gaosi ma e tuuina oloa siiatoa Melatonin | Tong Rui leʻo-Tech

Melatonin

Melatonin Image o loo Faaalia
  • Melatonin

Faamatalaga puupuu:

Melatonin o se neurohormone indoleamine maua i le salafa o laau ma meaola, e gaosia endogenously mai serotonin (5-HT) ma secreted i manu e pei o se faailoilo o tulafono faatonutonu mo synchronization o le pao circadian ma le faataamilosaga o le moe-tutupu ai. O le faiga receptor melatonin, e aofia ai le Mel-1A-R, Mel-1B-R, ma MT3 subtypes, faaalia faapitoa plasticity ma modularity - tagata tetee e pei o Luzindole (TO-202700) ma le 2-Phenylmelatonin (TO-203466) faaali fesuiaiga o tali faiga i le faailo Melatonin e aunoa ma faalavelave faatoaagaina mai o le receptors e Melatonin. ua fesootai gaoioiga antioxidant mamana faatasi ai ma Melatonin, ma ua lauiloa i le maua ai le puipuiga e lipids, polotini, ma DNA e faasaga i mea ua faaleagaina oxidative. enzymes antioxidant le tele o loo faaalia e upregulated e Melatonin, e aofia ai glutathione peroxidase, superoxide dismutases, ma catalase. scavenges foi Melatonin radicals saoloto o se antioxidant tigaina, le tali e maua ai le oloa fale o manu iuga ma faamuta tali filifili māeʻa. gaoioiga saoloto e ala i le tofiga papupuni toto-faiai Melatonin o se antioxidant endogenous taua faapitoa. Melatonin o se isumu NOS1 (nNOS) inhibitor. Melatonin o se activator o Mel-1A-R ma Mel-1B-R.


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    Faamatalaga oloa

    pine o oloa

    Melatonin is an indoleamine neurohormone found across plants and animals, produced endogenously from serotonin (5-HT) and secreted in animals as a regulatory signal for synchronization of the circadian rhythm and the sleep-wake cycle. The melatonin receptor system, consisting of the MEL-1A-R, MEL-1B-R, and MT3 subtypes, demonstrates particular plasticity and modularity – antagonists such as Luzindole (sc-202700) and 2-Phenylmelatonin (sc-203466) show modification of systemic responses to the Melatonin signal without impeding activation of the receptors by Melatonin. Powerful antioxidant activity is associated with Melatonin, and it is known to provide protection to lipids, proteins, and DNA against oxidative damage. Several antioxidant enzymes are shown to be upregulated by Melatonin, including glutathione peroxidase, superoxide dismutases, and catalase. Melatonin also scavenges free radicals as a terminal antioxidant, reacting to generate stable end products and terminate radical chain reactions. Free movement through the blood-brain barrier positions Melatonin as a particularly significant endogenous antioxidant. Melatonin is a rat NOS1 (nNOS) inhibitor. Melatonin is an activator of MEL-1A-R and MEL-1B-R.

     

    Oloa Igoa: Melatonin

    CAS leai: 73-31-4

    Vaega:  Melatonin  99% le HPLC

    Valivali: ese-papae e pei o le efuefu samasama malamalama ma le uiga manogi ma tofo

    GMO Tulaga: Free GMO

    Teuina: i 25kgs drums fibre

    Teuina: Tausi pusa tatalaina i mālū, nofoaga matutu, Ia o ese mai le malamalama malosi

    Fata Olaga: O le 24 masina mai le aso o le tuuina

     

    galuega tauave:

    -Helps faatonutonu isi homone ma faatumauina le pao circadian o le tino
    -Melatonin fesoasoani foi efuefu pulea le taimi
    -Melatonin efuefu fesoasoani fuafuaina
    efuefu -Melatonin ei ai aafiaga antioxidant malosi 
    -Release o homone fanautama fafine 

     

    talosaga:

    Ua tuuina masani efuefu -Melatonin i le tino i le tali atu i le vaaiga o le malamalama
    ua faaaogaina efuefu -Melatonin e faamama moe fiti, taua lelava, puipuia sela mai saoloto-māeʻa faaleagaina, uunaia ai le faiga sao, taofia le kanesa, ma tuuina atu le ola.

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