Beta-nicotinamide Mononucleotide (NMN), a ọja ti awọn NAMPT lenu ati ki o kan bọtini nad + agbedemeji, ameliorates glukosi mìíràn pin nipa mimu-pada sipo nad + ipele ninu HFD-induced T2D eku. NMN tun iyi wiwu hisulini ifamọ ati restores pupọ ikosile jẹmọ si ti oyi wahala, iredodo Esi, ati ni lilu ti ilu, gba nipasẹ SIRT1 ibere ise. NMN ti lo fun keko abuda motifs laarin RNA aptamers ati ribozyme ibere ise lakọkọ okiki β-nicotinamide mononucleotide (Beta-NMN) -activated RNA ajẹkù.
Nicotinamide mononucleotide ( "NMN" ati "β-NMN") ni a Nucleotide yo lati ribose ati nicotinamide. Niacinamide (nicotinamide,) ni a fọọmu ti Vitamin B3 (niacin.) Bi awọn kan biokemika ṣaaju ti nad +, o le jẹ wulo ninu awọn idena ti pellagra.
Awọn oniwe-unconcentrated fọọmu, niacin, ti wa ni ri ni orisirisi kan ti onje awọn orisun: peanuts, olu (portobello, ti ibeere), avocados, Green Ewa (alabapade), ati awọn eja ati eranko meats.
Ni ẹrọ [lori eku], NMN ti han lati ẹnjinia ori-jẹmọ inu okan alailoye nipa dinku oyi wahala.
Name: Beta-Nicotinamide Mononucleotide
CAS #: 1094-61-7
Product name: Beta-Nicotinamide Mononucleotide；NMN
Miiran orukọ: β-D-NMN; BETA-NMN; Beta-D-NMN; NMN zwitterion; Nicotinamide Ribotide; Nicotinamide Nucleotide; Nicotimide mononucleotide; Nicotinamide mononuclotide
CAS: 1094-61-7
molikula agbekalẹ: C11H15N2O8P
molikula àdánù: 334,22
Purity: 98%
Ibi otutu: 2-8 ° C
Irisi: White lulú
Lo: egboogi-ti ogbo
iṣẹ:
1.Nicotinamide mononucleotide ni eniyan ẹyin mu ohun pataki ipa ni agbara iran, o lowo ninu inuselula nad (nicotinamide adinini dinucleotide, alagbeka agbara iyipada pataki coenzyme) kolaginni, lo ninu egboogi-ti ogbo, ti kuna ẹjẹ suga ati awọn miiran itoju ilera awọn ọja.
2. Nicotinamide Mononucleotide ni a omi-tiotuka Vitamin, Awọn ọja ni funfun okuta lulú, odorless tabi fere odorless, kikorò ni lenu, larọwọto tiotuka ninu omi tabi ọti ẹmu, dissolvable ni glycerin.
3.Nicotinamide Mononucleotide jẹ rorun lati fa roba, ati ki o le wa ni o gbajumo pin ninu ara, awọn excess metabolites tabi Afọwọkọ ni kiakia lé lati ito. Nicotinamide jẹ ara coenzyme emi ati coenzyme II, yoo ni ipa ti hydrogen ifijiṣẹ ni ibi ifoyina atẹgun pq, o le se igbelaruge ti ibi ifoyina lakọkọ ati àsopọ iṣelọpọ, bojuto deede àsopọ (paapa ni awọ-ara, ti ounjẹ ngba ati aifọkanbalẹ eto) ìwà títọ ni o ni ohun pataki ipa .
Ni afikun, nicotinamide ni o ni idena ati itoju ti ọkàn Àkọsílẹ, alafo eti ati ẹnu ipade iṣẹ ati egboogi-sare esiperimenta arrhythmias, nicotinamide le significantly mu awọn okan oṣuwọn ati atrioventricular Àkọsílẹ ṣẹlẹ nipasẹ verapamil.
