense ea Bophelo bo Botle, 2020)