Beta-nicotinamide Mononucleotide (NMN), mankhwala a NAMPT anachita ndi nad kiyi + wapakatikati, ameliorates shuga tsankho ndi kubwezeretsa nad + misinkhu mu mbewa HFD chovutika T2D. NMN komanso timapitiriza kwa chiwindi insulin tilinazo ndi kubweretsa jini akuti zokhudzana ndi nkhawa zobwera chifukwa cha okosijeni, yotupa Poyankha, ndi mungoli circadian, mwina kudzera SIRT1 kutsegula. NMN ntchito pophunzira amajambulapo maluwa okongola kumangako mkati aptamers RNA ndi njira ribozyme kutsegula yokhudza β-nicotinamide mononucleotide (Woyeselela-NMN) -activated RNA zidutswa.
Nicotinamide mononucleotide ( "NMN" ndi "β-NMN") ndi nyukiliotayidi anachokera ku ribose ndi nicotinamide. Niacinamide (nicotinamide,) ndi mtundu wa vitamini B3 (niacin.) Monga kalambulabwalo amuzolengedwa wa nad +, zikhonza kukhala zothandiza kupewa pellagra.
Mawonekedwe ake unconcentrated, niacin, opezeka mu njira zosiyanasiyana zopangira zakudya: Mtedza, Bowa (portobello, kukazinga), mapeyala, Green nandolo (atsopano), ndi zina nsomba ndi nyama nyama.
Mu maphunziro [pa mbewa], NMN watisonyeza chigamulocho obwera ndi ukalamba wolumikizira kukanika ndi kucheperachepera nkhawa zobwera chifukwa cha okosijeni.
Name: Beta-Nicotinamide Mononucleotide
CAS #: 1094-61-7
Product name: Beta-Nicotinamide Mononucleotide；NMN
Other dzina: β-D-NMN; BETA-NMN; beta-D-NMN; NMN zwitterion; Nicotinamide Ribotide; Nicotinamide nyukiliotayidi; Nicotimide mononucleotide; Nicotinamide mononuclotide
CAS: 1094-61-7
maselo chilinganizo: C11H15N2O8P
maselo Kulemera kwake: 334,22
Oyera: 98%
yosungirako Kutentha: 2-8 ° C
Maonekedwe: ufa White
Ntchito: odana ndi ukalamba
ntchito:
1.Nicotinamide mononucleotide maselo anthu mbali yofunika kwambiri mu m'badwo mphamvu, izo nawo okhudza maselo ambiri nad (nicotinamide adenine dinucleotide, mphamvu selo kutembenuka zofunika coenzyme) kaphatikizidwe, ntchito odana ndi ukalamba kugwa shuga ndi zina zaumoyo.
2. Nicotinamide Mononucleotide ndi madzi sungunuka mavitamini, mankhwala ndi woyera crystalline ufa, odorless kapena pafupifupi odorless owawa kukoma, momasuka sungunuka m'madzi kapena Mowa, dissolvable mu glycerin.
3.Nicotinamide Mononucleotide n'zosavuta kuyamwa m'kamwa, ndipo akhoza inafalitsidwa mu thupi, metabolites owonjezera kapena zinachitika mofulumira kutulutsa kuchokera mkodzo. Nicotinamide ndi mbali ya coenzyme Ine ndi coenzyme II, atenge mbali ya yobereka wa hydrogen mu kwachilengedwenso makutidwe ndi okosijeni m'mapapo unyolo, akhoza kulimbikitsa njira kwachilengedwenso makutidwe ndi okosijeni ndipo thupi minofu, kukhala minofu yachibadwa (makamaka khungu thirakiti m'mimba ndi mantha dongosolo) okhulupirika ali ndi udindo wofunika .
Komanso, nicotinamide ali kupewa ndi kuchiza wa chipika mtima, ntchito nkusani mfundo ndi odana ndi kudya experimental arrhythmias, nicotinamide akhoza kwambiri patsogolo mlingo mtima ndi chipika atrioventricular chifukwa cha verapamil.
