Oleoylethanolamide(OEA)

Lebitso sehlahisoa:  Oleoylethanolamide , N-Oleoylethanolamide , OEA
Other name:  N- (2-Hydroxyethyl) -9-Z-octadecenamide, N-oleoyl ethanolamide, Oleoyl monoethanolamide, 9-Octadecenamide, N- (2-Hydroxyethyl) oleamide
CAS No:  111-58-0
limolek'hule Formular:  C ₂₀H ₃₉NO ₂
limolek'hule Weight: 325,5
thlahlobo: 90%, 95%, 85% mets
Ponahalo: tranelate 'mala phofo

Oleoylethanolamide is something new to the nutritional market as a popular dietary supplement ingredient used in weight loss formulas. Many bodybuilding fans are discussing oleoylethanolamide on reddit and other social networking platforms.

Oleoylethanolamide ke metabolite ea tlhaho ea acid e oleic entsoeng ka intestine tse nyenyane ka har'a 'mele oa motho. E ka tlhaho occuring, 'me litsebi li e bitsa "e se nang sesosa".

OEA is a natural regulator of appetite, weight and cholesterol. It is a natural metabolite that is made in small amounts in your small intestine. OEA helps regulate hunger, weight, body fat and cholesterol by binding to a receptor known as PPAR-Alpha (Peroxisome proliferator-activated receptor alpha). In essence, OEA increases the metabolism of body fat and tells your brain that you are full and it’s time to stop eating. OEA is also known to increase non-exercise related calorie expenditure.

Oleylethanolamide History

Oleoylethanolamide ya mesebetsi tsa likokoana-hloko li ne li sibolla ka bo-lilemo tse 50 fetileng. Pele selemo sa 2001, ho ne ho se ho etsa lipatlisiso haholo ka OEA. Leha ho le joalo, selemong sona seo, bafuputsi ba Spain e ile ea robeha ka lipid le ithutile kamoo hore lintho li entsoe, moo e lintho li sebediswa le seo e se etsang. Ba lekoa phello ea OEA ka boko (tsa likhoto) ke injecting ka ho toba ka ventricles boko. Ba ile ba fumana se ama ho ja le ho tiisa hore OEA ha a etse lintho ka bokong, empa ho ena le hoo, ho etsa hore motho a pontšo arohaneng e amang tlala le ho ja boitšoaro.

Oleylethanolamide VS cannabinoid anandamide

Liphello tsa OEA ne pele a ithuta hobane arolelanang ho tšoana le lik'hemik'hale e 'ngoe, e cannabinoid tsejoa e le anandamide. Cannabinoids tse amanang le ho dimela Cannabis, le anandamides joale ka dimela (le matekoane) ka eketsa takatso ea hore motho a ho seneke ke qalisa fepa karabo. Ho ea ka Wikipedia, Oleoylethanolamide ke manaka monounsaturated tsa anandamide endocannabinoid. Leha OEA na le sebopeho lik'hemik'hale e tšoanang le anandamide, liphello tsa eona tse ka ho ja le ho taolo ya boima tse fapaneng. Ho fapana le anandamide, OEA sebetsang sebakeng sa hae le nosi tsa cannabinoid tseleng, ho laola mosebetsi PPAR-α ho susumelletsa lipolysis.

Structures of various fatty-acid ethanolamides: oleoylethanolamide (OEA), palmitoylethanolamide (PEA) and anandamide (arachidonoylethanolamide, AEA). (Cima Science Co., Ltd is the only manufacturer of bulk raw materials of OEA, PEA and AEA in China, if you need sample and price quote, please drop us an email in the contact us page.)

