Isitolo esidayisa yonke impahla melatonin abakhiqizi nabaphakeli | Tong Rui Bio-Tech

I-melatonin

I-melatonin Image Efakiwe
  • I-melatonin

Incazelo emfushane:

I-melatonin kuyinto neurohormone indoleamine Tholakala kulo lonke zezitshalo nezilwane, ekhiqizwa endogenously kusukela serotonin (5-HT) kanye ethakwa izilwane kuwuphawu zokulawula ukuvumelanisa we isigqi lomzimba kanye umjikelezo wokulala-wake. Uhlelo melatonin yokwamukela, eyayihlanganisa MEL-1A-R, MEL-1B-R, futhi MT3 subtypes, ubonisa plasticity ethile futhi modularity - abamelene ezifana Luzindole (sc-202700) no-2-Phenylmelatonin (sc-203466) ukukhombisa ukuguqulwa yezimpendulo letindzala isignali melatonin ngaphandle ebezingathuntubeza ukusebenza la mangqamuzana ngu-melatonin. umsebenzi antioxidant Inamandla lihlotshaniswa melatonin, futhi ukunikeza isivikelo ukuze lipids, amaphrotheni, DNA ekulimaleni oxidative ezaziwayo. enzyme eziningana antioxidant izinto zibonakala upregulated ngu-melatonin, kuhlanganise glutathione peroxidase, dismutases superoxide, futhi catalase. I-melatonin futhi scavenges radicals khulula njengoba antioxidant esibulalayo, ukusabela ukukhiqiza imikhiqizo sekupheleni ozinzile futhi anqamule olukhulu uchungechunge ukusabela. ukunyakaza Mahhala ngokusebenzisa kusivimbeli gazi ebuchosheni nekubeka melatonin njengoba antioxidant eziphawuleka ngokukhethekile endogenous. I-melatonin kuyinto rat NOS1 (nNOS) inhibitor. I-melatonin kuyinto Activator ka MEL-1A-R MEL-1B-R.


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    umkhiqizo Imininingwane

    umkhiqizo Amathegi

    I-melatonin is an indoleamine neurohormone found across plants and animals, produced endogenously from serotonin (5-HT) and secreted in animals as a regulatory signal for synchronization of the circadian rhythm and the sleep-wake cycle. The melatonin receptor system, consisting of the MEL-1A-R, MEL-1B-R, and MT3 subtypes, demonstrates particular plasticity and modularity – antagonists such as Luzindole (sc-202700) and 2-Phenylmelatonin (sc-203466) show modification of systemic responses to the Melatonin signal without impeding activation of the receptors by Melatonin. Powerful antioxidant activity is associated with Melatonin, and it is known to provide protection to lipids, proteins, and DNA against oxidative damage. Several antioxidant enzymes are shown to be upregulated by Melatonin, including glutathione peroxidase, superoxide dismutases, and catalase. Melatonin also scavenges free radicals as a terminal antioxidant, reacting to generate stable end products and terminate radical chain reactions. Free movement through the blood-brain barrier positions Melatonin as a particularly significant endogenous antioxidant. Melatonin is a rat NOS1 (nNOS) inhibitor. Melatonin is an activator of MEL-1A-R and MEL-1B-R.

     

    Igama lomkhiqizo: melatonin

    CAS Ayikho: 73-31-4

    Isithako:  I-melatonin 99% ngo HPLC

    Umbala: off-elimhlophe ukukhanya powder ephuzi isici iphunga nokunambitheka

    Isimo GMO: GMO Mahhala

    Ukupakisha: e 25kgs fibre izigubhu

    Isigcini: Gcina esitsheni lizihlalele e cool, endaweni eyomile, Dedani ekukhanyeni okunamandla

    Shelf Life: izinyanga 24 kusukela ngosuku ukukhiqizwa

     

    umsebenzi:

    -Helps alawule nezinye hormone kanye nokugcina isigqi lomzimba somzimba
    -Melatonin powder futhi kusiza ukulawula isikhathi
    -Melatonin powder kusiza ukucacisa
    -Melatonin powder kunemiphumela eqinile antioxidant 
    -Release hormone zesifazane zokuzala 

     

    Isicelo:

    Powder -Melatonin is ngokwemvelo akhiqizwa imigwamanda bezibona ukukhanya
    -Melatonin powder isetshenzisiwe adambise ukuqwasha, ukulwa jet Lag, ukuvikela amaseli khulula-olukhulu umonakalo, lithuthukisa isimiso somzimba sokuzivikela, umdlavuza, futhi wandise ukuphila.

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