J-147 Upfu

J-147 Powder Featured Image
  • J-147 Upfu

Tsanangudzo Pfupi

J147 is J-147 isimba rinoshamisa, rinoshanda nemuromo uye rakafara neuroprotective compound ine simba rekusimudzira chiyeuchidzo mumhuka dzakajairika pamwe nekudzivirira kukanganisa kwendangariro muAlzheimer's disease (AD) transgenic mice. Iyo neurotrophic uye yekuyeuka-inosimudzira mabasa eJ-147 inobatanidzwa nekuwedzera kwehuropi hunobva neurotrophic factor (BDNF) mazinga uye kutaura kweBDNF inopindura mapuroteni, kuwedzera kweLTP, kuchengetedzwa kwe synaptic protein, kuderedzwa kweamyloid plaques.

J-147 inonyanya kusimba nemuromo inoshanda neuroprotectant inotorwa zvakanyanya kubva ku curcumin, iyo inoshanda ingredient mu turmeric. Kusiyana necurcumin, inoyambuka ropa-brain barriers zvakabudirira.

J-147 inonyanya kusimba nemuromo inoshanda neuroprotectant inotorwa zvakanyanya kubva ku curcumin, iyo inoshanda ingredient mu turmeric. Kusiyana necurcumin, inoyambuka ropa-brain barriers zvakabudirira. Pakati pavo, J-147 inoshanda nekusunga kuATP synthase. Kuwedzeredza kweATP kwakabatana nekukwegura. Pamusoro pekuwedzera kwemazinga eeurotransmitters NGF neBDNF, J-147 inogona kudzora izvi. Mukuwedzera, J-147 inhibits monoamine oxidase B uye dopamine transporter. Inosimudzira kukura kwehuropi nekuwedzera mazinga e nerve growth factor (NGF) uye brain-derived neurotrophic factor (BDNF). Chinonyanya kukosha, J-147 inogona kusimudzira kukura kwemasero matsva etsinga, kuwedzera kugona kwehuropi kudzidza uye ndangariro, uye kunatsiridza kugona kwekuziva.


  • FOB Mutengo:US 5 - 2000 / KG
  • Min.Order Quantity:1 KG
  • Supply Ability:10000 KG / pamwedzi
  • Port:Shanghai /Beijing
  • Payment Terms:L/C,D/A,D/P,T/T,O/A
  • Mitemo Yekutumira:Negungwa/Nemhepo/Ne Courier
  • E-mail:: info@trbextract.com
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    Product Detail

    Product Tags

    Product Name:J-147 Upfu

    Rimwe Zita:2,2,2-Trifluoroacetic acid 1-(2,4-DiMethylphenyl) -2-[(3-Methoxyphenyl)Methylene]hydrazide],J-147, J147

    Nhamba yeCAS:1146963-51-0

    Muedzo: 99.0%Maminitsi

    Ruvara: Hupfu chena

    Kurongedza: 25kgs Zvigubhu

    Title:J-147 Upfu: Neuroprotective Agent yeAlzheimer's Research & Anti-Aging Application
    Tsanangudzo yeMeta: Ziva J-147 Powder, iyo curcumin-inotorwa neuroprotective komboni ine yakapupurirwa inoshanda mukusimudzira cognition, kuyambuka ropa-brain barriers, uye kunanga chirwere cheAlzheimer. Inowanikwa mune akawanda maratidziro nekutakura kwepasirese.

    Product Highlights

    1. Neuroprotective Powerhouse
      • Muromo unoshanda mubatanidzwa unodzivisa MAO-B (EC50 = 1.88 μM) uye dopamine transporter (EC50 = 0.649 μM)
      • Inowedzera dendritic spine density uye ndangariro mu6-mwedzi-ekuzvarwa mbeva pa200ppm yekudya yekudyara.
      • Clinically yakaedzwa Phase I kuyedza kweAlzheimer's neAbrexa Pharmaceuticals & anotungamira masangano
    2. Multi-Target Anti-Kuchembera Mechanism
      • Inosungira kuATP synthase kudzora mitochondrial basa
      • Inowedzera NGF/BDNF neurotransmitters ichivharira kukuvara kwehuropi
      • Inogadzirisa kuchembera kwevascular nekudzivirira microvascular kuvuza muuropi hwegonzo
    3. Zvidimbu zvehunyanzvi
      • Nhamba yeCAS: 1146963-51-0 | Molecular Formula: C18H17F3N2O2
      • Kuchena: >99% | Solubility: 10 mM muDMSO
      • Aripo Saizi: 1mg-500mg bulk odha | 10mM/1mL mhinduro

    Nhungamiro:

    1. Keyword Integration
      • Chekutanga: "neuroprotective supplement", "Alzheimer's research compounds", "curcumin derivative powder"
      • Muswe wakareba: "MAO-B inhibitor yekuvandudza ruzivo", "anti-kuchembera mitochondrial rutsigiro"
    2. Unyanzvi SEO Kutevedzera
      • Yakagadziriswa data markup yemakemikari zvivakwa (CAS, EC50, molecular uremu)
      • Muchinjikwa-kubatanidza kune zvine hukama zvigadzirwa mapeji (semuenzaniso, CAD-31 derivatives, TrkB agonists)
    3. Mushandisi-Yepakati Dhizaini
      • Amazon-style navigation: Kuruboshwe-kurutivi kupatsanura + yepamusoro yekutsvaga bar
      • Interactive spec ekuenzanisa matafura ane MCE/TargetMol vanokwikwidza

    Zvinhu Zvinovaka Kuvimba

    • Global Logistics: Same-day dispatch (China stock) + tembiricha-inodzorwa kutumira
    • Tsvagiridzo Inotsigirwa: Yakataurwa neSalk Institute, Blanchette Rockefeller Neurosci Inst
    • Yekuchengetedza Mbiri: Hapana genotoxicity inocherechedzwa kusvika ku90μM muCeeTox assays
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