Oleoylethanolamide(OEA)

Product zita:  Oleoylethanolamide , N-Oleoylethanolamide , OEA
Other zita:  N- (2-Hydroxyethyl) -9-Z-octadecenamide, N-oleoyl ethanolamide, Oleoyl monoethanolamide, 9-Octadecenamide, N- (2-Hydroxyethyl) oleamide
CAS No:  111-58-0
Molecular Formular:  C ₂₀H ₃₉NO ₂
Molecular Weight: 325,5
munhu akaidza: 90%, 95%, 85% Maminitsi
Chitarisiko: ruomba-mavara upfu

Oleoylethanolamide is something new to the nutritional market as a popular dietary supplement ingredient used in weight loss formulas. Many bodybuilding fans are discussing oleoylethanolamide on reddit and other social networking platforms.

Oleoylethanolamide wechisikigo metabolite pamusoro oleic asidhi yakaitwa muna ura diki mukati mumuviri womunhu. Zvinonzi sezvingatarisirwa occuring, uye nyanzvi vanouti "endogenous".

OEA is a natural regulator of appetite, weight and cholesterol. It is a natural metabolite that is made in small amounts in your small intestine. OEA helps regulate hunger, weight, body fat and cholesterol by binding to a receptor known as PPAR-Alpha (Peroxisome proliferator-activated receptor alpha). In essence, OEA increases the metabolism of body fat and tells your brain that you are full and it’s time to stop eating. OEA is also known to increase non-exercise related calorie expenditure.

Oleylethanolamide History

Oleoylethanolamide vake chaivo mabasa dzakafukurwa pakazosvika makore 50 apfuura. 2001 asati, hakuna zvakawanda tsvakurudzo pamusoro OEA. Zvisinei, kuti gore, vaongorori Spanish vakaputsa lipid uye vakadzidza sei zviri akaita, apo ikashandiswa uye zvarinoreva. Vakaedza maratidzirwo OEA pamusoro uropi (makonzo) kuburikidza Kubayiwawo jekiseni zvakananga kupinda uropi ventricles. Havana kuwana sei vachidya uye akasimbisa kuti OEA haaiti muuropi, asi kuti zvinokonzera yoga chiratidzo chokuita nzara uye vachidya maitiro.

Oleylethanolamide VS cannabinoid anandamide

Migumisiro OEA vakatanga kudzidza nokuti anoudzawo zvakafanana nomumwe makemikari, mumwe cannabinoid inozivikanwa anandamide. Cannabinoids vari chokuita chirimwa Cannabis, uye anandamides vaivapo muna chirimwa (nembanje) anogona kuwedzera munhu chido tudyo kuburikidza triggering munhu dzichifura mhinduro. Maererano Wikipedia, Oleoylethanolamide ndiye monounsaturated analogue ari endocannabinoid anandamide. Kunyange zvazvo OEA ane mushonga chimiro kuti yakafanana anandamide, migumisiro yayo vachidya uremu zvakanaka zvakasiyana. Kusiyana anandamide, OEA anoita ega cannabinoid gwara, yokudzora PPAR-α basa havi lipolysis.

Structures of various fatty-acid ethanolamides: oleoylethanolamide (OEA), palmitoylethanolamide (PEA) and anandamide (arachidonoylethanolamide, AEA). (Cima Science Co., Ltd is the only manufacturer of bulk raw materials of OEA, PEA and AEA in China, if you need sample and price quote, please drop us an email in the contact us page.)

OEA anotsinga dzakakwirira sungano kuti peroxisome-proliferator kusashanda Kanotokonya-munhu (PPAR-a), mumwe Kanotokonya yenyukireya inodzora zvinoverengeka zvinobatanidzwa lipid muviri.

Natural manyuko oleoylethanolamide

Oleoylethanolamide wechisikigo metabolite pamusoro oleic acid. Saka, zvokudya containg oleic asidhi vanoshandiswa tsime OEA.

Oleic asidhi ndicho chikuru mafuta ari miriwo mafuta akadai emiorivhi, canola uye sunflower. Oleic asidhi kunogona kuwanikwa nati mafuta, nyama, shiri, chizi, etc.

Mishonga mabhuku yakapfuma oleic asidhi dzinosanganisira: Canola Oil, Olive Oil, yekotapeya Oil, Almond Oil, makotapeya, High Oleic Safflower Oil

Zvimwe zvinhu pamusoro Oleic acid:

Chimwe ndicho mafuta somunhu mukaka

Inoumba 25% mafuta ari mukaka

Monounsaturated

Omega-9 nuna asidhi

Chemical fomura ndiye C18H34O2 (CAS 112-80-1)

Ichimuremera kunze triglycerides

Rinoshandiswa pamatunhu akatemerwa mutengo zvizoro somunhu chaizvo moisturizer

Inowanikwa mukaka mafuta, chizi, mafuta omuorivhi, mafuta grapeseed, nzungu, makotapeya, mazai uye nyama

Zvingava nebasa zhinji utano zvakanakira mafuta omuorivhi!

