Paclitaxel 99.0%

Short Description:

Paclitaxel is a monomer diterpenoid compound extracted from Natural Plant Paclitaxel bark, is a kind of complex secondary metabolites, is currently understood only a drug can promote microtubule polymerization and stability of microtubules have been aggregated. Isotope tracing showed that paclitaxel was bound only to polymerized microtubules, not to the polymerized tubulin two. Cell contact paclitaxel after the accumulation of a large number of microtubules in cells, which interfere with microtubule accumulation of various cellular functions, especially the cell division stop in mitosis, blocking the normal cell division


  • FOB Price: US $0.5 - 9,999 / KG
  • Min.Order Quantity: 1 KG
  • Supply Ability: 10000 KG/per Month
  • Port: SHANGHAI/BEIJING
  • Payment Terms: L/C,D/A,D/P,T/T
  • Product Detail

    Product Tags

    Paclitaxel is a monomer diterpenoid compound extracted from Natural Plant Paclitaxel bark, is a kind of complex secondary metabolites, is currently understood only a drug can promote microtubule polymerization and stability of microtubules have been aggregated. Isotope tracing showed that paclitaxel was bound only to polymerized microtubules, not to the polymerized tubulin two. Cell contact paclitaxel after the accumulation of a large number of microtubules in cells, which interfere with microtubule accumulation of various cellular functions, especially the cell division stop in mitosis, blocking the normal cell division

    Product Name:Paclitaxel 99.0%

    Form:White crystalline powder
    Specification: 99%

    Test Method : HPLC

    CAS Number: 33069-62-4

    Molecular Formula:C47H51NO14

    Boiling Point957.115 °C at 760 mmHg
    Molecular Weight:  853.91
    GMO Status:GMO Free

    Packing: in 25kgs fiber drums

    Storage:Keep container unopened in cool, dry place,Keep away from strong light

    Shelf Life:24 months from date of production

    Function:

    1.Paclitaxel is mainly applied to ovarian and breast cancer, lung cancer, colorectal cancer,melanoma, head and neck cancer, lymphoma, and it also have a certain effect on brain tumors.

    2.It is stability drugs that can promote microtubule polymerization and microtubule polymerization.
    3.There will be accumulated a large number of microtubules in the cells after exposure to paclitaxel, the accumulation of microtubules interferes with cell functions, in particular, stoped cell division in mitosis, blocking normal cell division.

    Application:

    Used in the study of structure and function of microtubles into tubulin. Paclitaxel is now used to treat patients with lung, ovarian, breast cancer, head and neck cancer, and advanc ed forms of Kaposi’s sarcoma. Paclitaxel is a mitotic inhibitor used in cancer chemotherapy.

    More information of TRB

    Regulation certification
    U.S.FDA,CEP,KOSHER HALAL GMP ISO Certificates
    Reliable Quality
    Nearly 20 years,export 40 countries and regions,more than 2000 batches produced by TRB have no any quality problems,unique purification process,impurity and purity control meet USP,EP and CP
    Comprehensive Quality System

     

    ▲Quality Assurance System

    ▲ Document control

    ▲ Validation System

    ▲ Training System

    ▲ Internal Audit Protocol

    ▲ Suppler Audit System

    ▲ Equipment Facilities System

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    ▲ Production Control System

    ▲ Packaging Labeling System

    ▲ Laboratory Control System

    ▲ Verification Validation System

    ▲ Regulatory Affairs System

    Control Whole Sources and Processes
    Strictly controlled all raw material,accessories and packaging materials.Preferred raw materials and accessories and packaging materials supplier with U.S. DMF number.

    Several raw material suppliers as supply assurance.

    Strong Cooperative Institutions to support
    Institute of botany/Institution of microbiology/Academy of Science and Technology/University

     


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