Paclitaxel 99.0%

Paclitaxel is a monomer diterpenoid compound extracted from Natural Plant Paclitaxel bark, is a kind of complex secondary metabolites, is currently understood only a drug can promote microtubule polymerization and stability of microtubules have been aggregated. Isotope tracing showed that paclitaxel was bound only to polymerized microtubules, not to the polymerized tubulin two. Cell contact paclitaxel after the accumulation of a large number of microtubules in cells, which interfere with microtubule accumulation of various cellular functions, especially the cell division stop in mitosis, blocking the normal cell division

Product Name:Paclitaxel 99.0%

Form:White crystalline powder
Specification: 99%

Test Method : HPLC

CAS Number: 33069-62-4

Molecular Formula:C47H51NO14

Boiling Point：957.115 °C at 760 mmHg
Molecular Weight:  853.91
GMO Status:GMO Free

Packing: in 25kgs fiber drums

Storage:Keep container unopened in cool, dry place,Keep away from strong light

Shelf Life:24 months from date of production

Function:

1.Paclitaxel is mainly applied to ovarian and breast cancer, lung cancer, colorectal cancer,melanoma, head and neck cancer, lymphoma, and it also have a certain effect on brain tumors.

2.It is stability drugs that can promote microtubule polymerization and microtubule polymerization.
3.There will be accumulated a large number of microtubules in the cells after exposure to paclitaxel, the accumulation of microtubules interferes with cell functions, in particular, stoped cell division in mitosis, blocking normal cell division.

Application:

Used in the study of structure and function of microtubles into tubulin. Paclitaxel is now used to treat patients with lung, ovarian, breast cancer, head and neck cancer, and advanc ed forms of Kaposi’s sarcoma. Paclitaxel is a mitotic inhibitor used in cancer chemotherapy.