Dzina la mankhwala: 5-aminolevulinic asidi Phosphate
Mawu ofanana:5-ALA
Nambala ya CAS:868074-65-1
Kuyera: ≧98.0%
Mtundu:Ufa wachikasu mpaka woyera
Mkhalidwe wa GMO: GMO Yaulere
Kulongedza: mu 25kgs fiber ng'oma
Kusungirako: Sungani chidebe chosatsegulidwa pamalo ozizira, owuma, Khalani kutali ndi kuwala kwamphamvu
Shelf Life: Miyezi 24 kuyambira tsiku lopangidwa
5-Aminolevulinic Acid Phosphate (ALA) Mafotokozedwe Akatundu
Zowonetsa Zamalonda
5-Aminolevulinic Acid Phosphate (5-ALA phosphate)ndi chochokera mwachilengedwe chochokera ku amino acid, chodziwika bwino chifukwa cha gawo lake lofunika kwambiri pazachilengedwe monga heme ndi chlorophyll biosynthesis. Ndi nambala ya CAS 868074-65-1, ikuwoneka ngati ufa wonyezimira wonyezimira wonyezimira ndipo umapezeka m'magulu a chakudya (95% chiyero) ndi mankhwala amtundu wa mankhwala (98% chiyero) . Mapangidwe ake a molekyulu ndi C5H12NO7P (kulemera kwa maselo: 229.125), ndipo amawonetsa kusungunuka kwakukulu m'madzi (50 mg/mL) .
Mapulogalamu Ofunika Kwambiri
- Kugwiritsa Ntchito Zachipatala & Zochizira
- Photodynamic Therapy (PDT):ALAndi mankhwala ochiritsira omwe amasinthidwa kukhala protoporphyrin IX (PpIX), photosensitizer yomwe imagwiritsidwa ntchito kuloza ndikuwononga ma cell a khansa pansi pa mafunde apadera a kuwala. Ndilovomerezedwa ndi FDA pakuchotsa glioma komanso chithandizo cha khansa yapakhungu.
- Atherosulinosis Management: Kafukufuku akuwonetsa kuti ALA-mediated sonodynamic therapy imachepetsa mapangidwe a plaque popititsa patsogolo ntchito za macrophage.
- Kujambula Kwachidziwitso: ALA-induced fluorescence imathandizira kukhazikika kwa chotupa panthawi ya opaleshoni.
- Ntchito Zaulimi
- Monga chowongolera kukula kwa mbewu, ALA imakulitsa photosynthesis, kupuma, komanso kulekerera kupsinjika, kukulitsa zokolola ndi zabwino.
- Makampani Odzikongoletsera
- Mapangidwe okhala ndi ALA amathandizira kuti khungu liziyenda bwino komanso limachepetsa makwinya, ndikuyesa kwachipatala kuwonetsa kuchita bwino pamilingo yocheperako (mwachitsanzo, 31 ng/tsiku).
Chitetezo & Pharmacokinetics
- Mbiri Yachitetezo: Mlingo wochepa wa ALA phosphate umaloledwa bwino. Mkamwa bioavailability kufika 100%, ndi 34% excreted osasinthika mkodzo mkati 12 hours. Maphunziro a preclinical amatsimikizira kuti palibe chiwopsezo chachikulu pamilingo yovomerezeka.
- Chenjezo: Kuchulukitsitsa kwa ALA kungayambitse kupsinjika kwa okosijeni nthawi zina (monga porphyria), koma kugwiritsa ntchito moyenera kumachepetsa ngozi.
Kupanga & Quality
- Advanced Synthesis: EngineeredE. kolizovuta (mwachitsanzo, PIECE) zimakulitsa kupanga kwa ALA kudzera pakusinthanso kagayidwe kachakudya, kupeza zokolola mpaka 8.21 g/L.
- Miyezo Yokhwima: Zogulitsa zathu zimagwirizana ndi malangizo a GMP, kuwonetsetsa kusasinthika kwamankhwala ndi zakudya.
Kupaka & Kusunga
- Kupaka: Imapezeka mu 25 kg/drum (ya mafakitale) kapena 1 kg/thumba (ntchito ya kafukufuku) .
- Kusungirako: Sungani muzitsulo zotsekedwa, zotetezedwa ndi kuwala pa 2-8 ° C kuti zikhale zokhazikika kwa zaka ziwiri.
Chifukwa Chiyani Sankhani ALA Phosphate Yathu?
- Multifunctional: Ntchito zosiyanasiyana muzamankhwala, ulimi, ndi zodzoladzola.
- Kuyera Kwambiri: QC yolimba imatsimikizira ≥95% (chakudya) ndi ≥98% (pharma) chiyero.
- Kafukufuku Wothandizidwa: Mothandizidwa ndi mayesero azachipatala ndi maphunziro a metabolic.
Mawu osakira: 5-ALA phosphate, heme biosynthesis, chithandizo cha photodynamic, chowongolera kukula kwa mbewu, CAS 868074-65-1
