PRL-8-53, ndi nootropic zatsopano, yemwenso amadziwika ndi mankhwala dzina methyl 3- [2- [benzyl (methyl) kwa amino] ethyl] benzoate ndi kupanga nootropic enaake. Iwo anayamba kupanga mu 1970 ndi Dr. Nikolaus Hansl pa University Creighton ku Nebraska. Wakhala uli ndi ena maphunziro anthu amene anasonyeza mayankho abwino ntchito chidziwitso. Kafukufuku wina anasonyeza kuti pawiri zingathandize kupeza otaika kukumbukira (hypermnesia).
Mankhwala Dzina: PRL-8-53
Other Dzina: methyl 3- (2- (benzylmethylamino) ethyl) benzoate hydrochloride
3- (2-benzylmethylaminoethyl) benzoic asidi asidi methyl Ester hydrochloride
3- (2- (methyl (phenylmethyl) kwa amino) ethyl) benzoic asidi asidi methyl Ester hydrochloride
Number CAS: 51352-87-5
Zofufuza: 98%
Maonekedwe: White ufa
Kodi PRL-8-53 Ntchito?
PRL-8-53 lachokera ku mitundu asidi benzoic asidi ndi phenylmethylamine. Kapangidwe mankhwala anapanga ku mitundu awiriwa zotsatira mankhwala mu pawiri kuti akhoza kupereka ndi maselo cholinergic, amene mukugwira nawo modulating kukumbukira ndi kuphunzira njira mkati ubongo. PRL-8-53 imatchedwanso kuti potentiate (kuonjezera zotsatira za) dopamine pang'ono ziletsa serotonin zolandilira. Dr. Nikolaus Hansl ankakhulupirira kuti mbiri zotsatira mwina kuyambitsa anasintha wa bwino mu CNS machitidwe mtundu ndi kuyambitsa uziyenda bwino aluntha.
Pali kokha la munthu matenda kuphunzira preformed kupenda zotsatira za mankhwala ndipo anasonyeza kuti zinthu zikuyenda bwino mu kukumbukira mawu, zithunzi anachita nthawi ndi kulamulira galimoto, makamaka iwo amene pa zaka 30. Anthu achikulire amakonda kwambiri nkhani pamtima ndipo kuchepa chidziwitso Choncho, kukumbukira ndi zowonjezera chidziwitso utithandize amakonda ntchito bwino pa iwo.
RPL-8-53 Nchito:
Owongolera nzeru maganizo
Aziyankha kukumbukira ndi mphamvu atatsamira
Kusintha mphamvu ubongo angathetsere mavuto komanso kuteteza ku mankhwala kapena kuvulala thupi
Owongolera mlingo zolinga
Owongolera ulamuliro wa yokhudza kotekisi / subcortical limagwirira ubongo
Kusintha maganizo imalandira
Mlingo ndi mankhwalawo
Mfundo setifiketi kupezeka kwa PRL 8-53 zikusonyeza osiyanasiyana 0.01-4mg / kg wa bodyweight. Komabe, ngati kuti ndi osiyanasiyana lalikulu kwambiri, osiyanasiyana abwino ndi 0.05-1.2 mg / kg. Izi anamasuliridwa kuti 3.4mg-81.6mg kwa 150 mapaundi munthu ndi 4.55mg-109mg kwa 200 mapaundi munthu. Mu yesero anthu, zotsatira palibe mbali analembedwa; Komabe, yafupika galimoto ntchito tinaonera mbewa ndi makoswe akaperekedwa Mlingo waukulu wa PRL 8-53
