Melatonin is an indoleamine neurohormone found across plants and animals, produced endogenously from serotonin (5-HT) and secreted in animals as a regulatory signal for synchronization of the circadian rhythm and the sleep-wake cycle. The melatonin receptor system, consisting of the MEL-1A-R, MEL-1B-R, and MT3 subtypes, demonstrates particular plasticity and modularity – antagonists such as Luzindole (sc-202700) and 2-Phenylmelatonin (sc-203466) show modification of systemic responses to the Melatonin signal without impeding activation of the receptors by Melatonin. Powerful antioxidant activity is associated with Melatonin, and it is known to provide protection to lipids, proteins, and DNA against oxidative damage. Several antioxidant enzymes are shown to be upregulated by Melatonin, including glutathione peroxidase, superoxide dismutases, and catalase. Melatonin also scavenges free radicals as a terminal antioxidant, reacting to generate stable end products and terminate radical chain reactions. Free movement through the blood-brain barrier positions Melatonin as a particularly significant endogenous antioxidant. Melatonin is a rat NOS1 (nNOS) inhibitor. Melatonin is an activator of MEL-1A-R and MEL-1B-R.
Dzina mankhwala: Melatonin
CAS No: 73-31-4
Chofunika: Melatonin 99% ndi HPLC
Mtundu: kuchokera woyera kuwala ufa koma wachikasu ndi fungo khalidwe ndi kukoma
GMO Momwe: GMO Free
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Yosungirako: Khalani chidebe osatsegulidwa ozizira, youma, Khalani kutali ndi kuwala amphamvu
Alumali Moyo: miyezi 24 kuchokera tsiku kupanga
-Helps zonse mahomoni ena ndiponso kukhala ndi thupi circadian mungoli
-Melatonin ufa Amathandizanso kuchepetsa nthawi ya
-Melatonin ufa kumathandiza kudziwa
-Melatonin ufa ali amphamvu antioxidant zotsatira
-Release mahomoni ubereki wamkazi
Ufa -Melatonin mwachibadwa m'thupi poyankha amaonera kuwala
-Melatonin ufa lakhala likugwiritsidwa ntchito kuti tisaletse tulo, nkhondowo kwakusiyana kwanthawi, kuteteza maselo ufulu-kwakukulu kuwonongeka, chitetezo cha m'thupi, kupewa khansa, ndi moyo wautali.