Paclitaxel is a monomer diterpenoid compound extracted from Natural Plant Paclitaxel bark, is a kind of complex secondary metabolites, is currently understood only a drug can promote microtubule polymerization and stability of microtubules have been aggregated. Isotope tracing showed that paclitaxel was bound only to polymerized microtubules, not to the polymerized tubulin two. Cell contact paclitaxel after the accumulation of a large number of microtubules in cells, which interfere with microtubule accumulation of various cellular functions, especially the cell division stop in mitosis, blocking the normal cell division
Igama Product: Paclitaxel 99 .0%
Form: White crystalline powder
Ukucaciswa: 99%
Uvavanyo Indlela: solibalo
CAS Number: 33069-62-4
Ifomula Ezinto: C47H51NO14
Iqondo Point :957,115 ° C kwi 760 mmHg
Ezinto Ubunzima: 853,91
yeMfuzo Ubume: yeMfuzo Free
Ukupakisha: ngo 25kgs imigqomo ifayibha
Storage: Gcina isikhongozeli bengawatyi apha, kwindawo eyomileyo epholileyo, Gcina kude wokukhanya onamandla
Ubude bethuba Life: iinyanga ezingama-24 ukususela kumhla yemveliso
umsebenzi:
1.Paclitaxel kakhulu lisetyenziswe ovarian kunye nencum umhlaza, umhlaza wemiphunga, umhlaza colorectal, wolusu, intloko kunye nomhlaza emqaleni, lymphoma, yaye kwakhona nempembelelo ethile ngamathumba ebuchotsheni.
2.It na amachiza uzinzo ukuba ukukhuthaza microtubule polymerization kunye microtubule polymerization.
3.There uya eziyintlanganisela inani elikhulu microtubules iiseli emva kokuba sesichengeni paclitaxel, beqokelela microtubules ephazamisa kunye nemisebenzi iseli, ingakumbi, stoped division iseli mitosis, uvimba hlula iseli eqhelekileyo.
isicelo:
Isetyenziswa kuphononongo lwesakhiwo kunye nomsebenzi microtubles zibe tubulin. Paclitaxel ngoku kusetyenziswa izigulane aphathe lung, ovarian, umhlaza webele, intloko kunye nomhlaza entanyeni, kunye neentlobo ezinge- advanc of nee- kaThixo. Paclitaxel i inhibitor mitotic ezisetyenziswa umhlaza ichemotherapy.
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