OEA tlama le amana phahameng ho peroxisome-proliferator-butswe receptor-e leng (PPAR-a), e receptor tsa nyutlelie hore o laola likarolo tse 'maloa tsa metabolism lipid.

mehloli ea tlhaho ea oleoylethanolamide

Oleoylethanolamide ke metabolite ea tlhaho ea acid e oleic. Ka lebaka leo, lijo tse containg acid e oleic ke mohloli o tobileng oa OEA.

asiti Oleic ke mafura mathomo ka oli ea limela tse kang sefate sa mohloaare, canola le sonobolomo. asiti Oleic ka boela ka fumanoa oli nut, nama, likhoho, chisi, joalo-joalo

mehloli lijo ruileng acid e oleic kenyeletsa: Canola Oil, Olive Oil, avocado oli, Almond Oil, kha li-avocado, High Oleic Safflower Oil

Lintlha tse itseng mabapi le Oleic acid e:

E mong oa mafura atileng ka ho fetisisa ka lebese batho

Etsang 25% ea mafura ka lebese khomo

Monounsaturated

asiti Omega-9 mafura

Lik'hemik'hale moralo ke C18H34O2 (CAS 112-80-1)

Leketlile tsoa le triglycerides

E sebelisoa ka litlolo phahameng turu ka moisturizer e atlehang haholo

Fumanoa ka mafura a lebese, chisi, oli ea mohloaare, oli grapeseed, linate, kha li-avocado, mahe le nama

Ka 'na ba le boikarabelo ba ho fetisisa melemo bophelo bo botle ba oli ea mohloaare e!

Bopa bartolomeo mohale mehahong le liprotheine tse ling tse lebese hore le loane lisele tse bakeng sa kankere

Oleoylethanolamide Melemo

Oleoylethanolamide (OEA) molemo oa ho lahleheloa ke boima ba 'mele ka takatso ea botona kapa regulator le tšehetsa bophelo bo botle k'holeseterole ka batho ba baholo.

OEA ka takatso ea botona kapa suppressant

Takatso ea botona kapa hatelloang ke kgolo laoleng ntlha ya eneji, le (ea lijo) noa, ho laola takatso ea lijo ke ea bohlokoa ho laola 'mele oa ka bophelo bo botle' mele. Joang OEA controlyour takatso ea lijo? O ka sheba mochine liketso tsa mona ka tlase.

OEA le k'holeseterole

oli ea mohloaare e ke superstar phepo e nepahetseng, 'me o thusa ka tlaase "mpe" LDL k'holeseterole le ho eketsa "molemo" HDL. Hobaneng? Ho fihlela ho 85% ya oli ea mohloaare e acid e oleic, 'me tse khōlō ka bophelo bo botle metabolite ea acid e oleic ke OEA (Oleoylethanolamide ke lebitso feletseng). Ka hona, ha ho pelaelo hore OEA thusa healty k'holeseterole.

Ba bang ba rereearch bontša hore oleoylethanolamide na liphello tse ntle ka ho tšoenyeha le litsela tse ngata le bopaki ho hlokahala ho tšehetsa.

Manufacutring tshebetso ya ho Oleoylethanolamide

The flow char of Oleoylethanolamide is below:

mehato Genral ke: reactiong → tlhoekiso thulaganyou e → karaoke set → Re-qhalwa ho ya ka ethanol → hydrogenation → Filtrate Hlakileng Metsi → crystallization → karaoke set → Testing → paka → End Product

Mochine ea nkang khato ea oleoylethanolamide

Ho e beha a bonolo feela, oleoylethanolamide sebetsa e le tlala regulator. OEA ke khona ho laola ho noa lijo tsa hao ka ho bolella boko hore 'mele ke feletseng,' me ha ho na lijo ho hlokahala ho eketsehileng. O ja tlaase ho moo letsatsi le letsatsi, 'me' mele oa hao e ka ha nona haholo ha nako e ntse.

