I-melatonin is an indoleamine neurohormone found across plants and animals, produced endogenously from serotonin (5-HT) and secreted in animals as a regulatory signal for synchronization of the circadian rhythm and the sleep-wake cycle. The melatonin receptor system, consisting of the MEL-1A-R, MEL-1B-R, and MT3 subtypes, demonstrates particular plasticity and modularity – antagonists such as Luzindole (sc-202700) and 2-Phenylmelatonin (sc-203466) show modification of systemic responses to the Melatonin signal without impeding activation of the receptors by Melatonin. Powerful antioxidant activity is associated with Melatonin, and it is known to provide protection to lipids, proteins, and DNA against oxidative damage. Several antioxidant enzymes are shown to be upregulated by Melatonin, including glutathione peroxidase, superoxide dismutases, and catalase. Melatonin also scavenges free radicals as a terminal antioxidant, reacting to generate stable end products and terminate radical chain reactions. Free movement through the blood-brain barrier positions Melatonin as a particularly significant endogenous antioxidant. Melatonin is a rat NOS1 (nNOS) inhibitor. Melatonin is an activator of MEL-1A-R and MEL-1B-R.
Igama lomkhiqizo: melatonin
CAS Ayikho: 73-31-4
Isithako: I-melatonin 99% ngo HPLC
Umbala: off-elimhlophe ukukhanya powder ephuzi isici iphunga nokunambitheka
Isimo GMO: GMO Mahhala
Ukupakisha: e 25kgs fibre izigubhu
Isigcini: Gcina esitsheni lizihlalele e cool, endaweni eyomile, Dedani ekukhanyeni okunamandla
Shelf Life: izinyanga 24 kusukela ngosuku ukukhiqizwa
umsebenzi:
-Helps alawule nezinye hormone kanye nokugcina isigqi lomzimba somzimba
-Melatonin powder futhi kusiza ukulawula isikhathi
-Melatonin powder kusiza ukucacisa
-Melatonin powder kunemiphumela eqinile antioxidant
-Release hormone zesifazane zokuzala
Isicelo:
Powder -Melatonin is ngokwemvelo akhiqizwa imigwamanda bezibona ukukhanya
-Melatonin powder isetshenzisiwe adambise ukuqwasha, ukulwa jet Lag, ukuvikela amaseli khulula-olukhulu umonakalo, lithuthukisa isimiso somzimba sokuzivikela, umdlavuza, futhi wandise ukuphila.