Unoumba Super gamba zvivako nevamwe mukaka mapuroteni kurwisa masero kenza

Oleoylethanolamide Benefits

Oleoylethanolamide (OEA) zvakanaka kuderedza uremu sezvo kudya regulator uye anovatsigira hwakanaka remafuta akawandisa siyana nedzevakuru.

OEA sezvo asafarire kudya

Nzara kudzvinyirira chinhu chikuru kutonga pfungwa nesimba (chikafu) yaunodya, kuronga kudya rwakakosha kudzora utano muviri uremu. OEA controlyour Nzara sei? Unogona kutarisa mashandiro yezviito pazasi.

OEA uye remafuta akawandisa

mafuta omuorivhi chinhu muviri semutambi, uye anobatsira yakaderera "zvakaipa" LDL remafuta akawandisa uye kuwedzera "zvakanaka" HDL. Sei? 85% yamafuta riri oleic acid, uye huru utano metabolite pamusoro oleic asidhi ndiro OEA (Oleoylethanolamide ndiro zita rizere). Naizvozvo, hapana mubvunzo kuti OEA anobatsira healty remafuta akawandisa.

Vamwe rereearch zvinoratidza kuti oleoylethanolamide kunobatsira kufunganya, uye zvakawanda mudungwe munzira uchapupu inodiwa kutsigira.

Manufacutring okumugamuchira Oleoylethanolamide

The flow char of Oleoylethanolamide is below:

Genral matanho ari: reactiong → Kucheneswa muitiro → Filtration → Re-zvazvichanyungudutswa panyaya iyi → hydrogenation → Filtrate Clear Liquid → crystallization → Filtration → Testing → kurongedza → End Product

Mashandiro chiito kuti oleoylethanolamide

Kuisa Zvinongoreva, oleoylethanolamide so nzara regulator. OEA anokwanisa kudzora zvokudya zvako yaunodya nokuudza uropi kuti muviri izere, uye hapana zvokudya zvakawanda zvinodiwa. Iwe udye zvishoma ose zuva, uye muviri wako anogona irege ndakafuta pakupedzisira.

Anti-kufutisa zviito oleoylethanolamide (OEA) iri sezvinoratidzwa mumufananidzo. OEA ari synthesized uye vanounganidzwa mune proximal ura duku kubva zvokudya-hwokurara oleic acid, akadai emiorivhi anonhuwirira. High-mafuta zvokudya anogona tunodzivisa OEA kugadzirwa ari ura. OEA kunoderedza chikafu yaunodya kuburikidza simba homeostatic oxytocin uye histamine uropi hushande uyewo hedonic dopamine anotenderera. Pane uchapupu hwokuti OEA kunogona attenuate hedonic cannabinoid Kanotokonya 1 (CB1R) achipa chiratidzo, kuti activation iyo Rinobatanidzwa kwakawedzera chikafu yaunodya. OEA kunoderedza lipid chokufambisa kupinda adipocytes kutapudzwa mafuta guru. Humwe elucidation migumisiro OEA zvokudya yaunodya uye lipid muviri kuchaita vachiita kutsunga vasiri zvigadziriswe anogona zvakanangwa kutanga tibudirire kufutisa kurapa.

OEA inoshandira Activate chinhu inonzi PPAR uye panguva imwe chete ramps kumusoro mafuta-unopfuta uye kunoderedza mafuta chekuchengeta. Kana muchidya, OEA nhanho kuwedzera uye wako kudya zvinoderedza kana kutsinga dzinouya tsinga kuti kupeji uropi hwako kukuudza kuti uri zvizere. PPAR-α ari boka Kanotokonya ligand kusashanda yenyukireya kuti munyaya majini kutaura lipid muviri uye energyhomeostasis anotenderera.

OEA anoratidza vose zvaraireva zvinoitwa mukaguta chinhu:

(1) It kuchititadzisa kupa kubudikidza nguva refu kuti chinguva unotevera kudya;

(2) kwetunhu arimo nokudzorwa inotonhorera kuwanikwa uye

(3) Its nhanho vanosangana Ritmos nokufamba.

Oleoylethanolamide nemishonga

Oleoylethanolamide kuchengeteka chinhu hanya guru pakati chinamatidzwa pezvitsiga vanoda kuedza ichi itsva pazvokudya dzavo uremu Masvomhu.

Pashure nzwisisika uongororwe iripo mabhuku ose uye data, US Food uye Drug Administration (FDA) akanga asina zvaimunetsa maererano OEA pangozi. RiduZone ndiye wokutanga vakapiswa oleoylethanolamide upfu wemafuta kubva 2015.

