Beta-nicotinamide Mononucleotide (NMN), a ngwaahịa nke NAMPT mmeghachi omume na a isi nad + n'etiti, ameliorates glucose ekweghị ibe nọrọ site Iweghachi nad + etoju ke HFD na-akpata T2D ụmụ oke. NMN nwekwara enhances hepatic insulin uche na-eweghachi site n'usoro okwu metụtara oxidative nchegbu, mkpali nzaghachi, na circadian n'afọ iri na ụma, nwere obere site SIRT1 ebighị. NMN na-eji na-amụ na-adịgide adịgide motifs n'ime RNA aptamers na ribozyme ebighị Filiks metụtara β-nicotinamide mononucleotide (Beta-NMN) -activated RNA iberibe.
Nicotinamide mononucleotide ( "NMN" na "β-NMN") bụ a nucleotide ewepụtara ribose na nicotinamide. Niacinamide (nicotinamide,) bụ ụdị vitamin B3 (niacin.) Dị ka a Biochemical precursor nke nad +, ọ pụrụ ịbụ uru na mgbochi nke pellagra.
Ya unconcentrated ụdị, niacin, a hụrụ na a dịgasị iche iche nke ekwukwa n'akwụkwọ isi mmalite: Ahụekere, Mushrooms (portobello, grilled), Avocados, Green peas (ọhụrụ), na ụfọdụ azụ na anụ meats.
Na ọmụmụ [on ụmụ oke], NMN egosiwo laa azu afọ metụtara ọbara dysfunction iwetulata oxidative nchegbu.
Name: Beta-Nicotinamide Mononucleotide
CAS #: 1094-61-7
Product name: Beta-Nicotinamide Mononucleotide；NMN
Other aha: β-D-NMN; BETA-NMN; beta-D-NMN; NMN zwitterion; Nicotinamide Ribotide; Nicotinamide nucleotide; Nicotimide mononucleotide; Nicotinamide mononuclotide
CAS: 1094-61-7
molekụla usoro: C11H15N2O8P
molekụla arọ: 334,22
Ọcha: 98%
Nchekwa okpomọkụ: 2-8 ° C
Ọdịdị: White ntụ ntụ
Iji: mgbochi ịka nká
Function:
1.Nicotinamide mononucleotide mmadụ mkpụrụ ndụ na-egwu ọrụ dị mkpa ike na emana, ọ idem ke intracellular nad (nicotinamide ebe adenin dinucleotide, cell ume akakabarede mkpa coenzyme) njikọ, na-eji na-emegide ịka nká, ịda ọbara sugar na ndị ọzọ na nlekọta ahụ ike na ngwaahịa.
2. Nicotinamide Mononucleotide bụ a mmiri-soluble vitamin, The ngwaahịa bụ ọcha crystalline ntụ ntụ, odorless ma ọ bụ ihe fọrọ nke nta odorless, ilu na uto, unu kpamkpam soluble na mmiri ma ọ bụ ethanol, dissolvable na glycerin.
3.Nicotinamide Mononucleotide dị mfe banye onu, na ike ga-ekesa ke idem, ngafe metabolites ma ọ bụ prototype ngwa ngwa chụpụ si mmamịrị. Nicotinamide bụ akụkụ nke coenzyme m na coenzyme II, na arụ orụ ọrụ nke hydrogen nnyefe ke ndu ọxịdashọn akụkụ okuku ume na yinye, nwere ike kwalite ndu ọxịdashọn Filiks na anụ ahụ metabolism, ịnọgide na-enwe nkịtị anụ ahụ (karịsịa akpụkpọ, digestive tract na ụjọ usoro) ike n'ezi nwere ọrụ dị mkpa .
Ke adianade do, nicotinamide nwere mgbochi na ọgwụgwọ nke obi ngọngọ, imi ọnụ ọrụ na mgbochi-ngwa-ngwa ibuo arrhythmias, nicotinamide ike budata melite obi ọnụego na atrioventricular ngọngọ mere site verapamil.
