Paclitaxel is a monomer diterpenoid compound extracted from Natural Plant Paclitaxel bark, is a kind of complex secondary metabolites, is currently understood only a drug can promote microtubule polymerization and stability of microtubules have been aggregated. Isotope tracing showed that paclitaxel was bound only to polymerized microtubules, not to the polymerized tubulin two. Cell contact paclitaxel after the accumulation of a large number of microtubules in cells, which interfere with microtubule accumulation of various cellular functions, especially the cell division stop in mitosis, blocking the normal cell division
Ingoa Hua: Paclitaxel 99 .0%
Puka: White paura, tioata
Whakapūtātanga: 99%
Test Tikanga: HPLC
CAS Tau: 33069-62-4
Tātai rāpoi: C47H51NO14
Pokarekare Point :957,115 ° C i 760 mmHg
rāpoi Taumaha: 853,91
Tūnga koiora kua: koiora kua Free
Tarapēke: i roto i te 25kgs pahu muka
Storage: Kia mau ipu āu i raumati, wahi maroke, Puritia atu i te marama kaha
Shelf Life: 24 marama i te rā o te hanga
taumahi:
Kei te nuinga 1.Paclitaxel tono ki ovarian me te uma pukupuku, mate pukupuku pūkahukahu, mate pukupuku colorectal, tonapuku, upoko me te mate pukupuku kaki, lymphoma, a reira ano hoki i tetahi pānga i runga i te pukupuku roro.
Ko 2.It drugs pūmautanga e taea whakatairanga microtubule polymerization me microtubule polymerization.
Ka 3.There kia putu he maha nui o microtubules i roto i te pūtau i muri i te rongo ki paclitaxel, te haaputuputuraa o microtubules poka ki mahi pūtau, i roto i ngā, stoped wehenga pūtau i roto i te whāū pūira, ārai wehewehenga pūtau noa.
Taupānga:
Whakamahia i roto i te ako o te hanganga me te mahi o microtubles ki tubulin. Kei te Paclitaxel inaianei whakamahia ki tūroro whāki ki pūkahukahu, ovarian, mate pukupuku uma, upoko me te mate pukupuku kaki, me ngā puka ed advanc o sarcoma o Kaposi. Paclitaxel Ko te inhibitor mitotic whakamahia i roto i te hahau mate pukupuku.
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