Magaca badeecada:5-aminolevulinic acid Phosphate
La mid ah:5-ALA
CAS Maya:868074-65-1
Daahirsanaanta: ≧98.0%
Midabka: huruud fudud ilaa budo cad
Xaalada GMO:GMO Bilaash
Xirmooyinka: 25kgs durbaannada fiber-ka
Kaydinta: Weelka ha furin meel qabow oo qalalan, ka fogow iftiinka xooggan
Life Life:24 bilood laga bilaabo taariikhda wax soo saarka
5-Aminolevulinic Acid FosfateALA) Sharaxaada Alaabta
Dulmarka alaabta
5-Aminolevulinic Acid Fosfate (5-ALA phosphate)waa soosaarayaal amino acid si dabiici ah u soo baxa, oo si weyn loogu aqoonsaday doorkeeda muhiimka ah ee hababka noolaha sida heme iyo chlorophyll biosynthesis. Iyada oo leh lambarka CAS ee 868074-65-1, waxay u muuqataa sida budo crystalline caddaan iyo caddaan ah waxaana lagu heli karaa qaabka-cunnada (95% daahirnimo) iyo heerka dawooyinka (98% daahirnimo). Qaaciddeeda kelli waa C5H12NO7P (miisaanka kelli: 229.125), waxayna muujinaysaa milmayn sare oo biyaha ah (50 mg/mL).
Codsiyada Muhiimka ah
- Daawooyinka & Isticmaalka Daaweynta
- Daawaynta Sawirka Daawaynta (PDT):ALAwaa dawo-yaqaan loo beddelay protoporphyrin IX (PPIX), sawir-qaade loo isticmaalo in lagu beegsado laguna burburiyo unugyada kansarka hoostooda mawjadaha iftiinka gaarka ah. Waa FDA-loo oggolaaday soo-saarka glioma iyo daaweynta kansarka maqaarka.
- Maareynta Atherosclerosis: Daraasaduhu waxay muujinayaan daawaynta sonodynamic ee dhexdhexaadka ah ee ALA waxay yaraynaysaa samaynta huurada iyadoo kor u qaadaysa waxqabadka makrophage.
- Sawirka Cilad-sheegidda: ALA-sababtay fluorescence waxay caawisaa meelaynta saxda ah ee buro inta lagu jiro qaliinka.
- Codsiyada Beeraha
- Xakamaynta koritaanka dhirta, ALA waxay wanaajisaa photosynthesis, neefsiga, iyo dulqaadka walbahaarka, hagaajinta wax-soosaarka dalagga iyo tayada.
- Warshadaha qurxinta
- Noocyada ALA-ku jira waxay hagaajiyaan fuuq-baxa maqaarka waxayna yareeyaan laalaabyada, iyadoo tijaabooyin caafimaad ay muujinayaan waxtarka qiyaasaha hooseeya (tusaale, 31 ng/maalintii) .
Badbaadada & Farmashiyaha
- Xogta Badbaadada: Qiyaasta hoose ee fosfooraska ALA si wanaagsan ayaa loo dulqaatay. Biyo-soo-saarka afka ayaa gaadha 100%, iyadoo 34% laga soo saaray kaadida oo aan isbeddelin 12 saacadood gudahood. Daraasadaha hore ee daaweynta ayaa xaqiijinaya inaysan jirin wax sun ah oo muhiim ah marka la eego qiyaasaha lagu taliyey .
- Digniin: ALA xad-dhaaf ah ayaa laga yaabaa inay keento walaaca oksaydhka xaalado naadir ah (tusaale, porphyria), laakiin isticmaalka la xakameeyey wuxuu yareeyaa khataraha.
Wax soo saarka & Tayada
- Advanced Synthesis: InjineerE. koliNoocyada (tusaale, PIECE) waxay wanaajiyaan wax soo saarka ALA iyada oo loo marayo dib u habeynta qulqulka dheef-shiid kiimikaadka, gaarista wax-soo-saarka ilaa 8.21 g/L.
- Heerarka Adag: Alaabtayadu waxay u hoggaansantaa tilmaamaha GMP, iyadoo la hubinayo joogtaynta codsiyada dawooyinka iyo cuntada.
Baakadaha & Kaydinta
- Baakadaha: Waxaa lagu heli karaa 25kg/Drum (warshad) ama 1 kg/bac (isticmaalka cilmi baarista) .
- Kaydinta: Ku kaydi weelasha daboolan, iftiinka-ilaa ee 2-8 ° C si loo ilaaliyo xasilloonida ilaa 2 sano.
Waa maxay sababta aan u dooranay fosfatkayaga ALA?
- Multifunctional: Codsiyada kala duwan ee daawada, beeraha, iyo qurxinta.
- Nadiif Sare: QC adag waxay hubisaa ≥95% (cuntada) iyo ≥98% (farmasiga) nadiifnimada.
- Cilmi-badhis-Baadhid: Waxaa taageeraya tijaabooyinka bukaan-socodka iyo daraasadaha dheef-shiid kiimikaadka.
Erayada furaha: 5-ALA phosphate, heme biosynthesis, photodynamic therapy, nidaamiyaha koritaanka dhirta, CAS 868074-65-1