Oleoylethanolamide ari metabolite pamusoro oleic acid, inova chikamu utano zuva kudya. Zvinokuchengetedzai kuedza OEA zvokuwedzera, uye hapana zvakakomba nemigumisiro kunge vakaudza.

Migumisiro kunge vakaudza.

Miedzo Oleoylethanolamide dzevanhu

Mune imwe ongororo, makumi mashanu (n = 50) vanhu vanotongwa kuziva kurasikirwa uremu vaiudzwa kuti kutora OEA 2-3 nguva / zuva, maminitsi 15-30 pamberi kudya kwemavhiki 4-12. Nyaya kwaisanganisira avo vakanga vasina kushandiswa uremu zvigadzirwa pamberi, avo vakambotya yaivhuvhuta zviitiko nevamwe uremu zvigadzirwa, avo vane uremu plateaued vamwe uremu nevasori akadai phentermine, avo kuedza kushandisa upenyu Style kuchinja (mugove kuzvidzora uye kurovedza muviri nguva dzose ), uye avo kushingaira vari akakwanisa kwezvokurapa ezvinhu kusanganisira vasingadzoreki shuga kushivirira, dyslipidemia, BP uye zvemwoyo.

Pakuongorora yechipiri, 4 nyaya yekutanga Zviidzo 229, 242, 375 uye 193 LBS azvaitwa, vakarayirwa kuti kutora Oleoylethanolamide capsules (imwe Kamudzira ine 200mg 90% OEA). Nyaya vakatora 4 capsules (1 Kamudzira maminitsi 15-30 vasati zvokudya uye vaifanira kutora imwe Kamudzira vasati zvavo kupfuura zvokudya zuva) zuva nezuva kwemazuva 28. Wokupedzisira nyaya ndambodzidza ndavhiyiwa pamakumbo bhendi placement. Nyaya vakarayirwa kuti havashanduki dzavo kudya uye muviri tsika.

Results

Munguva yokudzidza yokutanga, vanotongwa akarasikirwa avhareji LBS 1-2 / vhiki. Pakanga pasina divi migumisiro kunze chete murwere kusangana zvinopfuura svoto kuti kwakagadziriswa munguva isingasviki vhiki. Kudzidza wechipiri, 3 kubva 4 nyaya yakashuma uremu (3, 7, 15 uye 0 LBS azvaitwa). All 4 vanotongwa yakashuma 10-15% kuderera mugove kukura, kwenguva yakareba Inter-kudya zvikamu, uye hapana marwadzo.

Kana uchifarira mamwe mabhuku nemiedzo kwevanhu OEA, tapota enda Downloadable PDF Links.

Oleoylethanolamide chipimo chemushonga

Pane shoma tsvakurudzo ruzivo pamusoro mamiriro OEA supplementation muvanhu, uye sechinoitika ngozi apo, hapana inokurudzirwa chipimo chemushonga. Zvisinei, pane zvimwe zvokuwedzera ari pamisika, uye unogona kuwana mamwe kwenyu kuzviwana.

The dosing chete zuva RiduZone (vakapiswa OEA / Oleoylethanolamide 90%) ndiyo 200mg (1capsule pamwe chete OEA mariri). Kana sezvaiita pamwe nemamwe uremu zvinhu, nezuva dosing hunoita zvishoma, vanoti 100mg kana 150mg. Somesupplements

Zvinokurudzirwa kuti kutora oleoylethanolamide zvokuwedzera maminitsi 30 vasati zvemangwanani uye kudya, uchawedzera zvizere panguva zvokudya uye somugumisiro zvimwe kudya zvishoma.

Research mabhuku oleoylethanolamide

Oleoylethanolamide: mumwe mutambi itsva simba muviri achidzora. Basa zvokudya yaunodya

Oleoylethanolamide kunowedzera kutaura PPAR-Α uye kunoderedza havi uye muviri uremu mu vakafutisa vanhu: A zvekuchipatara muedzo

Brain Molecules uye Nzara: The Nyaya Oleoylethanolamide

Oleylethanolamide inodzora kudyisa uye muviri uremu kuburikidza activation pamusoro renyukireya Kanotokonya PPAR-munhu

Activation kuti TRPV1 pedyo mukaguta Factor Oleoylethanolamide

Regulation zvokudya yaunodya kubudikidza oleoylethanolamide

Mashandiro kuti oleoylethanolamide pamusoro nuna iine acid uptake mu ura duku pashure zvokudya yaunodya uye muviri uremu rutapudzo

Oleoylethanolamide: Basa iri bioactive lipid amidein modulating kudya maitiro

Oleoylethanolamide: A mafuta shamwari mukurwisa kufutisa

Oleoylethanolamide: A itsva Anotarisirwa Pharmacological Alternative kuna Cannabinoid mhandu nokuda Control kuti Nzara