Liketso-ba khahlanong le botenya ba oleoylethanolamide (OEA) e joalokaha ho bontšitsoe setšoantšong. OEA e tsa maiketsetso 'me bokelloa ka proximal intestine nyane ho tswa acid e oleic lijo-nkiloeng, tse kang oli ea mohloaare. Phahameng-mafura a lijo a ka thibela metsoako OEA tlhahiso ea ka intestine le. OEA fokotsa ho noa lijo ka activating homeostatic oxytocin le histamine boko circuitry hammoho le hedonic dopamine litseleng. Ho na le ke bopaki ba hore OEA ka boela attenuate hedonic cannabinoid receptor 1 (CB1R) a bontsa ho, ho Tshebediso ya ea eona e amanang le eketseha ja lijo. OEA fokotsa lipid tsamaisa ka adipocytes ho fokotseha boima mafura. Ho ekelletsa moo elucidation tsa liphello tsa OEA ka ja lijo le ho lipid metabolism tla thusa ka boikemisetso ba mekgwa fisioloji hore ka targeted ho ntshetsa pele atlehang haholoanyane botenya phekolo.

OEA sebetsa ho ebe o kenya tshebetsong ntho e bitswang PPAR le ka nako ramps fihlela mafura-bo tukang le decreases polokelo mafura. Ha u ja, OEA maemo eketsa le takatso ea lijo decreases ha methapo kutlo hore li amahanya ho boko ba hao ho bolela hore u se u e tletseng. PPAR-α ke sehlopha sa ligand-butswe receptor tsa nyutlelie o neng o akarelletsa ho polelo e reng phatsa ea lefutso ea lipid metabolism le energyhomeostasis litseleng.

OEA bontša kaofela ha litšobotsi tse hlalosang a satiety Ntlha e:

(1) Ho thibela ho fepa ka ho prolonging le karohano ho lijo le hlahlamang;

(2) tswakana Eona e laolwa ke ho fumaneha phepo le

(3) maemo a eona feta liphetoho circadian.

litla Oleoylethanolamide lehlakoreng

polokeho Oleoylethanolamide ke kameho ea seholo har'a Brands tlatsetsa ba batla ho leka ena motsoako o bukeng ka boima ba 'mele mekhoa bona.

Ka mor'a tlhahlobo akaretsang tsa lingoliloeng tsohle le ho fumaneha ya data, le US Lijo le Lithethefatsi Administration (FDA) ne ke se na dingongoreho mabapi le polokeho OEA e. RiduZone ke pele le diselefounu tsa oleoylethanolamide phofo motsoako ho tloha ka 2015.

Oleoylethanolamide ke metabolite ea acid e oleic, e leng karolo ea bophelo bo botle ja lijo letsatsi le letsatsi. Ke bolokehile ho leka OEA a tlatsana le, 'me ha e le tse tebileng liphello tse bohloko li' nile tsa tlaleha.

litla di tlalehile.

re thulana le liteko Oleoylethanolamide batho

Phuputsong e 'ngoe, mashome a mahlano (n g = 50) bafo batho ba thahasellang ho lahleheloa ke boima ba' mele li ne li eletsa ho nka OEA makhetlo 2-3 / ka letsatsi a, metsotso 15-30 pele lijo ka libeke tse 4-12. Bafo ba kenyeleditsweng ba neng ba sa tloaela ho lahleheloa ke boima ba 'mele lihlahisoa pele, batho ba nang le phihlelo liketsahalo tse bohloko le lihlahisoa tse ling tsa boima ba' mele, bao boima ba tahlehelo plateaued ka mahlahana a tse ling tse boima ba 'mele tse kang phentermine, ba leka ho kenya bophelo setaele liphetoho (taolo kabelo le ho ikoetlisa kamehla ), 'me ba ka mafolofolo ho ntse ho tsamaiswa ho maemo a tsa bongaka ho akarelletsa le tsoekere mamello litsebeng, dyslipidemia, kgatelelo ya madi le mafu a pelo le methapo.

