melatonin is an indoleamine neurohormone found across plants and animals, produced endogenously from serotonin (5-HT) and secreted in animals as a regulatory signal for synchronization of the circadian rhythm and the sleep-wake cycle. The melatonin receptor system, consisting of the MEL-1A-R, MEL-1B-R, and MT3 subtypes, demonstrates particular plasticity and modularity – antagonists such as Luzindole (sc-202700) and 2-Phenylmelatonin (sc-203466) show modification of systemic responses to the melatonin signal without impeding activation of the receptors by Melatonin. Powerful antioxidant activity is associated with Melatonin, and it is known to provide protection to lipids, proteins, and DNA against oxidative damage. Several antioxidant enzymes are shown to be upregulated by Melatonin, including glutathione peroxidase, superoxide dismutases, and catalase. Melatonin also scavenges free radicals as a terminal antioxidant, reacting to generate stable end products and terminate radical chain reactions. Free movement through the blood-brain barrier positions Melatonin as a particularly significant endogenous antioxidant. Melatonin is a rat NOS1 (nNOS) inhibitor. Melatonin is an activator of MEL-1A-R and MEL-1B-R.
Product aha: melatonin
CAS No: 73-31-4
Mgwa: melatonin 99% site HPLC
Agba: anya-na-acha ọcha na ìhè edo edo powder na e ji mara isi na uto
GMO Status: GMO Free
Mbukota: na 25kgs eriri rụọ
Nchekwa: Nọgidenụ na akpa unopened na jụụ, akọrọ ebe, na-pụọ ike ìhè
Adịghị adị Life: 24 ọnwa si ụbọchị nke mmepụta
Function:
-Helps mezie ọzọ homonụ na ịnọgide na-enwe ahụ circadian n'afọ iri na ụma
-Melatonin powder-enyekwara ịchịkwa oge
-Melatonin powder enyere chọpụta
-Melatonin ntụ ntụ nwere ike antioxidant mmetụta
-Release nke nwanyi omumu homonụ
ngwa:
-Melatonin powder-adịkarị na-emepụta na ahụ omume uzọ nke ìhè
-Melatonin powder e ji mee ka mfe ehighị ụra nke ọma, ọgụ ugboelu lag, chebe mkpụrụ ndụ free-buu mmebi, mbo mbuli dịghịzi usoro, gbochie cancer, na ịgbatị ndụ.