Ka ho ithuta bobeli, 4 bafo le litekanyo ya motheo ea 229, 242, 375 le 193 liponto ka latellana, ba ile ba laeloa hore ba nke Oleoylethanolamide capsules (komiki e mong e nang le 200mg 90% OEA). Bafo ba nka 4 capsules (1 komiki metsotso 15-30 pele lijo 'me ba ne ba lokela ho nka e komiki e eketsehileng pele ho lijo tsa bona kholo ka ho fetisisa ea letsatsi) letsatsi le letsatsi bakeng sa matsatsi a 28. Ka taba ena ea ho qetela pele ba neng ba undergone liropeng sehlopha placement. Bafo ba ile ba laeloa ho etsa se liphetoho ho ja lijo le ho ikoetlisa ho bona mekhoa e metle.

Results

Ka ho ithuta pele, bafo lahlehileng e leng karolelano ea liponto 1-2 / beke. Ho ne ho litla na lehlakoreng ka ntle bakeng sa ho ba le mamello e mong nang e fetang ho nyekoa ke pelo le hore o ne a ka etsa qeto ea ho ka tlase ho beke. Ka ho ithuta bobeli, 3 ho ba bafo ba 4 tlalehile ho lahleheloa ke boima ba 'mele (3, 7, 15 le 0 liponto ho latellana). bafo bohle 4 e ile ea tlaleha 10-15% fokotseha ka boholo le kabelo, tšoaneng ka nako e telele hara-lijo, le litla na lehlakoreng.

Haeba o na le thahasello ka lingoliloeng tse eketsehileng liteko batho le OEA, ka kopo etela tjarollo maqhama PDF.

Oleoylethanolamide litekanyetso li behoa

Ho na le e fokolang ho etsa lipatlisiso tlhahisoleseding e mabapi le morao-rao OEA tlatseletsong ho batho, 'me ha nkoa e le sireletsehileng, ho na le ho na litekanyetso li behoa kgothaletswa. Leha ho le joalo, ho na le ba bang ba a tlatsana le tse rekisoang, 'me o ka fumana ba bang ba bakeng sa ya referense hao.

The dosing ka letsatsi la RiduZone (le diselefounu tsa OEA / Oleoylethanolamide 90%) ke 200mg (1capsule le feela OEA ho eona). Ha mokgwa oo kopantsweng hammoho le leng metsoako boima ba 'mele, ho dosing letsatsi bonahala e le ka tlaase ho moo, re 100mg kapa 150mg. Somesupplements

E kgothaletswa ho nka oleoylethanolamide a tlatsana le metsotso e 30 pele ho lijo tsa hoseng le tsa mantsiboea, o tla ikutloa a feletseng ho feta nakong ea lijo ka lebaka leo e tla ka etsahala hore ebe ho ja tlaase ho moo.

Ho etsa lipatlisiso ka har'a lingoliloeng tsa ka oleoylethanolamide

Oleoylethanolamide: le lecha sebapali ka taolo ya eneji, metabolism. Karolo e Phethoang ke ka ja lijo

Oleoylethanolamide eketsa pontšo ea PPAR-Α le ho fokotsa takatso ea lijo 'me boima ba' mele ka ho batho ba batenya ho tlola tekano: A teko ea tleleniki

Boko limolek'hule le takatso ea lijo: The Case tsa Oleoylethanolamide

Oleylethanolamide o laola ho fepa 'mele boima ka Tshebediso ya tsa libetsa tsa nyutlelie receptor PPAR-e leng

Tshebediso ya ya TRPV1 ke Satiety Ntlha Oleoylethanolamide

Molao oa tsamaiso ya ho noa lijo ke oleoylethanolamide

Mochine oa oleoylethanolamide ka mafura acid e uptake ka intestine nyane ka mor'a ho noa lijo 'me' mele phokotso boima

Oleoylethanolamide: The karolo e phethoang ke lipid bioactive amidein modulating ja boitšoaro bo

Oleoylethanolamide: A motsoalle mafura ho loantša botenya

Oleoylethanolamide: A bukeng Bokhoni diokobatsi seng ho fapana Cannabinoid ba khahlanong le lōna bakeng sa Control takatso ea lijo